14 completed, 13 recruiting, 6 not yet recruiting, 5 active not recruiting. 27 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 3, 1 Phase 4.
Follow PCOS (Polycystic Ovary Syndrome): new trials by email Literature Review of PCOS (Polycystic Ovary Syndrome) trials Research Report on PCOS (Polycystic Ovary Syndrome)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Symptoms of Polycystic Ovarian Syndrome Ameliorated by Keto-Adaptation Pilot Ketogenic diet, Exogenous Ketone Supplement - PCOS (Polycystic Ovary Syndrome) | Not applicable | Recruiting | Ohio State University | 40 | 2026-12-01 | 2026-05-08 |
| PMOS in OSA Pilot Study Continuous Positive Airway Pressure (CPAP) - PCOS, PCOS (Polycystic Ovary Syndrome) | Not applicable | Recruiting | University of Chicago | 10 | 2026-10-01 | 2026-10-13 |
| Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS) Beef+ - PCOS (Polycystic Ovary Syndrome), Obese Adolescents | Not applicable | Recruiting | Texas A&M University | 36 | 2026-09-01 | 2026-08-21 |
| Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOS Metformin, İnositol, Folic Acid - PCOS (Polycystic Ovary Syndrome), Insulin Resistance | Not applicable | Recruiting | Dicle University | 90 | 2026-08-13 | 2026-10-16 |
| Assessment of Metabolic Changes in Response to Glcuose Intake in Women With Polyendocrine Metabolic Ovarian Syndrome (PMOS) Oral Clucose Tolerance Test (oGTT) - PCOS (Polycystic Ovary Syndrome), Insulinemic Response | Not applicable | Not yet recruiting | University of Zurich | 40 | 2026-08-01 | 2026-07-07 |
| Observational Study on the Causal Architecture of Polycystic Ovary Syndrome (PCOS) No intervention - observational data collection only - Polycystic Ovary Syndrome, Polycystic Ovary Syndrome (PCOS) | Not yet recruiting | AnnieGuard Corp. | 100 | 2026-06-01 | 2026-06-03 | |
| Health-Related Quality of Life and Metabolic Outcomes in PCOS Intervention Group - PCOS (Polycystic Ovary Syndrome) | Not applicable | Active not recruiting | The Cleveland Clinic | 40 | 2026-06-01 | 2026-10-08 |
| Efficacy of a GLP-1/FGF21 Dual Agonist for Treating PCOS GLP-1/FGF21 dual agonist (HEC88473) - PCOS (Polycystic Ovary Syndrome) | Phase 2 | Recruiting | Shanghai Zhongshan Hospital | 30 | 2026-06-01 | 2026-05-29 |
| MeDiApp-PCOS: A Mobile Mediterranean Diet App for Women With Polycystic Ovary Syndrome Mobile Application-Based Personalized Mediterranean Diet and Lifestyle Intervention, Standard Lifestyle Advice for PCOS - PCOS (Polycystic Ovary Syndrome) | Not applicable | Not yet recruiting | Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health | 60 | 2026-05-13 | 2026-06-03 |
| The Aim of This Study is to Gain Insight Into the Occurrence of Irritable Bowel Symptoms During Ovarian Stimulation in Individuals With PCOS and in Women Who Wish to Freeze Their Eggs. This Study Uses Questionnaires. questionnaires - PCOS (Polycystic Ovary Syndrome) | Not applicable | Not yet recruiting | Universitair Ziekenhuis Brussel | 120 | 2026-04-20 | 2026-04-16 |
| The Physical and Mental Impact of ART: IVM vs Conventional Ovarian Stimulation Questionnaires - PCOS (Polycystic Ovary Syndrome) | Not applicable | Not yet recruiting | Universitair Ziekenhuis Brussel | 84 | 2026-01-01 | 2025-12-10 |
| The Effects of the Mediterranean Diet and Synbiotics in Polycystic Ovary Syndrome Synbiotic Supplement, Placebo - PCOS (Polycystic Ovary Syndrome) | Not applicable | Not yet recruiting | Atlas University | 32 | 2025-12-20 | 2026-01-15 |
| ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence ActiveGirls Physical Activity Program (Full), ActiveGirls Physical Activity Program (Delayed Lower Intensity) - PCOS (Polycystic Ovary Syndrome), Puberty | Not applicable | Recruiting | Massachusetts General Hospital | 40 | 2025-11-24 | 2026-03-19 |
| Transcriptomic Profiling of Cumulus Cells From CAPA-IVM PCOS (Polycystic Ovary Syndrome), Cumulus Cell | Recruiting | Mỹ Đức Hospital | 10 | 2025-10-16 | 2025-11-21 | |
| Myo-Inositol and Folic Acid for Improving Inflammation in Polycystic Ovary Syndrome myo-inositol 2000 gm + folic acid 200 mcg - Inflammation Biomarkers, Poly Cystic Ovary Syndrome | Not applicable | Active not recruiting | Khyber Medical University Peshawar | 50 | 2025-10-11 | 2026-09-15 |
| Letrozole Extended vs Traditional Therapy for Ovulation Induction in Women With PCOS (PROLEx-PCOS) Traditional Letrozole Therapy, Extended Letrozole Therapy - PCOS (Polycystic Ovary Syndrome), Infertility | Not applicable | Recruiting | GABRIEL MONTEIRO PINHEIRO | 20 | 2025-09-01 | 2025-11-28 |
| Anxiety and Depression in Adolescent PCOS Adolescent PCOS group receiving oral contraceptives - PCOS (Polycystic Ovary Syndrome) | Not applicable | Completed | Ege University | 42 | 2025-08-17 | 2026-03-25 |
| Feasibility Effects of a Low-GI, High-fibre Diet in PCOS: a Prospective Cohort Study in Remote Yunnan low glycemic index-high fiber - PCOS (Polycystic Ovary Syndrome) | Recruiting | Shanghai First Maternity and Infant Hospital | 56 | 2025-08-10 | 2026-02-23 | |
| Clinical Research Cohort for Polycystic Ovary Syndrome PCOS (Polycystic Ovary Syndrome) | Active not recruiting | Guangdong Women and Children Hospital | 420 | 2025-07-28 | 2026-07-31 | |
| Effects of Folic Acid and Vitamin E on Hormones in Polycystic Ovary Syndrome Vitamin E 400, Folic Acid 5 Mg Oral Tablet - PCOS (Polycystic Ovary Syndrome) | Not applicable | Completed | Al-Mustansiriyah University | 207 | 2025-07-01 | 2026-07-23 |
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Polycystic Ovary Syndrome (40) · Insulin Resistance (5) · Obesity (3) · Overweight (3) · Infertility (2) · Menstruation Disturbances (2) · Metabolic Syndrome (2) · Amenorrhea (1) · Anovulation (1) · Anxiety Disorders (1) · Depression (1) · Hirsutism (1) · Hyperandrogenism (1) · Infertility, Female (1) · Inflammation (1)
Adnexal Diseases (40) · Cysts (40) · Endocrine System Diseases (40) · Female Urogenital Diseases (40) · Female Urogenital Diseases and Pregnancy Complications (40) · Genital Diseases (40) · Genital Diseases, Female (40) · Gonadal Disorders (40) · Neoplasms (40) · Ovarian Cysts (40) · Ovarian Diseases (40) · Urogenital Diseases (40) · Nutritional and Metabolic Diseases (9) · Pathological Conditions, Signs and Symptoms (7) · Body Weight (5)
Inositol (4) · Folic Acid (3) · Metformin (3) · Letrozole (2) · Surveys and Questionnaires (2) · drospirenone and ethinyl estradiol combination (2) · Cabergoline (1) · Caloric Restriction (1) · Continuous Positive Airway Pressure (1) · Diet (1) · Diet, Carbohydrate-Restricted (1) · Diet, Ketogenic (1) · Diet, Mediterranean (1) · Diosgenin (1) · Docosahexaenoic Acids (1)
Mst.Sumyara Khatun (3) · Guangdong Women and Children Hospital (2) · Jagiellonian University (2) · Lo.Li.Pharma s.r.l (2) · Mỹ Đức Hospital (2) · Universitair Ziekenhuis Brussel (2) · Ahmed Saad (1) · Al-Azhar University (1) · Al-Kindy College of Medicine (1) · Al-Mustansiriyah University (1) · AnnieGuard Corp. (1) · Atlas University (1) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1) · Betül Gümüş (1) · Colorado Center for Reproductive Medicine (1)
China (6) · United States (6) · Bangladesh (4) · Turkey (Türkiye) (3) · Egypt (2) · Iraq (2) · Pakistan (2) · Poland (2) · Vietnam (2) · Brazil (1) · Georgia (1) · Indonesia (1) · Italy (1) · Jordan (1) · Russia (1)
Shakeela Ishrat, FCPS (2) · Dr Mohsin Shah, PhD (1) · Dr Muzna Atif, Mphil (1) · El-Kotb Hasan El-Kotb El-Saeidy, Professor (1) · Gabriel M Pinheiro, MD (1) · Harth Mohamed Kamber, FICMS (Uro.) (1) · Heidi K Vanden Brink, PhD, MSc, RDMS (1) · Kamal Al-Jawdah, MBChB, MRCS, FIBMS (1) · Katherine Ann R Miller, Medical student (1) · Madison Kackley, PhD (1) · Maria Amin (1)
PMID 24362411, PMID 24563180, PMID 24601829, PMID 25885106, PMID 26613823, PMID 28834553, PMID 29100822, PMID 29703793, PMID 30614289, PMID 31229399, PMID 32442310, PMID 34455568, PMID 34732660, PMID 35774693, PMID 35829765, PMID 35951627, PMID 36060969, PMID 37098539
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