5 completed. 3 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
Follow aceclidine: new trials by email Literature Review of aceclidine trials Research Report on aceclidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese With Presbyopia LNZ101 (Aceclidine /Brimonidine) ophthalmic solution, LNZ100 (Aceclidine) ophthalmic solution, Placebo (Vehicle) ophthalmic solution - Presbyopia | Phase 1 | Completed | Corxel Pharmaceuticals | 21 | 2024-03-04 | 2024-04-23 |
| Plasma Pharmacokinetics and Safety of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Subjects With Presbyopia Aceclidine + Brimonidine, Aceclidine - Eye Diseases, Presbyopia | Phase 1 | Completed | LENZ Therapeutics, Inc | 30 | 2023-07-06 | 2023-10-16 |
| Evaluation of the Safety and Effectiveness of Aceclidine (LNZ101) and Aceclidine + Brimonidine (LNZ100) in the Treatment of Presbyopia Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle proprietary ophthalmic solution - Presbyopia, Refractive Errors | Phase 2 | Completed | LENZ Therapeutics, Inc | 59 | 2022-08-06 | 2024-09-05 |
| Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the Treatment of Presbyopia Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle Proprietary Ophthalmic Solution - Presbyopia, Refractive Errors | Phase 2 | Completed | LENZ Therapeutics, Inc | 68 | 2022-05-05 | 2024-09-05 |
| A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia Aceclidine+tropicamide combination, Aceclidine, Vehicle - Presbyopia | Phase 2 | Completed | LENZ Therapeutics, Inc | 58 | 2017-04-30 | 2022-09-22 |
Presbyopia (5) · Eye Diseases (3) · Refractive Errors (3) · Myopia (2)
LENZ Therapeutics, Inc (4) · Corxel Pharmaceuticals (1)
United States (4) · China (1)
Alisyn Facemire, BA (2) · Gail Torkildsen, MD (1) · Kris Gameblin (1) · Larry Li, Doctor (1)