7 completed, 1 active not recruiting, 1 not yet recruiting, 1 unknown. 6 Phase 4, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 4, Not yet recruiting 1, Unknown 1 |
| Not applicable | 1 | Completed 1 |
Follow Neostigmine: new trials by email Literature Review of Neostigmine trials Research Report on Neostigmine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NMBA Reversal and Postoperative Urinary Retention Choice of reversal agent (sugammadex or neostigmine [with muscaranic antagonist]) - Neuromuscular Blocking Agents, Urinary Retention After Procedure | Active not recruiting | Beth Israel Deaconess Medical Center | 70000 | 2025-06-08 | 2026-01-23 | |
| Comparative Study Between Intrathecal Magnesium Sulfate, Neostigmine and Fentanyl as Adjuvant for Bubivacaine in Postoperative Analgesia in Lower Abdominal Surgeries Magnesium Sulfate and Bupivacaine 0.125%, bupivacaine and Neostigmine, fentanyl and bupivacaine - Magnesium Sulfate, Neostigmine | Phase 4 | Not yet recruiting | Assiut University | 66 | 2024-12-01 | 2024-11-12 |
| Postoperative Urinary Retention After Reversal of Neuromuscular Block by Neostigmine Versus Sugammadex Neostigmine, Sugammadex - Urinary Retention Postoperative, Laparoscopic Cholecystectomy | Phase 4 | Completed | University of Texas Southwestern Medical Center | 235 | 2023-09-11 | 2024-10-09 |
| Sugammadex and Time to Extubation in Ophthalmic Surgery sugammadex, Neostigmine + Atropine - General Anesthesia Using Endotracheal Intubation, Ophthalmologic Surgical Procedure | Completed | China Medical University Hospital | 262 | 2023-08-01 | 2024-10-08 | |
| Neostigmine Versus Sugammadex on Renal Functions Neostigmine, Sugammadex - Sugammadex, Neostigmine | Phase 4 | Unknown | Menoufia University | 64 | 2023-03-01 | 2023-10-13 |
| Reversal of Moderate or Superficial Neuromuscular Blockade Induced by Cisatracurium Reversal of moderate neuromuscular blockade, Reversal of superficial neuromuscular blockade, Two-step reversal - Neostigmine, Neuromuscular Blocking Agents | Phase 4 | Completed | Pontificia Universidade Catolica de Sao Paulo | 60 | 2021-06-01 | 2022-05-19 |
| Comparison of QoR-15 in Laparoscopic Cholecystectomy: Sugammadex vs. Neostigmine Sugammadex, Neostigmine - Neuromuscular Blockade Reversal Agent, Sugammadex | Phase 4 | Completed | Seoul National University Bundang Hospital | 77 | 2020-02-24 | 2020-12-24 |
| Observational Study in Bariatric Surgery NO INTERVENTION, it is an observational study - Obesity, Neostigmine | Completed | Poitiers University Hospital | 140 | 2020-01-29 | 2023-07-06 | |
| Can we Antagonize Mivacurium With Neostigmine ? Neostigmine (40 mcg / kg) at different time of neuromuscular block's recovery, Spontaneous recovery - Mivacurium, Neostigmine | Not applicable | Completed | Université Libre de Bruxelles | 80 | 2016-12-01 | 2017-05-19 |
| Residual Paralysis and Reversal With Routine Neostigmine Versus Half-dose Sugammadex and Routine Neostigmine Neostigmine, Sugammadex - Neuromuscular Blockade, Sugammadex | Phase 4 | Completed | Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital | 113 | 2013-05-01 | 2021-10-04 |
Delayed Emergence from Anesthesia (2) · Muscle Weakness (1) · Obesity (1) · Urinary Retention (1)
Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Postoperative Complications (2) · Signs and Symptoms (2) · Body Weight (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Male Urogenital Diseases (1) · Muscular Diseases (1) · Musculoskeletal Diseases (1) · Nervous System Diseases (1) · Neurologic Manifestations (1) · Neuromuscular Manifestations (1) · Nutrition Disorders (1) · Nutritional and Metabolic Diseases (1)
Neostigmine (8) · Sugammadex (6) · Atropine (1) · Bupivacaine (1) · Fentanyl (1) · Magnesium Sulfate (1)
Assiut University (1) · Beth Israel Deaconess Medical Center (1) · China Medical University Hospital (1) · Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital (1) · Menoufia University (1) · Poitiers University Hospital (1) · Pontificia Universidade Catolica de Sao Paulo (1) · Seoul National University Bundang Hospital (1) · University of Texas Southwestern Medical Center (1) · Université Libre de Bruxelles (1)
United States (2) · Belgium (1) · Brazil (1) · Egypt (1) · France (1) · South Korea (1) · Taiwan (1)
Eduardo T Moro, MD (1) · Jiwon Han, Ms (1) · Luca J Wachtendorf, MD (1) · Maximilian S Schaefer, MD, PhD (1) · Tiffany Moon, MD (1) · Yi-Ying Chiang, MD (1)
PMID 10719950, PMID 16183681, PMID 20876699, PMID 20885293, PMID 26634077, PMID 27746548, PMID 28399799, PMID 29284839, PMID 30622224, PMID 31362883, PMID 32024465, PMID 35016456, PMID 35803751, PMID 37601044, PMID 38429736, PMID 41789933, PMID 7880668