145 completed, 23 unknown, 4 not yet recruiting, 3 recruiting. 61 Phase 3, 38 Phase 4, 24 Phase 2, 17 Phase 1, 15 Not applicable.
Follow Pertussis: new trials by email Literature Review of Pertussis trials Research Report on Pertussis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Study on Immunogenicity Persistence of Adsorbed 5-component Acellular Pertussis, Diphtheria and Tetanus Combined Vaccine Previously received the Tdcp vaccine at age 18 and older, Previously received the Tdcp vaccine at age 12-17, Previously received the Tdcp vaccine at age 6-11 - Diphtheria, Tetanus | Not yet recruiting | CanSino Biologics Inc. | 160 | 2026-10-15 | 2026-08-04 | |
| A Phase I/II Clinical Trial of the Diphtheria, Tetanus, Acellular Component Pertussis and Sabin Inactivated Poliomyelitis Vaccine Adsorbed Diphtheria, Tetanus, Acellular Component Pertussis and Sabin Inactivated Poliomyelitis Vaccine Adsorbed, Diphtheria, Tetanus and Acellular Component Pertussis Combined Vaccine, Diphtheria, Tetanus and Acellular Component Pertussis Combined Vaccine+Inactivated Poliomyelitis Vaccine Made From Sabin Strains - Diphtheria, Pertussis | Phase 1 / Phase 2 | Recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 380 | 2026-10-11 | 2026-10-23 |
| Study of BK1803 in Healthy Infants BK1803, GOBIK Aqueous Suspension Syringes, Bimmugen® Injection - Pertussis, Diphtheria | Phase 3 | Not yet recruiting | Tanabe Pharma Corporation | 344 | 2026-10-01 | 2026-08-28 |
| Maternal Immunization With Tetanus Toxoid, Reduced Diphtheria Toxoid, Reduced-dose (2 µg) Recombinant Pertussis Vaccine (TdaP2gen) and Its Effect on the Immune Response in Thai Infants up to 15-18 Months Old Maternal TdaP2gen vaccine, Infant Acellular Pertussis-containing Vaccine, Infant Whole-cell Pertussis-containing Vaccine - Pertussis, Diphtheria | Phase 4 | Not yet recruiting | Chiang Mai University | 320 | 2026-05-26 | 2026-06-02 |
| Phase I/II Clinical Trial of Diphtheria-Tetanus-Pertussis (Reduced Dose) Vaccine low-dose Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (Reduced Antigens Content), high-dose Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (Reduced Antigens Content), Tetanus, Diphtheria and Acellular Pertussis Vaccine - Tetanus, Diphtheria and Acellular Pertussis Vaccination, Tetanus | Phase 1 / Phase 2 | Not yet recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 660 | 2026-03-12 | 2026-02-18 |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series LBVD, Pentavalent vaccine and Inactivated Polio vaccine - Diphtheria, Tetanus | Phase 2 / Phase 3 | Active not recruiting | LG Chem | 1186 | 2025-05-30 | 2026-09-03 |
| 10-year Follow-up After a Single Dose Acellular Pertussis Vaccination Pertagen® vaccine, Adacel® vaccine - Pertussis | Phase 4 | Completed | Mahidol University | 90 | 2025-05-13 | 2026-10-08 |
| A Clinical Trials of Adsorbed Cell-free DPT Vaccine (Five-component) Tetanus, Reduced Diphtheria and Acellular Pertussis (Five Components) Combined Vaccine, Adsorbed (Tdcp)), 23-valent Pneumococcal Polysaccharide Vaccine (PPV23), Tdcp - Diphtheria, Tetanus | Phase 2 / Phase 3 | Completed | CanSino Biologics Inc. | 1820 | 2024-12-20 | 2026-08-26 |
| Study to Evaluate the Immunogenicity of LR20062 Compared to Control When Administered Intramuscularly in Healthy Infants At 2, 4, 6 Months of Age LR20062, DTaP-HepB-IPV-Hib vaccine - Diphtheria, Tetanus | Phase 2 | Unknown | LG Chem | 336 | 2024-10-02 | 2024-10-01 |
| Safety and Immunogenicity of DTaP-IPV/Hib Pentavalent Vaccine in Chinese 2-month-old Infants Different immunization regiments with DTaP-IPV/Hib Pentavalent Vaccine - Pertussis, Diphtheria | Not applicable | Unknown | Jiangsu Province Centers for Disease Control and Prevention | 785 | 2024-09-05 | 2024-09-20 |
| Phase I Clinical Trial of Diphtheria-Tetanus-acellular Pertussis Component Combined Vaccine DTacP (one-dose booster), DTacP (three-dose primary vaccination), DT (one-dose booster) - Diphtheria, Tetanus | Phase 1 | Recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 460 | 2023-12-23 | 2024-01-03 |
| Prevalence and Impact of Pertussis and RSV on Asthma Severity and Control PCR - Asthma, Pertussis | Unknown | Hospital Clinico Universitario de Santiago | 784 | 2023-12-21 | 2024-03-01 | |
| A Clinical Trial of Adsorbed Cell-free DPT Vaccine (5-component) (for People Aged 6 Years and Above) Tetanus, Reduced Diphtheria and Acellular Pertussis (Five Components) Combined Vaccine, Adsorbed (Aged 6 Years and Older) (Tdcp), 23-Valent Pneumococcal Polysaccharide Vaccine（PPV23）, Diphtheria and Tetanus Combined Vaccine, Adsorbed (DT) - Diphtheria, Tetanus | Phase 1 | Completed | CanSino Biologics Inc. | 180 | 2023-12-06 | 2026-08-07 |
| Knowledge of Pregnant Women Concerning Pertussis, Vaccination Against Pertussis and Cocooning Strategy Data collection - Pertussis | Unknown | Université de Reims Champagne-Ardenne | 500 | 2023-12-01 | 2023-11-07 | |
| Maternal Determinants of Infant Immunity to Pertussis Triaxis® (Pertussis-containing vaccine), Vaxelis® (Pertussis-containing vaccine) - Vaccination; Infection, Maternal-Fetal Relations | Phase 4 | Completed | Centre Hospitalier Universitaire Saint Pierre | 200 | 2023-09-12 | 2026-01-13 |
| A Study to Evaluate Safety and Immunogenicity of APV006 in Healthy Adults DTaP-HepB-IPV-Hib vaccine - Diphtheria, Tetanus | Phase 1 | Unknown | LG Chem | 42 | 2023-07-17 | 2023-07-19 |
| Pathogenic Bordetella Rapid Detection Detection pathogenic pertussis by cross primer constant temperature amplification (CPA) and drug resistant genes of erythromycin by CRISPR technology - Pertussis | Withdrawn | Children's Hospital of Fudan University | 2022-07-01 | 2022-09-14 | ||
| Safety and Immunogenicity of 2 Doses Versus 1 Dose of Acellular Pertussis Vaccines Containing Genetically-detoxified Pertussis Toxin in Young Adults Previously Primed With Acellular Pertussis Vaccines Pertagen®, Revaxis® - Pertussis, Vaccine-Preventable Diseases | Phase 2 / Phase 3 | Unknown | University Hospital, Geneva | 100 | 2022-02-07 | 2022-01-18 |
| Establishing a Controlled Human Infection Model of Bordetella Pertussis Bordetella pertussis D420 - Pertussis | Phase 1 | Completed | Dalhousie University | 79 | 2022-01-28 | 2026-09-03 |
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Whooping Cough (180) · Diphtheria (118) · Tetanus (118) · Poliomyelitis (62) · Haemophilus Infections (56) · Hepatitis B (52) · Measles (9) · Influenza, Human (7) · Infections (6) · Communicable Diseases (5) · Meningitis (5) · Meningococcal Infections (4) · Vaccine-Preventable Diseases (4) · Bacterial Infections (3) · Immune System Diseases (3)
Bacterial Infections and Mycoses (180) · Bordetella Infections (179) · Gram-Negative Bacterial Infections (179) · Respiratory Tract Diseases (179) · Respiratory Tract Infections (178) · Bacterial Infections (177) · Infections (174) · Gram-Positive Bacterial Infections (125) · Actinomycetales Infections (119) · Clostridium Infections (118) · Corynebacterium Infections (118) · Virus Diseases (87) · RNA Virus Infections (73) · Nervous System Diseases (68) · Neuroinflammatory Diseases (67)
Tetanus Toxoid (38) · adacel (26) · Diphtheria-Tetanus-acellular Pertussis Vaccines (16) · Pentavac (12) · DTaP-IPV-HB-PRP-T vaccine (9) · Boostrix (8) · Blood Specimen Collection (7) · Data Collection (7) · Poliovirus Vaccine, Inactivated (7) · pentacel (7) · Diphtheria-Tetanus Vaccine (6) · Hepatitis B Vaccines (6) · Vaccines, Combined (6) · diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (6) · Poliovirus Vaccine, Oral (5)
Sanofi Pasteur, a Sanofi Company (51) · Sanofi (17) · GlaxoSmithKline (11) · National Institute of Allergy and Infectious Diseases (NIAID) (10) · LG Chem (7) · Mahidol University (5) · CanSino Biologics Inc. (4) · St George's, University of London (4) · Crucell Holland BV (3) · Institute of Medical Biology, Chinese Academy of Medical Sciences (3) · Merck Sharp & Dohme LLC (3) · Novartis Vaccines (3) · Shantha Biotechnics Limited (3) · Tanabe Pharma Corporation (3) · Universiteit Antwerpen (3)
United States (38) · China (16) · Canada (12) · Thailand (12) · Philippines (10) · South Korea (9) · Belgium (6) · Japan (6) · India (5) · Sweden (5) · United Kingdom (5) · Vietnam (5) · Germany (4) · Mexico (4) · France (3)
Raman Rao, MD (3) · Elke Leuridan, MD, PhD (2) · Eva Netterlid (2) · Lingwei Wang (2) · Maria RZ Capeding, MD (2) · Nabil Al-Tawil, MD, PhD (2) · Punnee Pitisuttithum, MD (2) · Aaron Sibley, MD (1) · Abdul M Kazi, MBBS,MPH (1) · Alison Connor, PhD (1)
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