11 terminated. 11 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 11 | Terminated 11 |
| Phase 1 | 1 | Terminated 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Obsessive-Compulsive Disorder: new trials by email Literature Review of Obsessive-Compulsive Disorder trials Research Report on Obsessive-Compulsive Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Randomized Controlled Trial of Intranasal Ketamine vs. Intranasal Midazolam in Individuals With OCD Intranasal Ketamine, Intranasal Midazolam - Obsessive-Compulsive Disorder | Phase 2 | Terminated | New York State Psychiatric Institute | 2 | 2014-09-01 | 2017-05-03 |
| A Trial of Intranasal Ketamine for the Treatment of Obsessive-Compulsive Disorder Ketamine, Placebo - Obsessive-Compulsive Disorder | Phase 2 | Terminated | Mclean Hospital | 1 | 2014-09-01 | 2017-05-12 |
| Study to Evaluate the Effect of AFQ056 in Obsessive Compulsive Disorder (OCD) Patients Resistant to Selective Serotonin Reuptake Inhibitor (SSRI) Therapy AFQ056, Placebo - Patient Diagnosed With OCD and Resistant to SSRI Treatment, Failed SSRI Over 12 Weeks at Appropriate Doses | Phase 2 | Terminated | Novartis Pharmaceuticals | 50 | 2013-11-01 | 2017-01-02 |
| Intravenous Ketamine in the Treatment of Obsessive-Compulsive Disorder Ketamine, Midazolam - Obsessive Compulsive Disorder | Phase 1 / Phase 2 | Terminated | Wayne Goodman MD | 3 | 2012-06-01 | 2018-01-18 |
| Efficacy and Safety Study of Low-Dose Ondansetron For Adjunctive Therapy In Adult Patients With Obsessive-Compulsive Disorder Ondansetron, Placebo - Obsessive-compulsive Disorder | Phase 2 | Terminated | Transcept Pharmaceuticals | 130 | 2011-01-01 | 2013-01-18 |
| A Randomized, Double-Blind, Placebo-Controlled Trial of Flumazenil for the Treatment of Obsessive Compulsive Disorder Flumazenil - Obsessive Compulsive Disorder | Phase 2 | Terminated | Parkway Medical Center | 11 | 2009-10-01 | 2014-04-22 |
| Naltrexone SR and Fluoxetine Combination Therapy in Subjects With Obsessive-Compulsive Disorder Fluoxetine 60 mg, Naltrexone 32 mg and fluoxetine 60 mg, Naltrexone SR 32 mg - Obsessive-Compulsive Disorder | Phase 2 | Terminated | Orexigen Therapeutics, Inc | 8 | 2008-09-01 | 2012-11-29 |
| Study of NPL-2003 in Adolescents With Obsessive Compulsive Disorder (OCD) Minocycline - Obsessive Compulsive Disorder | Phase 2 | Terminated | Neuropharm | 6 | 2007-07-01 | 2012-04-27 |
| N-Acetylcysteine Augmentation in Treatment-Refractory Obsessive-Compulsive Disorder N-Acetylcysteine, placebo - Obsessive-Compulsive Disorder | Phase 2 | Terminated | Yale University | 10 | 2006-06-01 | 2020-04-02 |
| Augmentation Study of Levetiracetam in Obsessive Compulsive Disorder Sertraline, Levetiracetam, Placebo - Obsessive-Compulsive Disorder | Phase 2 / Phase 3 | Terminated | Duke University | 12 | 2005-11-01 | 2013-04-11 |
| Radiosurgical Treatment for Obsessive-compulsive Disorder ventral capsular/ventral striatal gamma capsulotomy - Obsessive-compulsive Disorder | Phase 2 | Terminated | University of Sao Paulo General Hospital | 16 | 2003-07-01 | 2012-10-12 |
Anxiety Disorders (1) · Compulsive Behavior (1) · Obsessive Behavior (1)
Mental Disorders (11) · Anxiety Disorders (10) · Behavior (1) · Behavioral Symptoms (1) · Impulsive Behavior (1)
Ketamine (3) · Acetylcysteine (1) · Flumazenil (1) · Fluoxetine (1) · Levetiracetam (1) · Midazolam (1) · Minocycline (1) · Naltrexone (1) · Ondansetron (1) · Radiosurgery (1) · Sertraline (1) · mavoglurant (1)
Duke University (1) · Mclean Hospital (1) · Neuropharm (1) · New York State Psychiatric Institute (1) · Novartis Pharmaceuticals (1) · Orexigen Therapeutics, Inc (1) · Parkway Medical Center (1) · Transcept Pharmaceuticals (1) · University of Sao Paulo General Hospital (1) · Wayne Goodman MD (1) · Yale University (1)
United States (9) · Brazil (1) · Bulgaria (1) · Czechia (1) · Germany (1) · Mexico (1) · Switzerland (1)
Al Rivera, MD (1) · Andrew W Goddard, MD (1) · Antonio C Lopes, MD, PhD (1) · Brian P Brennan, M.D. (1) · Carolyn I Rodriguez, M.D., Ph.D. (1) · Christopher J Pittenger, MD, Ph.D. (1) · Eric Hollander, MD (1) · James G Sullivan, MD (1) · Jeffrey S Simon, MD (1) · Jeffrey T Apter, MD, PA (1) · Kyle Lapidus, MD (1) · Mohammad Bari, MD (1) · Naresh P Emmanuel, MD (1) · Robert Riesenberg, MD (1)