8 recruiting, 6 completed, 3 not yet recruiting, 2 active not recruiting. 13 Not applicable, 2 Phase 4, 1 Early Phase 1, 1 Phase 1, 1 Phase 2.
Follow Overweight and Obese Adults: new trials by email Literature Review of Overweight and Obese Adults trials Research Report on Overweight and Obese Adults
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Single and Multiple Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP6590 in Participants With Normal Weight, Overweight and Obesity ZP6590, solution for injection, Placebo, solution for injection - Healthy Participants Study, Overweight and Obese Adults | Early Phase 1 | Recruiting | Zealand Pharma | 88 | 2026-07-09 | 2026-08-13 |
| A 12-week Field Trial of the Movámonos Physical Activity Support Program Movámonos Physical Activity Support Program - Overweight and Obese Adults, Physical Inactivity | Not applicable | Not yet recruiting | University of Colorado, Denver | 20 | 2026-05-15 | 2026-05-01 |
| RWS of of Liraglutide Alone and in Combination With Orlistat for Weight Loss in Overweight/Obese Patients. liraglutide monotherapy, liraglutide combined with orlistat - Overweight and Obese Adults | Phase 4 | Not yet recruiting | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 120 | 2026-05-01 | 2026-03-23 |
| Effects of Obesity on Autophagy and mTORC1 Signalling in Skeletal Muscle Skeletal muscle biopsy, venous blood sampling, Protein-Rich Beverage - Overweight and Obese Adults | Recruiting | University of Birmingham | 24 | 2026-04-15 | 2026-08-19 | |
| Exercise Methods for Overweight and Obese Individuals High-Intensity Interval Training (HIIT) - Overweight and Obese Adults | Not applicable | Completed | Istanbul Medipol University Hospital | 40 | 2026-03-01 | 2026-11-04 |
| A Study of SYNT-101 to Test Safety, Tolerability and Pharmacodynamics of SYNT-101 in Healthy and Overweight Adults SYNT101, Placebo - Healthy, Overweight and Obese Adults | Phase 1 | Completed | Syntis Bio | 55 | 2026-01-13 | 2026-08-26 |
| Plant-Based Online Weight Loss Through Education and Resources Program and Study Low-fat, vegan diet - Type 2 Diabetes, Overweight and Obese Adults | Not applicable | Recruiting | Physicians Committee for Responsible Medicine | 100 | 2026-01-02 | 2026-09-17 |
| Behavioral Weight Loss and Sleep Health Intervention BWL+Sleep - Overweight and Obese Adults | Not applicable | Active not recruiting | University of Colorado, Denver | 25 | 2025-12-10 | 2026-09-03 |
| Eatit's Obesity Intervention: Effects on Weight, Eating Habits and Health Lifestyle Intervention for Obesity - Overweight and Obese Adults, Obese Patients (BMI ≥ 30 kg/m²) | Not applicable | Recruiting | Eatit AB | 93 | 2025-09-03 | 2025-09-19 |
| Sex Hormones as Regulators of the Age- and Sex-dependent Benefits of Caloric Restriction Phase 1 - Maintenance Diet, Phase 2 - Weight loss diet - Overweight and Obese Adults, Healthy | Not applicable | Recruiting | University of Aberdeen | 75 | 2025-07-09 | 2025-07-18 |
| CHRONO-NUTRITION APPLICATION: THE EFFECT OF FIBER JELLY ON POST PRANDIAL BLOOD GLUCOSE, SATIETY AND WEIGHT LOSS AMONG OVERWEIGHT WOMEN Fiber jelly - Overweight and Obese Adults | Not applicable | Completed | Surabaya State University | 28 | 2025-06-30 | 2026-01-28 |
| Effect of Vegetables on Weight Status of University Population Non-starchy vegetables will be provided to the participants as an intervention. - Obesity Control, Overweight and Obese Adults | Not applicable | Not yet recruiting | University of Veterinary and Animal Sciences, Lahore - Pakistan | 40 | 2025-02-17 | 2025-01-07 |
| Acute Effects of Isoenergetic HIIE vs. MICE on Key Parameters of Fat Mass Loss in Young Females With Overweight or Obesity Exercise - Overweight and Obese Adults, High Intensity Interval Exercise (HIIE) | Not applicable | Recruiting | Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques | 15 | 2025-02-01 | 2026-08-31 |
| Effects of D-Chiro-Inositol Combined with Metformin on Insulin Resistance in People with Overweight or Obesity and T2DM D-Chiro-Inositol Combined with Metformin, Placebo in combination with metformin - Type 2 Diabetes, Overweight and Obese Adults | Phase 4 | Active not recruiting | Campus Bio-Medico University | 16 | 2025-01-10 | 2025-03-11 |
| Screening for Malnutrition in Obese Patients Overweight and Obese Adults, Malnutrition or Risk of Malnutrition | Recruiting | HAN University of Applied Sciences | 2000 | 2024-10-02 | 2024-11-08 | |
| Study of the Efficacy and Safety of Nicotinamide in Patients With Liver Fibrosis (NICOFIB) Nicotinamide, Placebo - Fatty Liver, Obesity | Phase 2 | Recruiting | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 30 | 2024-04-23 | 2025-11-18 |
| Psychophysiological and Cognitive Responses to Low-Volume High-Intensity Interval Exercise in Overweight-to-Obese Adults Low-Volume High-Intensity Interval Exercise (Lv-HIIE) - Overweight and/or Obesity, Overweight and Obese Adults | Not applicable | Completed | Universiti Sains Malaysia | 32 | 2023-03-01 | 2025-12-11 |
| Role of Leucine on Muscle Preservation During Weight Loss in Older Men Placebo, Protein, Leucine - Overweight and Obese Adults, BMI>=23 kg/m2 | Not applicable | Completed | Nanyang Technological University | 80 | 2022-11-14 | 2026-08-24 |
| Association Analysis of Aerobic Capacity and Expiratory Forced Vital Capacity in Overweight and Obese Adults After Submaximal Exercise Training of Three Weeks submaximal exercise testing according to ACSM guidelines - Overweight and Obese Adults | Not applicable | Unknown | Foundation University Islamabad | 30 | 2020-09-30 | 2021-12-06 |
| Dose Response of Leucine on Muscle Maintenance During Weight Loss leucine - Overweight and Obese Adults, BMI >= 23 | Not applicable | Completed | Nanyang Technological University | 92 | 2020-08-18 | 2026-08-18 |
Overweight (20) · Obesity (12) · Diabetes Mellitus, Type 2 (2) · Intermittent Fasting (2) · Weight Loss (2) · Fatty Liver (1) · Insulin Resistance (1) · Liver Cirrhosis (1) · Malnutrition (1) · Motor Activity (1) · Non-alcoholic Fatty Liver Disease (1) · Sedentary Behavior (1)
Body Weight (20) · Nutrition Disorders (20) · Nutritional and Metabolic Diseases (20) · Overnutrition (20) · Pathological Conditions, Signs and Symptoms (20) · Signs and Symptoms (20) · Behavior (4) · Body Weight Changes (2) · Diabetes Mellitus (2) · Endocrine System Diseases (2) · Fasting (2) · Feeding Behavior (2) · Glucose Metabolism Disorders (2) · Metabolic Diseases (2) · Digestive System Diseases (1)
Leucine (2) · Absorptiometry, Photon (1) · Adiposity (1) · Blood Specimen Collection (1) · Diet, Fat-Restricted (1) · Diet, Vegan (1) · Exercise (1) · High-Intensity Interval Training (1) · Injections (1) · Metformin (1) · Methods (1) · Niacinamide (1) · Orlistat (1) · Proteins (1) · Solutions (1)
Nanyang Technological University (2) · University of Colorado, Denver (2) · Campus Bio-Medico University (1) · Eatit AB (1) · Foundation University Islamabad (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1) · HAN University of Applied Sciences (1) · Istanbul Medipol University Hospital (1) · Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques (1) · Physicians Committee for Responsible Medicine (1) · Surabaya State University (1) · Syntis Bio (1) · The Fourth Affiliated Hospital of Zhejiang University School of Medicine (1) · Universiti Sains Malaysia (1) · University of Aberdeen (1)
Pakistan (2) · Singapore (2) · United Kingdom (2) · United States (2) · Australia (1) · Brazil (1) · Germany (1) · Indonesia (1) · Italy (1) · Malaysia (1) · Netherlands (1) · Spain (1) · Sweden (1) · Turkey (Türkiye) (1)
Alexandra M Johnstone, Professor (1) · Dr Sanna Pervaiz, MSPT (1) · Dr Summyia Siddique Malik, MSPT (1) · Nathan Hodson (1) · Qaisar Raza, PhD (1) · Victoria Catenacci, MD (1)
2023 (1), 2025 (1), K24HL169755 (1)