7 suspended. 7 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Suspended 7 |
| Phase 1 | 4 | Suspended 4 |
Follow Nervous System Neoplasms: new trials by email Literature Review of Nervous System Neoplasms trials Research Report on Nervous System Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CA-4948 in Combination With Pembrolizumab and Stereotactic Radiosurgery to Improve Treatment of Melanoma Brain Metastases Emavusertib, Pembrolizumab, Stereotactic Radiosurgery - Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma | Phase 1 / Phase 2 | Suspended | Mayo Clinic | 23 | 2026-11-30 | 2026-10-20 |
| PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma PEP-CMV vaccine, Tetanus booster, Nivolumab - Diffuse Midline Glioma, Diffuse Midline High-grade Glioma | Phase 1 / Phase 2 | Suspended | Washington University School of Medicine | 68 | 2026-11-30 | 2026-10-30 |
| Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM) NaviFUS System, Lumason, Bevacizumab - Glioblastoma Multiforme, Glioblastoma | Phase 1 / Phase 2 | Suspended | NaviFUS Corporation | 10 | 2024-10-22 | 2026-09-09 |
| Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases Azeliragon, Stereotactic radiosurgery, Corticosteroid - Cancer, Metastasis | Phase 1 / Phase 2 | Suspended | Baptist Health South Florida | 46 | 2023-11-17 | 2026-06-16 |
| A Phase 2 Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients with DIPG SONALA-001 (ALA) and MR-Guided Focused Ultrasound device (MRgFUS) - Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma | Phase 2 | Suspended | SonALAsense, Inc. | 15 | 2022-08-12 | 2024-09-19 |
| A Study of Atengenal and Astugenal in Diffuse, Intrinsic Pontine Glioma (DIPG) Antineoplaston therapy (Atengenal + Astugenal) - Diffuse, Intrinsic Pontine Glioma | Phase 2 | Suspended | Burzynski Research Institute | 1 | 2016-04-13 | 2025-09-16 |
| Biological Therapy in Treating Patients With Primary or Advanced Glioma aldesleukin, lymphokine-activated killer cells - Brain and Central Nervous System Tumors | Phase 2 | Suspended | Weill Medical College of Cornell University | 1997-07-01 | 2009-02-09 |
Brain Neoplasms (4) · Diffuse Intrinsic Pontine Glioma (3) · Glioblastoma (2) · Glioma (2) · Neoplasms (2) · Astrocytoma (1) · Central Nervous System Neoplasms (1) · Ependymoma (1) · Gliosarcoma (1) · Medulloblastoma (1) · Melanoma (1) · Neoplasm Metastasis (1) · Neoplasms, Nerve Tissue (1) · Recurrence (1)
Brain Diseases (7) · Central Nervous System Diseases (7) · Neoplasms by Site (7) · Nervous System Diseases (7) · Central Nervous System Neoplasms (6) · Neoplasms by Histologic Type (6) · Neoplasms, Germ Cell and Embryonal (6) · Neuroectodermal Tumors (6) · Neoplasms (5) · Neoplasms, Glandular and Epithelial (5) · Neoplasms, Nerve Tissue (5) · Neoplasms, Neuroepithelial (5) · Brain Neoplasms (3) · Brain Stem Neoplasms (3)
Radiosurgery (2) · Adrenal Cortex Hormones (1) · Bevacizumab (1) · Biopsy (1) · CA-4948 (1) · Dexamethasone (1) · Immunoglobulin G (1) · Magnetic Resonance Spectroscopy (1) · Methylprednisolone (1) · Nivolumab (1) · Specimen Handling (1) · Temozolomide (1) · aldesleukin (1) · antineoplaston A10 (1) · antineoplaston AS 2-1 (1)
Baptist Health South Florida (1) · Burzynski Research Institute (1) · Mayo Clinic (1) · NaviFUS Corporation (1) · SonALAsense, Inc. (1) · Washington University School of Medicine (1) · Weill Medical College of Cornell University (1)
United States (7)
Bently Doonan, MD, MS (1) · Corina Andresen, MD (1) · Eric M Thompson, M.D. (1) · Minesh Mehta, M.D. (1) · Roberta L. Hayes, PhD (1) · Stanislaw R. Burzynski, MD, PhD (1)
R01CA296813 (1), R44CA261516 (1)