5 completed, 3 terminated, 1 recruiting, 1 unknown. 10 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 5, Terminated 3, Recruiting 1, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow Polymyalgia Rheumatica: new trials by email Literature Review of Polymyalgia Rheumatica trials Research Report on Polymyalgia Rheumatica
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty Methotrexate, Sulfasalazine, Hydroxychloroquine - Rheumatic Disease | Phase 2 | Recruiting | NYU Langone Health | 80 | 2025-12-12 | 2026-07-09 |
| A Trial of Prednisolone in Combination With SPI-62 or Placebo in Subjects With Polymyalgia Rheumatica (PMR) SPI-62, SPI-62 matched placebo, Prednisolone 10mg - Polymyalgia Rheumatica | Phase 2 | Completed | Sparrow Pharmaceuticals | 66 | 2022-07-22 | 2025-05-11 |
| A Study to Evaluate the Change in Disease State and Adverse Events in Adult Participants With Polymyalgia Rheumatica (PMR) Dependent on Glucocorticoid Treatment, Receiving Subcutaneous Injections of ABBV-154 ABBV-154, Placebo, Glucocorticoid - Polymyalgia Rheumatica | Phase 2 | Terminated | AbbVie | 181 | 2021-09-09 | 2024-10-15 |
| Tofacitinib as a GC Sparing Agent for Polymyalgia Rheumatica Tofacitinib 5 MG - Polymyalgia Rheumatica, Effect of Drug | Phase 2 | Completed | RenJi Hospital | 14 | 2021-01-01 | 2022-09-15 |
| Low-dose Interleukin-2 Treatment on Polymyalgia Rheumatica Interleukin-2 - Polymyalgia Rheumatica | Phase 2 | Unknown | Peking University People's Hospital | 15 | 2019-08-31 | 2019-09-04 |
| Delayed Release Prednisone in PMR Delayed-Release (DR) Prednisone, Immediate Release (IR) Prednisone - Polymyalgia Rheumatica | Phase 2 | Terminated | Dinora, Inc. | 8 | 2016-02-01 | 2017-05-03 |
| Tocilizumab Effect iN pOlymyalgia Rheumatica TCZ - Polymyalgia Rheumatica | Phase 2 | Completed | University Hospital, Brest | 21 | 2012-07-01 | 2015-02-11 |
| Study of Tocilizumab to Treat Polymyalgia Rheumatica Tocilizumab - Polymyalgia Rheumatica (PMR) | Phase 2 | Completed | Hospital for Special Surgery, New York | 10 | 2011-04-01 | 2018-01-17 |
| A 3-arm Proof of Concept Study of AIN457, ACZ885 or Corticosteroids in Patients With Polymyalgia Rheumatica AIN457, ACZ885, Prednisone - Polymyalgia Rheumatica, Inflammatory Diseases | Phase 2 | Terminated | Novartis Pharmaceuticals | 16 | 2011-02-14 | 2021-09-17 |
| Timed Release Tablet Prednisone in Polymyalgia Rheumatica Timed Release Tablet Prednisone, Prednisolone - Polymyalgia Rheumatica | Phase 2 / Phase 3 | Completed | University Hospitals Bristol and Weston NHS Foundation Trust | 12 | 2009-10-01 | 2022-09-13 |
Rheumatic Diseases (2) · Arthritis, Juvenile (1) · Arthritis, Psoriatic (1) · Arthritis, Rheumatoid (1) · Dermatomyositis (1) · Giant Cell Arteritis (1) · Granulomatosis with Polyangiitis (1) · Lupus Erythematosus, Systemic (1) · Polymyositis (1) · Spondylarthritis (1) · Spondylitis, Ankylosing (1) · Vasculitis (1)
Connective Tissue Diseases (10) · Muscular Diseases (10) · Musculoskeletal Diseases (10) · Skin and Connective Tissue Diseases (10) · Rheumatic Diseases (8) · Ankylosis (1) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (1) · Arteritis (1) · Arthritis (1) · Autoimmune Diseases (1) · Autoimmune Diseases of the Nervous System (1) · Axial Spondyloarthritis (1) · Bone Diseases (1) · Brain Diseases (1) · Cardiovascular Diseases (1)
Prednisone (3) · Prednisolone (2) · canakinumab (2) · secukinumab (2) · tocilizumab (2) · tofacitinib (2) · Abatacept (1) · Adalimumab (1) · Azathioprine (1) · Certolizumab Pegol (1) · Cyclosporine (1) · Etanercept (1) · Glucocorticoids (1) · Hydroxychloroquine (1) · Infliximab (1)
AbbVie (1) · Dinora, Inc. (1) · Hospital for Special Surgery, New York (1) · NYU Langone Health (1) · Novartis Pharmaceuticals (1) · Peking University People's Hospital (1) · RenJi Hospital (1) · Sparrow Pharmaceuticals (1) · University Hospital, Brest (1) · University Hospitals Bristol and Weston NHS Foundation Trust (1)
United States (5) · Germany (3) · United Kingdom (3) · France (2) · Italy (2) · Poland (2) · Australia (1) · Austria (1) · Canada (1) · China (1) · Hungary (1) · Japan (1) · Netherlands (1) · New Zealand (1) · South Korea (1)
David Katz (1) · John R Kirwan, MBBS,MD,FRCP (1) · Jonathan Samuels, MD (1) · Robert F Spiera, MD (1) · Ting Li, MD (1)
PMID 24489611, PMID 26929219, PMID 30877202, PMID 33301930, PMID 36604153, PMID 39400109, PMID 518143, PMID 9009973