3 terminated, 1 completed, 1 unknown. 5 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Terminated 3, Completed 1, Unknown 1 |
Follow Persistent Fetal Circulation Syndrome: new trials by email Literature Review of Persistent Fetal Circulation Syndrome trials Research Report on Persistent Fetal Circulation Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn placebo, iv sildenafil - Pulmonary Hypertension, Familial Persistent, of the Newborn | Phase 3 | Completed | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 59 | 2013-08-05 | 2021-08-16 |
| Persistent Pulmonary Hypertension of the Newborn Bosentan, Matching placebo - Persistent Pulmonary Hypertension of the Newborn | Phase 3 | Terminated | Actelion | 23 | 2011-12-01 | 2025-02-04 |
| Sildenofil in Persistent Pulmonary Hypertension in Newborns Sildenafil, diluent - Persistent Fetal Circulation Syndrome | Phase 3 | Unknown | Hamad Medical Corporation | 100 | 2011-11-01 | 2012-09-25 |
| Early Inhaled Nitric Oxide for Respiratory Failure in Newborns Inhaled Nitric Oxide, Standard iNO therapy - Infant, Newborn, Hypertension, Pulmonary | Phase 3 | Terminated | NICHD Neonatal Research Network | 302 | 1998-08-01 | 2017-09-26 |
| Inhaled Nitric Oxide Study for Respiratory Failure in Newborns Inhaled nitric oxide, Placebo - Infant, Newborn, Hypertension, Pulmonary | Phase 3 | Terminated | NICHD Neonatal Research Network | 235 | 1995-10-01 | 2017-09-26 |
Hypertension, Pulmonary (2) · Meconium Aspiration Syndrome (2) · Methemoglobinemia (2) · Pneumonia, Aspiration (2) · Respiratory Distress Syndrome (2) · Respiratory Distress Syndrome, Newborn (2) · Respiratory Insufficiency (2)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Infant, Newborn, Diseases (5) · Lung Diseases (5) · Respiratory Tract Diseases (5) · Hypertension, Pulmonary (3) · Cardiovascular Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Fetal Diseases (2) · Hematologic Diseases (2) · Hemic and Lymphatic Diseases (2) · Hypertension (2) · Infant, Premature, Diseases (2) · Infections (2) · Lung Injury (2) · Pneumonia (2)
Sildenafil Citrate (2) · Bosentan (1) · Saline Solution (1)
NICHD Neonatal Research Network (2) · Actelion (1) · Hamad Medical Corporation (1) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (1)
United States (3) · Canada (2) · Belgium (1) · Denmark (1) · France (1) · Germany (1) · Italy (1) · Netherlands (1) · Norway (1) · Qatar (1) · Spain (1) · Sweden (1) · United Kingdom (1)
Avroy A. Fanaroff, MD (2) · Edward F. Donovan, MD (2) · Lu-Ann Papile, MD (2) · Mary Wearden, MD (2) · Richard A. Ehrenkranz, MD (2) · Seetha Shankaran, MD (2) · Sheldon B. Korones, MD (2) · A. Johnston, MD (1) · A. Solimano, MD (1) · Abbot R. Laptook, MD (1) · Barbara J. Stoll, MD (1) · C. Fajardo, MD (1) · Carlos Fajardo, MD (1) · Charles R. Bauer, MD (1) · David K. Stevenson, MD (1)
PMID 10802492, PMID 11416871, PMID 14510322, PMID 14993550, PMID 17307536, PMID 27502103, PMID 34052232, PMID 9036320, PMID 9190553
M01RR000070 (2), M01RR000750 (2), M01RR000997 (2), M01RR001032 (2), M01RR006022 (2), M01RR008084 (2), U01HD019897 (2), U10HD021364 (2), U10HD021373 (2), U10HD021385 (2), U10HD021397 (2), U10HD021415 (2), U10HD027853 (2), U10HD027856 (2), U10HD027871 (2)