37 completed, 18 unknown, 8 recruiting, 5 not yet recruiting. 36 Not applicable, 6 Phase 4, 5 Phase 3, 3 Phase 2, 1 Early Phase 1.
Follow Pancreatitis, Acute Necrotizing: new trials by email Literature Review of Pancreatitis, Acute Necrotizing trials Research Report on Pancreatitis, Acute Necrotizing
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Necrosectomy With Cryotechnology for Accelerated Removal Cryotechnology Necrosectomy Procedure - Pancreatic Necrosis, Acute Pancreatitis | Not applicable | Recruiting | Christopher C. Thompson, MD, MSc | 20 | 2026-12-01 | 2026-06-25 |
| Surgical vs Endoscopic Resection of Walled Off Pancreatic Necrosis Using the Powered Endoscopic Debridement System Direct Endoscopic Necrosectomy with Powered Endoscopic Debridement, Transgastric Surgical Necrosectomy - Pancreatic Necrosis, Pancreatitis | Not applicable | Withdrawn | Stanford University | 2026-12-01 | 2026-04-24 | |
| Pancreatic Enzyme Replacement in Acute Necrotizing Pancreatitis Pancreatic enzyme capsules, Placebo - Acute Necrotizing Pancreatitis, Pancreatic Exocrine Insufficiency | Phase 3 | Recruiting | Asian Institute of Gastroenterology, India | 140 | 2026-04-10 | 2026-05-05 |
| Integrating Plasma Metagenomics and Host Response for Accurate Diagnosis of Infected Pancreatic Necrosis in a Prospective Multicenter Cohort of Acute Necrotizing Pancreatitis Acute Necrotizing Pancreatitis, Infected Pancreatic Necrosis | Not yet recruiting | Xiangya Hospital of Central South University | 200 | 2026-01-30 | 2026-01-08 | |
| Strategic Timing of Endoscopic Interventions in Infected Necrotizing Pancreatitis EUS-guided transluminal drainage of necrotic collection - Pancreatitis, Acute Necrotizing | Not applicable | Recruiting | Orlando Health, Inc. | 104 | 2026-01-28 | 2026-02-12 |
| Effectiveness of Endorotor PED® System Versus Conventional Endoscopic Techniques for the Management of Walled-off Pancreatic Necrosis in Acute Necrotizing Pancreatitis: Randomized Single-blinded Controlled Superiority Trial and Cost-utility Analysis Endorotor Group, Conventional group - Acute Necrotizing Pancreatitis | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 64 | 2026-01-20 | 2026-01-30 |
| Organ Dysfunction Changes in Acute Necrotizing Pancreatitis Patients With Sepsis Following Open Necrosectomy Necrotizing Pancreatitis patients' organdysfunction progression - Necrotizing Pancreatitis | Not yet recruiting | West China Hospital | 700 | 2025-10-05 | 2025-10-01 | |
| PERT in Acute Necrotizing Pancreatitis Pancreatic Enzyme Replacement Therapy, Placebo - Acute Pancreatitis Necrotizing, Nutrition Assessment | Phase 3 | Not yet recruiting | Asian Institute of Gastroenterology, India | 188 | 2025-10-01 | 2025-10-08 |
| Endoscopic Pancreatic Duct Stent Placement Versus Conventional Approach in the Treatment of Early Phase Acute Pancreatitis Endoscopic pancreatic duct stent placement, Conventional treatment of acute pancreatitis in early phase - Acute Pancreatitis (AP) | Not applicable | Not yet recruiting | Almazov National Medical Research Centre | 200 | 2025-09-01 | 2025-07-30 |
| Encapsulation-oriented vs. Timing-oriented Strategies for Necrotizing Pancreatitis The timing of endoscopic intervention for necrotizing pancreatitis is determined based on the degree of encapsulation, EUS-guided drainage based on the interval from the onset of acute pancreatitis - Walled Off Necrosis, Pancreatitis | Not applicable | Not yet recruiting | Tokyo University | 224 | 2025-08-05 | 2025-08-06 |
| A Study to Evaluate Splenectomy on Debridement for Acute Necrotizing Pancreatitis With Pancreatic Sinistral Portal Hypertension Splenectomy, Control - Acute Necrotizing Pancreatitis, Portal Hypertension | Not applicable | Recruiting | Zhejiang University | 66 | 2025-07-30 | 2025-07-23 |
| Etiology, Clinical Picture, Complications and Outcomes of Necrotizing Pancreatitis in Children. no intervention, observational study - Pancreatitis, Pancreatitis, Acute Necrotizing | Completed | Moscow Regional Research and Clinical Institute (MONIKI) | 102 | 2024-12-01 | 2025-02-20 | |
| The Study of the Natural Way of Development of External Pancreatic Fistulas in Children with Necrotizing Pancreatitis no intervention, observational study - Children, Pancreatic Fistula | Completed | Moscow Regional Research and Clinical Institute (MONIKI) | 26 | 2024-11-11 | 2025-02-20 | |
| Organ Dysfunction Change in Acute Necrotizing Pancreatitis Patients With Sepsis After Open Necrosectomy Necrotizing Pancreatitis patients' organ dysfunction progression - Necrotizing Pancreatitis | Recruiting | Chunling Jiang | 200 | 2024-06-15 | 2026-07-10 | |
| The Role of Double Pigtail Plastic Stents During Endoscopic Transmural Drainage of Pancreatic Fluid Collections. Introduction of double pigtail plastic stents through the LAMS during endoscopic transmural drainage of post-inflammatory pancreatic and peripancreatic fluid collections, Endoscopic transmural drainage of post-inflammatory pancreatic and peripancreatic fluid collections with use of LAMS only - Pancreatitis, Acute, Pancreatitis, Acute Necrotizing | Not applicable | Unknown | Nicolaus Copernicus University | 200 | 2024-01-01 | 2023-11-18 |
| CMV Reactivation in Acute Necrotizing Pancreatitis Acute Necrotizing Pancreatitis | Completed | Sanjay Gandhi Postgraduate Institute of Medical Sciences | 41 | 2023-06-05 | 2025-04-24 | |
| Tracking ENcapsulation of Pancreatic Collections in Acute Necrotizing Pancreatitis MRI - Acute Necrotizing Pancreatitis | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 100 | 2023-02-02 | 2023-02-08 | |
| Endoscopic Step-up Approach vs Aggressive Debridement of Large Pancreatic Walled-off Necrosis Direct Endoscopic Necrosectomy, Step-up Approach - Pancreatic Necrosis, Pancreatitis, Acute Necrotizing | Not applicable | Completed | Copenhagen University Hospital, Hvidovre | 25 | 2022-11-01 | 2025-02-13 |
| Immediate vs. On-demand Endoscopic Necrosectomy in Infected Walled-off Pancreatic Necrosis Endoscopic necrosectomy - Pancreatitis, Acute Necrotizing | Not applicable | Completed | University of Tehran | 50 | 2022-09-12 | 2025-10-14 |
| Immediate Necrosectomy vs. Step-up Approach for Walled-off Necrosis Immediate necrosectomy, Step-up approach - Pancreatic Fluid Collection, Walled-off Necrosis | Not applicable | Recruiting | Tokyo University | 70 | 2022-07-29 | 2022-10-27 |
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Pancreatitis (30) · Infections (4) · Pancreatic Pseudocyst (4) · Sepsis (4) · Critical Illness (2) · Disease (2) · Exocrine Pancreatic Insufficiency (2) · Intra-Abdominal Hypertension (2) · Pancreatic Diseases (2) · Pancreatic Fistula (2) · Pancreatitis, Alcoholic (2) · Pancreatitis, Chronic (2) · Abdominal Abscess (1) · Abdominal Injuries (1)
Digestive System Diseases (73) · Pancreatic Diseases (71) · Pancreatitis (43) · Pathological Conditions, Signs and Symptoms (14) · Pathologic Processes (12) · Neoplasms (6) · Cysts (5) · Disease Attributes (4) · Infections (4) · Inflammation (4) · Pancreatic Cyst (4) · Systemic Inflammatory Response Syndrome (4) · Alcohol-Induced Disorders (2) · Alcohol-Related Disorders (2) · Cardiovascular Diseases (2)
Observation (3) · Enteral Nutrition (2) · Laparotomy (2) · Meropenem (2) · Cefoperazone (1) · Cholangiopancreatography, Endoscopic Retrograde (1) · Conservative Treatment (1) · Cryotherapy (1) · Endoscopy (1) · Fluorouracil (1) · Metronidazole (1) · NovaMin (1) · Parenteral Nutrition (1) · Pentoxifylline (1) · Saline Solution (1)
AdventHealth (4) · Asian Institute of Gastroenterology, India (4) · Nantes University Hospital (3) · Orlando Health, Inc. (3) · Chinese University of Hong Kong (2) · First People's Hospital of Hangzhou (2) · Mayo Clinic (2) · Moscow Regional Research and Clinical Institute (MONIKI) (2) · Post Graduate Institute of Medical Education and Research, Chandigarh (2) · Sanjay Gandhi Postgraduate Institute of Medical Sciences (2) · Tianjin Nankai Hospital (2) · Tokyo University (2) · Wake Forest University Health Sciences (2) · Almazov National Medical Research Centre (1) · Assistance Publique - Hôpitaux de Paris (1)
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Ji Young Bang, MD MPH (3) · Leonid M Elin (2) · Mohan Gurjar, MD, PDCC (2) · Naiqiang Cui, Dr (2) · Rupjyoti Talukdar, MD (2) · Shyam Varadarajulu, MD (2) · Yousuke Nakai (2) · Adolfo Pisanu, Ph.D. (1) · Alireza Delavari, MD (1) · Amber Jones, DO, MPH (1) · Anthony Teoh (1) · Arvind Trindade, MD (1) · Atul Garg, MD (1) · Badri V Sigua, PhD (1)
PMID 20410514, PMID 37980922, PMID 17446837, PMID 19444515, PMID 19863956, PMID 21478061, PMID 23063972, PMID 24821463, PMID 25320523, PMID 25616312, PMID 26112745, PMID 26327134, PMID 27107634, PMID 28932088, PMID 29090245, PMID 29672416, PMID 29858393, PMID 29882517, PMID 30002773, PMID 30452918, PMID 30895583, PMID 31479658, PMID 31888751, PMID 32245906, PMID 32542577, PMID 32891214, PMID 32994239, PMID 33124700, PMID 33284467, PMID 33648879, PMID 34142315, PMID 34520686, PMID 34562471, PMID 35129503, PMID 35180798, PMID 35258123, PMID 35916981, PMID 35963665, PMID 36446550, PMID 36646148, PMID 36899292, PMID 36930105, PMID 37007743, PMID 37226252, PMID 38356344, PMID 38448625, PMID 38782021, PMID 40835042, PMID 40838259, PMID 41720198
2016 (1), R03DK061362 (1)