39 unknown. 39 Phase 1, 15 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 39 | Unknown 39 |
| Phase 2 | 15 | Unknown 15 |
Follow Nervous System Neoplasms: new trials by email Literature Review of Nervous System Neoplasms trials Research Report on Nervous System Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluate the Safety and Efficacy of CAR-T Cells in the Treatment of Refractory Myasthenia Gravis CD19 CAR-T cells injection - Myasthenia Gravis | Phase 1 | Unknown | Zhejiang University | 9 | 2023-04-30 | 2023-04-25 |
| Dose-escalation by Hypofractionated Stereotactic Radiotherapy for Brain Metastases in Non Small Cell Lung Cancer Hypofractionated Stereotactic Radiotherap - Non Small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer | Phase 1 / Phase 2 | Unknown | First People's Hospital of Hangzhou | 21 | 2022-01-01 | 2022-10-20 |
| Prehabilitation, Rehabilitation and Comprehensive Approach to the Sequelae of Brain Tumors Non-invasive neuromodulation (TMS and/or tDCS) - Brain Tumor | Phase 1 | Unknown | Institut Guttmann | 20 | 2021-06-21 | 2023-05-06 |
| Cytoprotective Effect and Clinical Outcome of Perioperative Proesterone in Brain Tumors Progesteron - Diffuse Traumatic Cerebral Edema | Phase 1 | Unknown | Minia University | 26 | 2020-06-01 | 2020-06-04 |
| Pyrotinib Combined With Brain Radiotherapy in Breast Cancer Patients With Brain Metastases Pyrotinib Plus Capecitabine combined with brain radiotherapy - Breast Cancer, Brain Metastases | Phase 1 / Phase 2 | Unknown | Fudan University | 39 | 2020-01-02 | 2023-01-18 |
| Combination of Alpelisib and Trametinib in Progressive Refractory Meningiomas Trametinib, Alpelisib, Blood sample - Meningioma | Phase 1 | Unknown | Assistance Publique Hopitaux De Marseille | 25 | 2019-09-30 | 2024-08-06 |
| Dendritic Cell Therapy for Brain Metastases From Breast- or Lung Cancer DCVax-Direct - Brain Metastases, Lung Cancer Metastatic | Phase 1 | Unknown | Northwest Biotherapeutics | 24 | 2018-11-01 | 2018-08-20 |
| Phase I Clinical Study of GB222 to Evaluate the Safety, Tolerability and PK Profiles. GB222 3mg/kg, GB222 5mg/kg, GB222 7.5mg/kg - Brain Tumor | Phase 1 | Unknown | Genor Biopharma Co., Ltd. | 24 | 2018-10-16 | 2019-11-27 |
| Fractionated Stereotactic Radiosurgery With Concurrent Bevacizumab for Brain Metastases: A Phase I Dose-escalation Trial Fractionated stereotactic radiosurgery, bevacizumab - Brain Neoplasm | Phase 1 | Unknown | National Taiwan University Hospital | 36 | 2018-01-01 | 2017-08-18 |
| Safety and Efficacy of the ONCOlytic VIRus Armed for Local Chemotherapy, TG6002/5-FC, in Recurrent Glioblastoma Patients Combination of TG6002 and 5-flucytosine (5-FC, Ancotil®) - Glioblastoma, Brain Cancer | Phase 1 / Phase 2 | Unknown | Assistance Publique - Hôpitaux de Paris | 78 | 2017-10-12 | 2017-11-06 |
| Safety Study of DIPG Treatment With Autologous Dendritic Cells Pulsed With Lysated Allegenic Tumor Lines Autologous dendritic cells - Diffuse Intrinsic Pontine Glioma | Phase 1 | Unknown | Fundació Sant Joan de Déu | 10 | 2016-06-01 | 2018-03-02 |
| Demeclocycline Fluorescence for Intraoperative Delineation Brain Tumors Demeclocycline - Brain Tumor | Phase 1 | Unknown | Massachusetts General Hospital | 40 | 2016-04-01 | 2016-04-15 |
| Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy Partial brain re-irradiation., Metformin, low carbohydrate diet - Brain Neoplasms | Phase 1 | Unknown | Sheba Medical Center | 18 | 2014-06-01 | 2017-10-27 |
| Hyperbaric Oxygen Therapy Can Improve Neurological State Post Meningioma Removal Surgery HBOT - Intracranial Meningioma, Neurologic Deficits | Phase 1 | Unknown | Assaf-Harofeh Medical Center | 62 | 2014-04-01 | 2014-03-12 |
| The Use of 5-aminolevulinic Acid (ALA) as an Intraoperative Tumor Marker for Resection of Pediatric Central Nervous System (CNS) Tumors 5ALA - Central Nervous System Tumor, Pediatric | Phase 1 / Phase 2 | Unknown | Tel-Aviv Sourasky Medical Center | 100 | 2014-02-01 | 2014-01-30 |
| Autologous Dendritic Cell Vaccine in Patients With Soft Tissue Sarcoma Autologous dendritic cell vaccine - Sarcoma, Neoplasms, Connective and Soft Tissue | Phase 1 / Phase 2 | Unknown | N.N. Petrov National Medical Research Center of Oncology | 48 | 2013-06-01 | 2019-11-20 |
| Detection of Functioning Pituitary Microadenoma: PET/MRI Versus PET/CT 18F-FDG - Pituitary Adenoma | Phase 1 | Unknown | Peking Union Medical College Hospital | 100 | 2013-02-01 | 2018-01-19 |
| Synchrotron Radiation to the Treatment of Intracranial Tumors treated by synchrotron radiation - Brain Cancer | Phase 1 / Phase 2 | Unknown | University Hospital, Grenoble | 50 | 2012-06-01 | 2013-11-11 |
| Frameless Stereotactic Radiosurgery for Brain Metastases Frameless Stereotactic Radiosurgery with radiation mask - Brain Metastases | Phase 1 / Phase 2 | Unknown | Alberta Health services | 20 | 2010-01-01 | 2011-11-22 |
| Exercise for Stable Myasthenia Gravis Exercise - Myasthenia Gravis | Phase 1 | Unknown | Baltimore VA Medical Center | 30 | 2010-01-01 | 2016-11-01 |
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Brain Neoplasms (27) · Central Nervous System Neoplasms (14) · Glioblastoma (13) · Astrocytoma (11) · Gliosarcoma (9) · Oligodendroglioma (7) · Glioma (6) · Neoplasm Metastasis (5) · Ependymoma (4) · Meningioma (3) · Carcinoma, Non-Small-Cell Lung (2) · Choroid Plexus Neoplasms (2) · Familial ependymoma (2) · Glioma, Subependymal (2) · Lung Neoplasms (2)
Nervous System Diseases (39) · Neoplasms (38) · Neoplasms by Site (38) · Brain Diseases (30) · Central Nervous System Diseases (30) · Central Nervous System Neoplasms (22) · Neoplasms by Histologic Type (21) · Neoplasms, Nerve Tissue (19) · Neoplasms, Germ Cell and Embryonal (17) · Neoplasms, Glandular and Epithelial (16) · Neuroectodermal Tumors (16) · Neoplasms, Neuroepithelial (15) · Glioma (10) · Pathological Conditions, Signs and Symptoms (7)
Radiotherapy (4) · Temozolomide (4) · Chlorotoxin (2) · Alpelisib (1) · Amplified Fragment Length Polymorphism Analysis (1) · Arsenic Trioxide (1) · Bevacizumab (1) · Biguanides (1) · Blood Specimen Collection (1) · Brachytherapy (1) · Carboplatin (1) · Carmustine (1) · Cisplatin (1) · Demeclocycline (1) · Diet, Carbohydrate-Restricted (1)
Barrett Cancer Center (2) · European Organisation for Research and Treatment of Cancer - EORTC (2) · TransMolecular (2) · Alberta Health services (1) · Assaf-Harofeh Medical Center (1) · Assistance Publique - Hôpitaux de Paris (1) · Assistance Publique Hopitaux De Marseille (1) · Atlantic Health System (1) · Baltimore VA Medical Center (1) · Carl Zeiss Surgical GmbH (1) · Center for Molecular Medicine (1) · Children's Cancer and Leukaemia Group (1) · Copharos (1) · Direct Therapeutics (1) · First People's Hospital of Hangzhou (1)
United States (18) · China (5) · France (4) · Israel (3) · United Kingdom (3) · Canada (2) · Spain (2) · Egypt (1) · Ireland (1) · Russia (1) · Switzerland (1) · Taiwan (1)
Jeffrey Raizer, MD (2) · Ronald E. Warnick, MD (2) · Sean Grimm, MD (2) · Adam Mamelak, MD (1) · Alfredo Quinones Hinojosa, MB (1) · Antonio Omuro, MD (1) · Burt Nabors, MD (1) · Charlene E Hafer-Macko, MD (1) · Chia-Chun Wang (1) · Darren Hargrave, MD (1) · David Schiff, MD (1) · Edward Pan, MD (1) · G. Mead, MD (1) · Gene David Resnick, MD (1)
PMID 22291006, PMID 25614945, PMID 37849833, PMID 38175627, PMID 39024777
2015 (1)