39 completed, 7 unknown, 4 recruiting, 3 withdrawn. 58 Phase 2, 16 Phase 3, 5 Phase 1.
Follow Pregnancy: new trials by email Literature Review of Pregnancy trials Research Report on Pregnancy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Substance Use in Pregnancy - Optimizing Retention in Treatment by Maximizing Opportunities for Management Contingency Management, Social Drivers of Health Screening - Pregnancy, Substance Use Disorder (SUD) | Phase 2 | Not yet recruiting | Washington University School of Medicine | 245 | 2027-01-01 | 2026-08-20 |
| Impact of Standardization on Outcomes Following Cervical Ripening Cervical Ripening with a double balloon catheter only, Cervical ripening with a double balloon catheter plus misoprostol, Usual-care control group - Pregnancy | Phase 2 / Phase 3 | Recruiting | Indiana University | 1158 | 2026-07-29 | 2026-10-27 |
| Phase 2b, Open Label, Multisite, Randomized Crossover Study of DPP Versus 2PR DPP, 2PR, Free Choice - Pregnancy, HIV Infections | Phase 2 | Not yet recruiting | HIV Prevention Trials Network | 300 | 2026-05-15 | 2026-02-19 |
| Efficacy of Cabergoline in Inhibiting Lactation and Alleviating Breast Symptoms Cabergoline, Placebo - Pregnancy, Abortion | Phase 2 | Recruiting | Jefferson Drapkin | 348 | 2026-03-16 | 2026-09-17 |
| Probiotic Supplementation in Optimizing Iron and Hematological Status Among Pregnant Females Lactiplantibacillus plantarum 299v, Placebo Capsule(s) - Iron Deficiency (ID), Pregnancy | Phase 2 | Recruiting | University of Illinois Chicago | 250 | 2026-02-01 | 2026-11-02 |
| CREATE - Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy CAB LA 600mg, RPV LA 900mg, CAB LA 400mg - HIV-1-infection, Pregnancy | Phase 1 / Phase 2 | Withdrawn | National Institute of Allergy and Infectious Diseases (NIAID) | 2025-05-01 | 2025-07-31 | |
| Optimizing PrEP Regimens for Pregnant Women in Sub-Saharan Africa (O-PrEP Study) - Stage 1 FTC/TDF 200mg/300mg, FTC/TDF 300mg/450mg, FTC/TDF 400mg/600mg - HIV, Prevention | Phase 2 | Completed | University of North Carolina, Chapel Hill | 54 | 2024-06-18 | 2026-02-17 |
| Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV Rifapentine, Isoniazid - HIV Seropositivity, Pregnancy | Phase 1 / Phase 2 | Active not recruiting | The Aurum Institute NPC | 252 | 2024-01-17 | 2025-12-12 |
| Endeavor to Stop Nausea/Vomiting Associated With Pregnancy (E-SNAP) Mirtazapine - Pregnancy, Severe Nausea and Vomiting | Phase 1 / Phase 2 | Withdrawn | Northwestern University | 2022-06-13 | 2024-12-11 | |
| Letrozole and Misoprostol for Termination of Pregnancy up to 63 Days' Gestation 30 mg letrozole followed by 800 mcg misoprostol - Pregnancy | Phase 2 | Completed | Gynuity Health Projects | 40 | 2021-12-09 | 2022-06-15 |
| Tenofovir in Pregnancy to Prevent Mother to Child Transmission of Hepatitis B. Tenofovir Disoproxil Fumarate - Hepatitis B, Tenofovir | Phase 2 | Completed | University of Oxford | 27 | 2021-01-08 | 2024-03-27 |
| Pharmacologically-based Strategies for Opioid Substitution Therapy During Pregnancy Magnitude Group, Frequency Group - Opiate Addiction, Pregnancy | Phase 2 | Terminated | Steve N. Caritis, MD | 13 | 2019-04-13 | 2024-08-29 |
| The Effect of Probiotics on Maintenance of Health in Pregnancy and Infants Probiotic, Placebo - Pregnancy | Phase 2 | Completed | Lallemand Health Solutions | 180 | 2017-10-23 | 2023-02-02 |
| Progesterone to Enhance the Efficacy and Success of Expectantly Managed Preterm Severe/Superimposed Preeclampsia 17 OHPC - Pregnancy, Preeclampsia (PE) | Phase 2 | Recruiting | University of Mississippi Medical Center | 60 | 2017-05-22 | 2026-05-01 |
| Safety and Pharmacokinetics of Dolutegravir in Pregnant HIV Mothers and Their Neonates: A Pilot Study Dolutegravir 50mg od, Standard of Care - HIV, Pregnancy | Phase 2 / Phase 3 | Completed | University of Liverpool | 60 | 2017-03-14 | 2025-09-04 |
| Evaluation of the Efficacy of Citrulline Supplementation on the Delay of Delivery for Women Hospitalized for Pre-eclampsia (CITRUPE) Citrulline, Placebo - Pre-eclampsia, Pregnancy | Phase 2 / Phase 3 | Completed | Nantes University Hospital | 116 | 2017-02-20 | 2026-09-14 |
| Can Ibuprofen Delay Ovulation in Natural Cycle-IVF? Ibuprofen - Ovulation, Ovulation Inhibition | Phase 2 | Completed | Insel Gruppe AG, University Hospital Bern | 51 | 2016-01-01 | 2024-11-19 |
| Thrombocytopenia in Gestational Period Dexamethasone - Immune Thrombocytopenia, Pregnancy | Phase 2 / Phase 3 | Unknown | Peking University People's Hospital | 70 | 2016-01-01 | 2016-04-26 |
| Antiretroviral Regimens Containing Raltegravir for Prophylaxis of Mother-to-child-transmission of HIV Infection Raltegravir, Lopinavir/Ritonavir - HIV, Pregnancy | Phase 2 / Phase 3 | Terminated | Fundação Bahiana de Infectologia | 33 | 2015-06-01 | 2024-10-15 |
| Biomarker Feedback to Motivate Cessation in Pregnancy Biomarker feedback (phone based smoking cessation counseling), Control condition (phone based smoking cessation counseling) - Nicotine Dependence, Pregnancy | Phase 2 | Completed | Mayo Clinic | 60 | 2015-03-01 | 2017-12-19 |
Showing 20 of 58. Sign in to see all of them.
Pre-Eclampsia (4) · Behavior (3) · HIV Infections (3) · Breast Feeding (2) · Diabetes Mellitus, Type 2 (2) · Hypotension (2) · Obesity (2) · Smoking Cessation (2) · Substance-Related Disorders (2) · Acquired Immunodeficiency Syndrome (1) · Agnosia (1) · Depression (1) · Diabetes, Gestational (1) · Disease Progression (1) · Fetal Membranes, Premature Rupture (1)
Urogenital Diseases (14) · Infections (10) · Female Urogenital Diseases and Pregnancy Complications (8) · Pathological Conditions, Signs and Symptoms (8) · Communicable Diseases (7) · Genital Diseases (7) · Pregnancy Complications (7) · Virus Diseases (7) · Behavior (6) · Blood-Borne Infections (6) · Immune System Diseases (6) · RNA Virus Infections (6) · Immunologic Deficiency Syndromes (5) · Lentivirus Infections (5) · Nutritional and Metabolic Diseases (5)
Misoprostol (4) · Tenofovir (3) · Insulin (2) · Lopinavir (2) · Metformin (2) · Raltegravir Potassium (2) · 17-alpha-Hydroxyprogesterone (1) · Activities of Daily Living (1) · Acupuncture Therapy (1) · Biological Products (1) · Blood Specimen Collection (1) · BufferGel (1) · Bupivacaine (1) · Bupropion (1) · Cabergoline (1)
University of North Carolina, Chapel Hill (4) · Gynuity Health Projects (2) · Mansoura University (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · ANRS, Emerging Infectious Diseases (1) · Auerbach Hematology Oncology Associates P C (1) · Centers for Disease Control and Prevention (1) · Dilafor AB (1) · Dow University of Health Sciences (1) · Edgard Costa de Vilhena (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · French National Agency for Research on AIDS and Viral Hepatitis (1) · Fundação Bahiana de Infectologia (1) · Gonabad University of Medical Sciences (1) · HIV Prevention Trials Network (1)
United States (24) · South Africa (4) · Brazil (2) · Canada (2) · Egypt (2) · France (2) · Mexico (2) · Uganda (2) · Zambia (2) · Zimbabwe (2) · Australia (1) · Bangladesh (1) · Bolivia (1) · Cambodia (1) · China (1)
Abdullah Baqui, MBBS (1) · Adalberto Sanchez, PhD (1) · Albert Moore, MD (1) · Allan M Cyna, FRCA (1) · Ana A Baumann, PhD (1) · Ana C Plata, MSc (1) · Ashley Hickman, MD (1) · Asnat Walfisch, MD (1) · Babbette LaMarca, PhD (1) · Benjamin Chi, MD, MSc (1) · Benjamin H Chi, MD (1) · Beverly Winikoff, MD, MPH (1) · Carlo Contini, Professor (1) · Carlos Brites, MD, PhD (1) · Christi A Patten, PhD (1)
PMID 16966110, PMID 17766603, PMID 17997151, PMID 18520682, PMID 18987623, PMID 19104016, PMID 19307941, PMID 19886836, PMID 19919718, PMID 20842042, PMID 21091415, PMID 21199294, PMID 21861025, PMID 21928117, PMID 22761006, PMID 23096052, PMID 23587190, PMID 23864647, PMID 23867137, PMID 23998516, PMID 24652353, PMID 24704179, PMID 24937546, PMID 25225008, PMID 25874236, PMID 26066384, PMID 26592857, PMID 27004997, PMID 27079291, PMID 27506771, PMID 27872513, PMID 28660118, PMID 28739199, PMID 28741272, PMID 28752805, PMID 30831103, PMID 31539371, PMID 32120420, PMID 32661003, PMID 33015104, PMID 33346335, PMID 36996264, PMID 37230961, PMID 38462256, PMID 39077939, PMID 39638148
K23HL106231 (1), R01AI157859 (1), R01DA019180 (1), R01HD096796 (1), R21HD105101 (1), U10HD047905 (1), UM1AI068619 (1)