30 completed, 10 unknown, 5 recruiting, 5 terminated. 20 Not applicable, 19 Phase 2, 17 Phase 1, 3 Phase 4, 2 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MSA-01 in Multiple System Atrophy MSA-01, Placebo - Multiple System Atrophy (MSA) | Phase 3 | Recruiting | Tokyo University | 140 | 2026-02-09 | 2026-03-04 |
| Pilot Cluster RCT of an Indirect Contact Mental Health Literacy Program for 5th-Grade Students Indirect Contact, Standard MHL Lesson Only - Mental Health Literacy, Stigma (Social Distance) | Not applicable | Completed | Tokyo University | 128 | 2025-12-15 | 2026-07-22 |
| Scenario-Driven Virtual Reality Game for Dementia Education Program VR-Experienced + ASA VR Group, VR-Experienced + Standard Control Group, VR-Unexposed + ASA VR Group - Dementia | Not applicable | Enrolling by invitation | Universitas Airlangga | 200 | 2025-09-01 | 2025-11-20 |
| Encapsulation-oriented vs. Timing-oriented Strategies for Necrotizing Pancreatitis The timing of endoscopic intervention for necrotizing pancreatitis is determined based on the degree of encapsulation, EUS-guided drainage based on the interval from the onset of acute pancreatitis - Walled Off Necrosis, Pancreatitis | Not applicable | Not yet recruiting | Tokyo University | 224 | 2025-08-05 | 2025-08-06 |
| Enhancing Healthcare Students' Attitudes Toward Dementia Care Through Virtual Reality Education The VR dementia education group, The control group - Nursing Students, Education Program on Dementia | Not applicable | Completed | Universitas Airlangga | 200 | 2024-10-14 | 2025-11-19 |
| Early-stage Ovarian Clear Cell Carcinoma (OCCC) Patients at Risk of Recurrence FIGO Stage IC2 to II Ovarian Clear Cell Carcinoma | Unknown | National Taiwan University Hospital | 272 | 2024-03-15 | 2024-02-23 | |
| Education Program for Enhancing Healthcare Students' Attitudes Toward People Living With Dementia Health Education - Dementia | Not applicable | Completed | Universitas Airlangga | 400 | 2023-11-22 | 2025-11-19 |
| Impact of Nutrition, Sleep, and Physical Activity on Intellectual Function and Muscle Mass in Older Adults Fitbit wearing, with notification for sleep, activity and nutrition based fitbit data, Routine care - Cognition Disorders in Old Age, Cognitive Function | Not applicable | Completed | Tokyo University | 355 | 2023-11-08 | 2026-04-16 |
| WONDER-02 Trial: Plastic Stent vs. Lumen-apposing Metal Stent for Pancreatic Pseudocysts Plastic stent, LAMS - Pancreatic Fluid Collection, Pancreatitis | Not applicable | Not yet recruiting | Tokyo University | 80 | 2023-11-01 | 2023-11-15 |
| Management and Outcomes of Local Complications of Acute Pancreatitis and Postoperative Pancreatic Fistula Routine Clinical Management of Local Complications - Acute Pancreatitis, Pancreatic Fluid Collection | Recruiting | Tokyo University | 5000 | 2023-09-14 | 2026-10-07 | |
| Endoscopic Ultrasound-guided Rendezvous Versus Precut Papillotomy EUS-guided rendezvous, Early precut papillotomy group - Bile Duct Diseases | Not applicable | Recruiting | Chinese University of Hong Kong | 188 | 2023-09-05 | 2026-07-16 |
| Liver Injury After COVID-19 Vaccination Approved COVID-19 vaccine - Subjects After COVID-19 Vaccination | Completed | Humanity & Health Medical Group Limited | 379 | 2022-09-05 | 2025-03-24 | |
| Immediate Necrosectomy vs. Step-up Approach for Walled-off Necrosis Immediate necrosectomy, Step-up approach - Pancreatic Fluid Collection, Walled-off Necrosis | Not applicable | Recruiting | Tokyo University | 70 | 2022-07-29 | 2022-10-27 |
| Pembrolizumab Plus Olaparib in Patients With Recurrent Cervical Cancer Pembrolizumab, Olaparib - Cervical Cancer | Phase 2 | Unknown | Saitama Medical University International Medical Center | 28 | 2021-01-01 | 2022-08-09 |
| The Medical Management in Patients Exposed to Weapons of Mass Destruction Clinical interventions performed in acute settings (contaminated environment), Protection (clinician and patient), Decontamination (clinician and patient) - Chemical Injury, Chemicals; Intoxication | Enrolling by invitation | St. Justine's Hospital | 1000 | 2020-10-01 | 2025-10-01 | |
| Artificial Intelligence Versus Expert Endoscopists for Diagnosis of Gastric Cancer AI-based diagnosis, The expert endoscopists-based diagnosis - Gastric Cancer | Not applicable | Completed | Tokyo University | 500 | 2019-07-01 | 2019-11-20 |
| Teacher-led MHL Education in Japanese Preteens Short Mental Health Literacy Program (SMHLP) - Mental Health Literacy, Stigma of Mental Illness | Not applicable | Completed | Tokyo University | 1401 | 2019-06-01 | 2025-08-14 |
| The Overall Survival of Patients With Unresectable HCC in Real-life Hepatocellular Carcinoma | Recruiting | Humanity & Health Medical Group Limited | 5000 | 2018-07-16 | 2025-03-24 | |
| Efficacy of Peer Counseling, Social Engagement, and Combination Interventions in Improving Depressive Symptoms of Filipino Senior Citizens Community-based depression interventions - Depressive Symptoms | Not applicable | Completed | Tokyo University | 270 | 2018-04-01 | 2019-06-19 |
| A Study of the Efficacy and Safety of Rituximab in Participants With Systemic Sclerosis Double-Blind Placebo, Double-Blind Rituximab - Scleroderma, Systemic, Skin Sclerosis | Phase 2 / Phase 3 | Completed | Tokyo University | 56 | 2017-12-04 | 2020-02-18 |
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Carcinoma, Non-Small-Cell Lung (6) · Breast Neoplasms (3) · Dementia (3) · Depression (3) · Pancreatic Pseudocyst (3) · Pancreatitis (3) · Stomach Neoplasms (3) · Colonic Neoplasms (2) · Colorectal Neoplasms (2) · Esophageal Neoplasms (2) · Hypoxia-Ischemia, Brain (2) · Neoplasms (2) · Pancreatic Neoplasms (2) · Pancreatitis, Acute Necrotizing (2) · Psychological Well-Being (2)
Receptor Protein-Tyrosine Kinases (8) · LY6K protein, human (5) · Adjuvants, Pharmaceutic (2) · HLA-A*24:02 antigen (2) · montanide ISA 51 (2) · Continuity of Patient Care (1) · Decontamination (1) · Diclofenac (1) · Enteral Nutrition (1) · Hydrochlorothiazide (1) · KIF20B protein, human (1) · NUF2 protein, human (1) · Parenteral Nutrition (1) · RNF43 protein, human (1) · Telmisartan (1)
Japan (41) · Hong Kong (4) · China (3) · Indonesia (3) · Canada (1) · Czechia (1) · France (1) · India (1) · Malaysia (1) · Nepal (1) · Philippines (1) · Singapore (1) · South Korea (1) · Taiwan (1) · Thailand (1)
Naohide Yamashita, MD/PhD (6) · Yataro Daigo, MD, PhD (4) · Masaru Shinozaki, MD/PhD (3) · Yousuke Nakai (3) · Dianis Wulan Sari, Ph.D (2) · George Lau, MD (2) · Haruo Shintaku, MD, PhD (2) · Naohide Yamashita, MD, PhD (2) · Ahmed Ehsanur Rahman, MPH, MBBS (1) · Atsuo Yamada, MD (1) · Ayumi Yoshizaki, MD, PhD (1) · D M Emdadul Hoque, MPH, MBBS (1) · Hirotaka Chikuda, MD, PhD (1) · Hiroyuki Isayama, MD, PhD (1) · Jasmin Khan, MPH, MSS (1)
PMID 20104072, PMID 21893577, PMID 23924165, PMID 26447149, PMID 27933747, PMID 28982258, PMID 29615078, PMID 29724194, PMID 29735587, PMID 29780873, PMID 29879916, PMID 31563627, PMID 31574127, PMID 32236104, PMID 32779730, PMID 34607377, PMID 34751757, PMID 35136981, PMID 35663276, PMID 36175098, PMID 36372869, PMID 37226252, PMID 38279402, PMID 38294008, PMID 39130048, PMID 39182137, PMID 39293050, PMID 39818975, PMID 41720198, PMID 41851699, PMID 42013608, PMID 42831056