9 completed, 4 unknown, 1 terminated. 10 Not applicable, 3 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 6, Unknown 4 |
| Phase 4 | 3 | Completed 3 |
| Phase 2 | 1 | Terminated 1 |
Follow Post Inflammatory Hyperpigmentation: new trials by email Literature Review of Post Inflammatory Hyperpigmentation trials Research Report on Post Inflammatory Hyperpigmentation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Novel Regimen for Treatment and Prevention of Post-Inflammatory Hyperpigmentation in Skin of Color Pigment Balancing Peel, Discoloration Defense Serum, LHA Cleansing Gel - Post Inflammatory Hyperpigmentation | Not applicable | Completed | Narrows Institute for Biomedical Research | 10 | 2025-02-28 | 2025-11-24 |
| Evaluation of the Safety and Tolerability of a Brightening Treatment Paired With a Skincare Regimen Brightening Treatment - Hyperpigmentation, Skin Ageing | Not applicable | Completed | Revision Skincare | 11 | 2024-10-07 | 2026-06-05 |
| Interventional, Monocentric, Double-blind Randomized Category 2b Study Evaluating the Evaluation of the Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post -Inflammatory Hyperpigmentation (Pih)) on the Face CRYONOVE (EC14_4osc), CRYONOVE (EC05osc) - Lentigo, Solar Lentigo | Not applicable | Completed | Cryonove Pharma | 30 | 2024-09-16 | 2024-12-24 |
| Evaluation of the Tolerance (Main Objective) and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-inflammatory Hyperpigmentation) on the Face CRYONOVE (EC14_4osc), CRYONOVE (EC+05_1osc), CRYONOVE (EC+05_2osc) - Lentigo, Solar Lentigo | Not applicable | Unknown | Cryonove Pharma | 45 | 2024-04-01 | 2024-04-17 |
| Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-Inflammatory Hyperpigmentation) Condition 1 : Prototypes (816-v1) every weeks, Condition 2 : Prototypes (816-v1) every two weeks - Solar Lentigo, Senile Lentigo | Not applicable | Unknown | Cryonove Pharma | 80 | 2023-06-10 | 2023-06-01 |
| LiftActiv B3 in Post Inflammatory Hyperpigmentation (PIHP) Liftactiv B3, Sunscreen - Acne, Post Inflammatory Hyperpigmentation | Phase 2 | Terminated | University of Miami | 13 | 2022-03-22 | 2024-04-03 |
| Tazarotene 0.045% Lotion for Treating PIE and PIH in Subjects With Acne Tazarotene 0.045% Lotion - Acne Vulgaris, Post Inflammatory Hyperpigmentation | Phase 4 | Completed | Dr. Emmy Graber | 20 | 2021-02-01 | 2023-01-30 |
| Nanofat on Wound Healing and Scar Formation Nanofat injection - Scars, Delayed Wound Healing | Not applicable | Unknown | Universitair Ziekenhuis Brussel | 15 | 2019-03-01 | 2019-02-21 |
| Tranexamic Acid vs Fractional CO2 Laser in Post-acne Hyperpigmentation Tranexamic Acid, Fractional CO2 laser - Post Inflammatory Hyperpigmentation | Not applicable | Unknown | Cairo University | 25 | 2018-12-01 | 2018-12-05 |
| The Use of Onexton in Moderate Acne Vulgaris for Patients With Skin of Color ONEXTON Topical Gel - Acne Vulgaris, Post Inflammatory Hyperpigmentation | Phase 4 | Completed | Derm Research, PLLC | 21 | 2017-07-28 | 2019-04-02 |
| Effectiveness of Epidermal Growth Factor-containing Ointment on the Solar Lentigines epidermal growth factor (EGF)-containing ointment, Vehicle ointment, Q-swithced (QS) 532-nm Nd:yttrium aluminum garnet (YAG) laser - Epidermal Growth Factor, Nd-yttrium Aluminum Garnet Laser | Not applicable | Completed | Hallym University Kangnam Sacred Heart Hospital | 40 | 2017-07-20 | 2021-01-11 |
| The Efficacy of Bakuchiol in Treating PIH Bakuchiol, Vehicle - Post Inflammatory Hyperpigmentation | Not applicable | Completed | Henry Ford Health System | 22 | 2016-02-22 | 2025-02-19 |
| Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser topical 0.05% Clobetasol propionate ointment, Q switched Nd:YAG laser 532 nm - Lentigines, Post Inflammatory Hyperpigmentation | Not applicable | Completed | Mahidol University | 21 | 2015-02-01 | 2016-06-01 |
| Efficacy and Safety Study of Finacea to Treat Acne Vulgaris and Post-Inflammatory Hyperpigmentation (PIH) Azelaic acid - Acne Vulgaris, Post Inflammatory Hyperpigmentation | Phase 4 | Completed | Derm Research, PLLC | 20 | 2009-12-01 | 2012-09-25 |
Hyperpigmentation (14) · Acne Vulgaris (4) · Lentigo (3) · Cicatrix (2) · Cicatrix, Hypertrophic (1) · Erythema (1) · Skin Diseases (1)
Pigmentation Disorders (14) · Skin and Connective Tissue Diseases (14) · Skin Diseases (13) · Acneiform Eruptions (4) · Sebaceous Gland Diseases (4) · Melanosis (3) · Fibrosis (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (1) · Skin Manifestations (1)
BRCA1 Protein (1) · Epidermal Growth Factor (1) · Lasers (1) · Long-Term Synaptic Depression (1) · Sunscreening Agents (1) · Tranexamic Acid (1) · azelaic acid (1) · bakuchiol (1) · tazarotene (1)
Cryonove Pharma (3) · Derm Research, PLLC (2) · Cairo University (1) · Dr. Emmy Graber (1) · Hallym University Kangnam Sacred Heart Hospital (1) · Henry Ford Health System (1) · Mahidol University (1) · Narrows Institute for Biomedical Research (1) · Revision Skincare (1) · Universitair Ziekenhuis Brussel (1) · University of Miami (1)
United States (7) · South Africa (2) · South Korea (1) · Thailand (1)
Beverley Summers, Pr (1) · Bo Young Chung, M.D., PhD (1) · Emmy Graber (1) · Iltefat Hamzavi, MD (1) · Jared Jagdeo, MD MS (1) · Leon H. Kircik, M.D. (1) · Moustapha Hamdi, MD,PhD (1) · Woraphong Manuskiatti, M.D. (1)
PMID 20981308, PMID 21384391, PMID 24292155, PMID 24854088, PMID 33668564, PMID 34414642, PMID 7963648