8 completed, 1 active not recruiting, 1 terminated. 10 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 8, Active not recruiting 1, Terminated 1 |
Follow Pleural Effusion, Malignant: new trials by email Literature Review of Pleural Effusion, Malignant trials Research Report on Pleural Effusion, Malignant
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase Ⅲ Clinical Study of Combined Cisplatin Versus Placebo Combined With Intracavitary Cisplatin Injection in the Treatment of Malignant Pleural Effusions ENDOSTAR，cisplatin, Placebo , cisplatin - Malignant Pleural Effusion | Phase 3 | Active not recruiting | Jiangsu Simcere Pharmaceutical Co., Ltd. | 290 | 2021-07-28 | 2026-01-02 |
| Efficacy of Iodopovidone Versus Talc in Palliative Malignant Pleural Effusion Iodopovidone solution, Talc - Malignant Pleural Effusion | Phase 3 | Completed | Chiang Mai University | 60 | 2015-11-01 | 2020-01-23 |
| Efficacy and Safety Study of Abnoba Viscum F 20mg in Malignant Pleural Effusion Patients Abnoba Viscum F 20mg - Malignant Pleural Effusion | Phase 3 | Completed | Abnoba Korea | 68 | 2011-01-01 | 2014-07-23 |
| Intrapleural Bevacizumab and Cisplatin Therapy for Malignant Pleural Effusion Caused by Non-small Cell Lung Cancer Bevacizumab, Cisplatin - Malignant Pleural Effusion | Phase 3 | Completed | Chinese PLA General Hospital | 72 | 2009-08-01 | 2015-03-25 |
| Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy Darbepoetin alfa, Placebo - Non-Small Cell Lung Cancer, Anemia | Phase 3 | Terminated | Amgen | 2549 | 2009-07-17 | 2022-11-30 |
| A Prospective, Randomized Controlled Trial for a Rapid Pleurodesis Protocol for the Management of Pleural Effusions Thoracoscopy and Pleurx, Thoracoscopy - Malignant Pleural Effusions | Phase 3 | Completed | Singapore General Hospital | 120 | 2008-09-01 | 2017-02-10 |
| Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant Mesothelioma talc, therapeutic thoracoscopy, therapeutic videothoracoscopy - Malignant Mesothelioma, Metastatic Cancer | Phase 3 | Completed | Papworth Hospital NHS Foundation Trust | 196 | 2003-09-01 | 2013-06-28 |
| Standard Chest Tube Compared With a Small Catheter in Treating Malignant Pleural Effusion in Patients With Cancer talc, dyspnea management - Metastatic Cancer, Pulmonary Complications | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 67 | 2002-05-01 | 2016-07-04 |
| Bleomycin, Doxycycline, or Talc in Treating Patients With Malignant Pleural Effusions bleomycin sulfate, doxycycline, talc - Metastatic Cancer | Phase 3 | Completed | Eastern Cooperative Oncology Group | 480 | 1997-01-10 | 2023-06-22 |
| Talc in Treating Patients With Malignant Pleural Effusion talc, Talc - Metastatic Cancer | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 501 | 1994-12-01 | 2016-06-28 |
Neoplasm Metastasis (4) · Carcinoma, Non-Small-Cell Lung (2) · Anemia (1) · Lung Neoplasms (1) · Mesothelioma, Malignant (1) · Neoplasms (1) · Pleural Effusion (1) · Solitary Fibrous Tumor, Pleural (1)
Neoplasms by Site (10) · Pleural Diseases (10) · Pleural Neoplasms (10) · Respiratory Tract Diseases (10) · Respiratory Tract Neoplasms (10) · Thoracic Neoplasms (10) · Neoplasms (9) · Pleural Effusion (9) · Neoplastic Processes (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Lung Diseases (3) · Bronchial Neoplasms (2) · Carcinoma, Bronchogenic (2) · Lung Neoplasms (2)
Talc (5) · Cisplatin (2) · Bevacizumab (1) · Bleomycin (1) · Darbepoetin alfa (1) · Doxycycline (1) · Povidone-Iodine (1) · Thoracoscopy (1) · viscum album peptide (1)
Alliance for Clinical Trials in Oncology (2) · Abnoba Korea (1) · Amgen (1) · Chiang Mai University (1) · Chinese PLA General Hospital (1) · Eastern Cooperative Oncology Group (1) · Jiangsu Simcere Pharmaceutical Co., Ltd. (1) · Papworth Hospital NHS Foundation Trust (1) · Singapore General Hospital (1)
China (3) · United States (3) · Canada (2) · South Korea (2) · United Kingdom (2) · Argentina (1) · Austria (1) · Belgium (1) · Brazil (1) · Bulgaria (1) · Chile (1) · Croatia (1) · Czechia (1) · Germany (1) · Greece (1)
Apichat Tantraworasin (1) · Devanand Anantham, FCCP (1) · Friedemann Schad, MD (1) · Jemi Olak, MD (1) · Jin Li, Doctor (1) · John C. Ruckdeschel, MD (1) · Kook Joo Na, MD (1) · Nan Du (1) · Randolph S. Marks, MD (1) · Robert Winter, MD (1) · Shukui Qin, Doctor (1) · Todd Demmy, MD (1) · Yeong Dae Kim, MD (1) · YongJik Lee, MD (1)
PMID 15764775, PMID 14973997, PMID 16478853, PMID 17567670, PMID 24942631
U10CA031946 (1), U10CA076001 (1)