15 completed, 6 recruiting, 6 terminated, 4 unknown. 14 Phase 2, 8 Not applicable, 5 Phase 1, 5 Phase 3, 1 Phase 4.
Follow Osteosclerosis: new trials by email Literature Review of Osteosclerosis trials Research Report on Osteosclerosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Gene-Modified Stem Cell Therapy for Children With Autosomal Recessive Osteopetrosis (ARO) FT024 - Osteopetrosis | Phase 1 / Phase 2 | Recruiting | Fondazione Telethon | 8 | 2026-06-20 | 2026-06-24 |
| Physiotherapy and Rehabilitation in Melorheostosis: A Case Report Assigned Interventions - Melorheostosis | Not applicable | Active not recruiting | Yeditepe University | 1 | 2026-04-18 | 2026-06-26 |
| Radiographic Assessment of Bone Dimension Around Immediate Implants With FDBA and I-PRF vs FDBA Alone i-PRF and FDBA - Bone Density Increased | Phase 2 | Unknown | Krishnadevaraya College of Dental Sciences & Hospital | 20 | 2023-07-15 | 2024-07-30 |
| Outcomes of Patients With Osteopetrosis Weight-bearing Bone Fractures Open reduction and internal fixation - Osteopetrosis | Not applicable | Completed | Kasr El Aini Hospital | 6 | 2022-01-01 | 2024-07-26 |
| Milk Supplementation and Bone Health in Children Formula milk, Regular milk, Control foods - Bone Density Increased, Body Height | Not applicable | Unknown | Sun Yat-sen University | 254 | 2021-09-03 | 2021-10-12 |
| Effect of Low-level Laser Therapy on Type II Controlled Diabetic Patients After Dental Implant Insertion low-level laser therapy (LLLT) - T2DM (Type 2 Diabetes Mellitus), Low-level Laser Therapy | Not applicable | Completed | Sinai University | 40 | 2021-03-03 | 2022-03-15 |
| Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC data collection - Primary Immunodeficiency (PID), Congenital Bone Marrow Failure Syndromes | Recruiting | Paul Szabolcs | 50 | 2020-08-20 | 2026-01-13 | |
| Relationship Between Circulating Sclerostin and Bone Lesions in Patients With Mastocytosis SCLEROSTIN - Mastocytosis, Bones | Recruiting | Medical University of Lublin | 50 | 2019-09-01 | 2024-06-03 | |
| Effects of Exercises on Total Body Health in Children With Acute Lymphoblastic Leukemia Exercise therapy - Acute Lymphoblastic Leukemia, Bone Density Increased | Not applicable | Completed | Bezmialem Vakif University | 20 | 2019-08-01 | 2020-01-18 |
| Effects of Soy Isoflavone on Bone Health Among Saudi Female Students Imam Abdulrahman Bin Faisal University. Soy Isoflavone supplement - Soy Isoflavone Effect, Bone Density, Low | Phase 3 | Completed | Imam Abdulrahman Bin Faisal University | 28 | 2018-12-12 | 2023-09-28 |
| Bone Density in Immediate Implant Placment and Loading(BDIIPL) Prf - Bone Density Increased | Not applicable | Unknown | Ahmed adel shaaban | 10 | 2018-09-01 | 2018-08-22 |
| Minimally Invasive Ridge Augmentation Low Level Laser Therapy - Alveolar Bone Loss, Bone Density Increased | Not applicable | Completed | Krishnadevaraya College of Dental Sciences & Hospital | 20 | 2017-11-10 | 2019-12-18 |
| Emdogain Implementation With Transcrestal Sinus Lifting and Dental Implant Placement Enamel Matrix Protein - Osseointegration Failure of Dental Implant, Bone Density Increased | Phase 4 | Completed | T.C. Dumlupınar Üniversitesi | 24 | 2017-01-01 | 2022-08-18 |
| ACTIMMUNE in Intermediate Osteopetrosis Interferon gamma-1b - Osteopetrosis | Phase 2 | Completed | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 5 | 2016-02-22 | 2024-10-22 |
| Use of ACTIMMUNE in Patients With ADO2 ACTIMMUNE - Autosomal Dominant Osteopetrosis Type 2 | Phase 2 | Completed | Indiana University | 12 | 2016-01-01 | 2021-01-08 |
| Natural History, Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic Disease Rheumatic Disease | Recruiting | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 350 | 2015-08-16 | 2026-10-02 | |
| MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis Stem Cell Transplantation, IMD Preparative Regimen, Osteopetrosis Only Preparative Regimen - Mucopolysaccharidosis Disorders, Hurler Syndrome | Phase 2 | Active not recruiting | Masonic Cancer Center, University of Minnesota | 149 | 2014-07-10 | 2026-01-07 |
| Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant BPX-501 T cells, Rimiducid - Acute Lymphoblastic Leukemia, Leukemia, Acute Myeloid (AML), Child | Phase 1 / Phase 2 | Active not recruiting | Bellicum Pharmaceuticals | 120 | 2014-04-01 | 2022-07-12 |
| Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant BPX-501 T cells, Rimiducid - Acute Lymphoblastic Leukemia, Leukemia, Acute Myeloid (AML), Child | Phase 1 / Phase 2 | Terminated | Bellicum Pharmaceuticals | 187 | 2014-04-01 | 2023-09-29 |
| Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT Hydroxyurea, Alemtuzumab, Fludarabine - Primary Immunodeficiency (PID), Congenital Bone Marrow Failure Syndromes | Phase 2 | Recruiting | Paul Szabolcs | 100 | 2014-02-04 | 2025-12-15 |
Showing 20 of 35. Sign in to see all of them.
Osteopetrosis (22) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (5) · Anemia, Sickle Cell (4) · Leukemia, Myeloid, Acute (4) · Leukodystrophy, Globoid Cell (4) · Mucopolysaccharidosis I (4) · Myelodysplastic Syndromes (4) · Primary Immunodeficiency Diseases (4) · alpha-Mannosidosis (4) · Anemia, Diamond-Blackfan (3) · Bone Marrow Failure Disorders (3) · Chediak-Higashi Syndrome (3) · Congenital amegakaryocytic thrombocytopenia (3) · Cytopenia (3)
Bone Diseases (34) · Bone Diseases, Developmental (34) · Musculoskeletal Diseases (34) · Osteochondrodysplasias (34) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (12) · Hemic and Lymphatic Diseases (10) · Metabolic Diseases (10) · Nutritional and Metabolic Diseases (10) · Genetic Diseases, Inborn (9) · Immune System Diseases (9) · Hematologic Diseases (8) · Lymphatic Diseases (8) · Skin and Connective Tissue Diseases (8) · Connective Tissue Diseases (7)
Alemtuzumab (4) · Busulfan (4) · Cyclophosphamide (3) · Stem Cell Transplantation (3) · fludarabine (3) · fludarabine phosphate (3) · AP 1903 reagent (2) · Bone Marrow Transplantation (2) · Cord Blood Stem Cell Transplantation (2) · Low-Level Light Therapy (2) · interferon gamma-1b (2) · thymoglobulin (2) · Antibodies (1) · Antilymphocyte Serum (1) · Bone Transplantation (1)
Masonic Cancer Center, University of Minnesota (3) · Bellicum Pharmaceuticals (2) · Krishnadevaraya College of Dental Sciences & Hospital (2) · Paul Szabolcs (2) · University of Chicago (2) · Ahmed adel shaaban (1) · Bezmialem Vakif University (1) · Children's Hospital Los Angeles (1) · Christopher Dvorak (1) · Columbia University (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · FDA Office of Orphan Products Development (1) · Fondazione Telethon (1) · Imam Abdulrahman Bin Faisal University (1) · Indiana University (1)
United States (19) · Turkey (Türkiye) (3) · Egypt (2) · India (2) · Italy (2) · China (1) · Denmark (1) · Iran (1) · Poland (1) · Saudi Arabia (1) · United Kingdom (1)
Paul Orchard, MD (2) · Paul Szabolcs, MD (2) · Amir Ali Hamidieh, MD (1) · Andrew Gilman, MD (1) · Aneta A Szudy-Szczyrek, MD., PhD. (1) · Christopher Dvorak, MD (1) · Dale M Kobrin, M.D. (1) · Deniz Ozbay, DDS PhD (1) · Hisham Abdel-Azim, MD (1) · James Garvin, MD, PhD (1) · Joshua J Zimmerberg, M.D. (1) · Kim Brixen, Professor (1)
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