4 completed, 1 terminated. 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 4, Terminated 1 |
Follow Nicotine Addiction: new trials by email Literature Review of Nicotine Addiction trials Research Report on Nicotine Addiction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Semaglutide on Nicotine Intake Semaglutide, Sham/placebo - Tobacco Use Disorder, Nicotine Addiction | Phase 2 | Completed | University of North Carolina, Chapel Hill | 24 | 2022-10-07 | 2025-08-22 |
| Quit Smoking Study for People Who Use E-Cigarettes Nicotine replacement therapy patch, Nicotine replacement therapy lozenge, Quit electronic cigarettes - Nicotine Addiction, E-Cig Use | Phase 2 | Completed | University of Vermont | 396 | 2021-06-27 | 2025-05-22 |
| Abuse Liability of Reduced Nicotine Content Cigarettes in the Context of Concurrent E-Cigarette Use Smoking research cigarettes with e-cigarette, Nicotine discrimination thresholds - Nicotine Addiction, Cigarette Smoking | Phase 2 | Completed | Rose Research Center, LLC | 150 | 2019-05-01 | 2022-01-14 |
| Effects of ABT-089 on Smoking Abstinence Symptoms and Reward ABT-089, Placebo - Nicotine Addiction | Phase 2 | Terminated | University of Pennsylvania | 17 | 2013-03-01 | 2014-10-29 |
| Effect of Galantamine on Smoking Abstinence Galantamine ER - Nicotine Addiction | Phase 2 | Completed | University of Pennsylvania | 13 | 2012-02-01 | 2017-12-26 |
Tobacco Use Disorder (5) · Smoking (2) · Cigarette Smoking (1) · Smoking Cessation (1) · Vaping (1)
Chemically-Induced Disorders (5) · Mental Disorders (5) · Substance-Related Disorders (5) · Behavior (4) · Smoking (2) · Health Behavior (1) · Tobacco Smoking (1) · Tobacco Use (1)
Electronic Nicotine Delivery Systems (1) · Galantamine (1) · pozanicline (1) · semaglutide (1)
University of Pennsylvania (2) · Rose Research Center, LLC (1) · University of North Carolina, Chapel Hill (1) · University of Vermont (1)
United States (5)
Caryn Lerman, PhD (1) · Christian Hendershot, PhD (1) · Jed E Rose, Ph.D. (1) · Rebecca Ashare, Ph.D. (1)
R01DA042541 (1), R21DA047663 (1)