10 completed, 6 active not recruiting, 3 not yet recruiting, 2 unknown. 21 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Completed 10, Active not recruiting 6, Not yet recruiting 3, Unknown 2 |
Follow Overdose: new trials by email Literature Review of Overdose trials Research Report on Overdose
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Permanent Supportive Housing Overdose Prevention+ Study TA Intervention - Overdose, Substance Use | Not applicable | Not yet recruiting | NYU Langone Health | 2940 | 2027-07-01 | 2026-05-06 |
| The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study Community Paramedic Standard of Care (CP SOC), CROSSROADS - Opioid Use Disorder, Overdose, Drug | Not applicable | Not yet recruiting | Duke University | 400 | 2027-02-01 | 2026-10-14 |
| A Universal Primary Care Based Intervention to Reduce Youth Overdose Risk Aim 3 Brief youth overdose prevention education, Usual Standard of Care - Overdose | Not applicable | Not yet recruiting | Boston Medical Center | 648 | 2026-11-01 | 2026-10-01 |
| A Universal Primary Care Based Intervention to Reduce Youth Overdose Risk Brief youth overdose prevention education, Information about Naloxone, Usual standard of care - Overdose | Not applicable | Active not recruiting | Boston Medical Center | 22 | 2025-08-25 | 2026-08-07 |
| Motivational Interviewing to Increase Uptake of Drug Checking and Safe Drug Use Behaviors to Reduce Overdose MI-CHANCE (TS + FTIR + MI), TS + FTIR + Flu and Hepatitis A Education - Overdose | Not applicable | Active not recruiting | University of California, San Diego | 588 | 2025-03-03 | 2026-04-06 |
| Home Safety Intervention household safety intervention - Suicide, Firearm Injury | Not applicable | Completed | VA Office of Research and Development | 40 | 2024-10-08 | 2026-08-28 |
| The Ganchero Intervention for Migrant People Who Inject Drugs From Puerto Rico in New York City Ganchero intervention - HIV Infections, HCV | Not applicable | Active not recruiting | North Jersey AIDS Alliance dba North Jersey Community Research Initiative (NJCRI) | 69 | 2024-05-01 | 2026-07-24 |
| Permanent Supportive Housing Overdose Prevention CSH-Delivered Overdose Prevention Support - Overdose | Not applicable | Active not recruiting | NYU Langone Health | 1350 | 2023-09-26 | 2026-05-05 |
| Improving Access to Naloxone to Prevent Opioid Overdose Deaths (SAIA-Naloxone) Naloxone, Usual intervention - Overdose, Implementation as Usual | Not applicable | Active not recruiting | RTI International | 31 | 2023-07-01 | 2026-10-20 |
| Pharmacist-Led Interventions to Increase Access to Medications for Opioid Use Disorders (PLI-MOUD) Pharmacist Narcan Training, BIRT, SMC - Opioid Use Disorder, Overdose | Not applicable | Completed | University of Arkansas | 267 | 2023-05-05 | 2026-04-06 |
| Smartphone Intervention for Overdose and COVID-19 iThrive WI Intervention - Substance Use Disorders, Overdose | Not applicable | Completed | University of Wisconsin, Madison | 60 | 2022-12-19 | 2024-12-05 |
| Community-based Education, Navigation, and Support Intervention for Military Veterans Overdose Education and Naloxone Distribution, Advanced Education in Safer Substance Use, Treatment, and Self-Care, Social Service and Health Navigation - Overdose, Opioid Use Disorder | Not applicable | Active not recruiting | New York University | 300 | 2022-10-21 | 2026-06-03 |
| Evaluation of a Medication Health Center to Promote Opioid Safety MHC Outreach Intervention - Overdose | Not applicable | Unknown | Kaiser Permanente | 14 | 2022-06-15 | 2024-06-14 |
| An Evaluation of a Social Network Intervention for Primary and Secondary Prevention of Opioid Overdoses Peer Education, Narcan Nasal Product - Overdose | Not applicable | Completed | Johns Hopkins Bloomberg School of Public Health | 614 | 2019-03-15 | 2024-01-24 |
| SOONER Feasibility Study Protocol SOONER Training and Naloxone Kit Kit, Community or Hospital-Based Training - Overdose | Not applicable | Completed | Unity Health Toronto | 90 | 2019-01-23 | 2022-05-23 |
| Project POINT: Effectiveness and Scalability of an Overdose Survivor Intervention POINT - Substance Use Disorders, Overdose | Not applicable | Completed | Indiana University | 249 | 2018-02-12 | 2023-10-06 |
| The Impact of a Web-Based Naloxone Intervention Under Standing Orders to Patients Prescribed Chronic Opioid Therapy Naloxone Navigator (NN) - Overdose, Risk Behavior | Not applicable | Unknown | Kaiser Permanente | 1004 | 2017-12-21 | 2024-05-20 |
| The Impact of Co-Dispensing Naloxone to Patients Prescribed Chronic Opioid Therapy Co-Dispensing - Overdose, Risk Behavior | Not applicable | Completed | Kaiser Permanente | 7 | 2017-11-27 | 2023-03-03 |
| AWAITS: A Web-based E-health Application for Active Illicit Opioid Users self-administered, e-health application - Opioid-use Disorder, IV Drug Usage | Not applicable | Completed | University of Cincinnati | 24 | 2017-11-08 | 2019-04-10 |
| Impact of Direct Outreach to Expand Access to Naloxone in the Context of Standing Orders Naloxone Navigator 1.0 - Opioid Abuse, Overdose | Not applicable | Completed | Kaiser Permanente | 325 | 2017-08-14 | 2023-08-24 |
Showing 20 of 21. Sign in to see all of them.
Drug Overdose (21) · Opioid-Related Disorders (7) · Substance-Related Disorders (6) · Risk-Taking (3) · HIV Infections (2) · COVID-19 (1) · Harm Reduction (1) · Suicide (1)
Chemically-Induced Disorders (21) · Drug Misuse (21) · Mental Disorders (21) · Prescription Drug Misuse (21) · Substance-Related Disorders (15) · Narcotic-Related Disorders (7) · Behavior (5) · Infections (3) · RNA Virus Infections (3) · Virus Diseases (3) · Blood-Borne Infections (2) · Communicable Diseases (2) · Genital Diseases (2) · Immune System Diseases (2) · Immunologic Deficiency Syndromes (2)
Naloxone (2) · Educational Status (1) · Influenza Vaccines (1) · Motivational Interviewing (1) · Palliative Care (1) · Residence Characteristics (1) · Self Care (1) · Social Work (1) · Spectroscopy, Fourier Transform Infrared (1) · Therapeutics (1)
Kaiser Permanente (4) · Boston Medical Center (2) · NYU Langone Health (2) · University of Cincinnati (2) · Duke University (1) · Indiana University (1) · Johns Hopkins Bloomberg School of Public Health (1) · New York University (1) · North Jersey AIDS Alliance dba North Jersey Community Research Initiative (NJCRI) (1) · RTI International (1) · Unity Health Toronto (1) · University of Arkansas (1) · University of California, San Diego (1) · University of Wisconsin, Madison (1) · VA Office of Research and Development (1)
United States (20) · Canada (1)
Ingrid Binswanger, MD (3) · Jason Glanz, PhD (3) · Amy Yule, MD (2) · Theresa Winhusen, PhD (2) · Alexander S Bennett, PhD (1) · Carl A. Latkin, PhD (1) · Dennis P Watson, PhD (1) · Joseph A Simonetti, MD MPH (1) · Kelly Doran, MD (1) · Kelly Doran, MD, MHS (1) · Lauren Brinkley-Rubinstein, PhD (1) · Meghan N Breckling, PharmD (1) · Rachel E Gicquelais, PhD, MPH (1) · Sarah Bagley, MD (1) · Sarah Bagley, MD MSc (1)
PMID 27004905, PMID 31722937, PMID 34223388, PMID 35132556, PMID 37287026, PMID 38258819, PMID 39421268, PMID 40560908, PMID 40737120, PMID 41029610, PMID 41316389
R01DA042059 (3), R61DA062217 (2), 1IK2HX002861-01A2 (1), R33DA045850 (1), RM1DA064518 (1), UG3DA044826-01 (1), UG3DA063084 (1)