3 completed, 3 not yet recruiting, 3 recruiting, 2 unknown. 5 Phase 4, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 5 | Recruiting 2, Completed 1, Not yet recruiting 1, Terminated 1 |
| Not applicable | 1 | Unknown 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow Open Fracture: new trials by email Literature Review of Open Fracture trials Research Report on Open Fracture
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SurgWeek-2: Identifying the Global Burden of Post Operative Complications: an International Prospective Cohort Study Protocol Surgery Complications, Surgery | Not yet recruiting | University of Birmingham | 100000 | 2026-08-31 | 2026-08-25 | |
| Implementation of Vancomycin Powder Application in the Emergency Department for Open Fractures Vancomycin (VAN) treatment, Standard Open Fracture Care - Open Fracture | Phase 3 | Not yet recruiting | Atlantic Health System | 100 | 2026-06-10 | 2026-06-22 |
| Volume Reduction for Open Fracture Irrigation 0.9% Sodium Chloride - Open Fracture | Phase 4 | Recruiting | Inova Health Care Services | 200 | 2026-03-02 | 2026-04-13 |
| Powdered Intrawound Vancomycin in Open Fractures Trial Vancomycin 1000 MG - Open Fracture, Trauma | Phase 4 | Not yet recruiting | University of Manitoba | 350 | 2024-11-01 | 2024-09-19 |
| Evaluation of STIMULAN Device and AI Model in Preventing Fracture Infections STIMULAN - Open Fracture | Not applicable | Unknown | Università Vita-Salute San Raffaele | 40 | 2023-11-01 | 2024-04-25 |
| OCT in Open Fracture and Infected Fracture Open Fracture, Infected Fracture - Trauma Injury, Trauma | Recruiting | Dartmouth-Hitchcock Medical Center | 40 | 2023-03-27 | 2026-10-02 | |
| Placement of Antibiotic Powder in Wounds During the Emergency Room Vancomycin - Open Fracture | Phase 4 | Recruiting | The University of Texas Health Science Center at San Antonio | 200 | 2020-10-05 | 2026-09-30 |
| Septic Management and Outcome of Open Fracture management and follow up of all open fractures - Open Fracture, Pseudarthrosis | Completed | Hospices Civils de Lyon | 400 | 2020-05-15 | 2022-01-12 | |
| Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens Ceftriaxone, Ampicillin/sulbactam, Piperacillin/tazobactam - Open Fracture, Post-Op Wound Infection | Phase 4 | Terminated | Mercy Health Ohio | 17 | 2018-07-09 | 2020-09-11 |
| Preventing Infections in Orthopaedic Patients Open Fracture | Unknown | Olayemi Osiyemi MD | 50 | 2016-11-01 | 2016-10-28 | |
| Assessment of Severe Extremity Wound Bioburden at the Time of Definitive Wound Closure or Coverage Open Fracture | Completed | Major Extremity Trauma Research Consortium | 646 | 2011-09-01 | 2026-05-05 | |
| Efficacy of DBM on Fractures of the Shinbone (Tibia) Grafton DBM, Reamings - Closed Fracture, Open Fracture | Phase 4 | Completed | Emory University | 16 | 2006-03-01 | 2013-09-24 |
Fractures, Open (12) · Infections (3) · Fractures, Bone (2) · Surgical Wound Infection (2) · Wound Infection (2) · Wounds and Injuries (2) · Accidental Injuries (1) · Fractures, Closed (1) · Pseudarthrosis (1)
Fractures, Bone (10) · Wounds and Injuries (10) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Postoperative Complications (2) · Fractures, Ununited (1) · Infections (1)
Therapeutics (3) · Vancomycin (3) · Cefazolin (1) · Ceftriaxone (1) · Clindamycin (1) · Gentamicins (1) · Open Fracture Reduction (1) · Piperacillin, Tazobactam Drug Combination (1) · Saline Solution (1) · Sodium Chloride (1) · sultamicillin (1)
Atlantic Health System (1) · Dartmouth-Hitchcock Medical Center (1) · Emory University (1) · Hospices Civils de Lyon (1) · Inova Health Care Services (1) · Major Extremity Trauma Research Consortium (1) · Mercy Health Ohio (1) · Olayemi Osiyemi MD (1) · The University of Texas Health Science Center at San Antonio (1) · University of Birmingham (1) · University of Manitoba (1) · Università Vita-Salute San Raffaele (1)
United States (8) · Canada (1) · France (1) · Italy (1)
Abraham Goch, MD (1) · Allison R Lauver, PharmD (1) · Chad W Donley, MD (1) · David J Gemmel, PhD (1) · Gabriel Larose, MD, MSc, FRCSC (1) · Ida L Gitajn (1) · Madison Price, MD (1) · Michael J Bosse, MD (1) · Natalie I Rine, PharmD (1) · Olayemi Osiyemi, MD (1) · Paul T Miller, PharmD (1) · Robert A De Lorenzo, MD (1) · Stuart Drew, DO (1) · Thomas J Moore, MD (1) · Tyson T Schrickel, MD (1)