13 completed, 6 unknown, 1 terminated. 2 Phase 1, 1 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 2 |
| Not applicable | 1 | Completed 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Narcotic Abuse: new trials by email Literature Review of Narcotic Abuse trials Research Report on Narcotic Abuse
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries Questionnaire - Narcotic Use, Postoperative Pain | Completed | St. Louis University | 223 | 2017-11-16 | 2021-09-24 | |
| A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Opioids for the Treatment of Chronic Pain Observation Only - Opioid-Related Disorders, Opiate Addiction | Completed | Member Companies of the Opioid PMR Consortium | 3600 | 2017-11-01 | 2025-01-29 | |
| Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain Structured discontinuation of opioid therapy (morphine sulfate ER, oxycodone ER, oxymorphone ER), Continuation of opioid therapy (morphine sulfate ER, oxycodone ER, oxymorphone ER) - Opioid-Related Disorders, Opiate Addiction | Phase 4 | Terminated | Member Companies of the Opioid PMR Consortium | 44 | 2016-09-14 | 2019-11-06 |
| Validation of PRISM-5-Op, Measure Of Addiction To Prescription Opioid Medication Psychiatric Research Interview for Substance and Mental Disorders (PRISM-5-Op) - Opioid-Related Disorders, Opiate Addiction | Completed | Member Companies of the Opioid PMR Consortium | 606 | 2015-11-17 | 2020-06-16 | |
| An Observational Study to Develop Algorithms for Identifying Opioid Abuse and Addiction Based on Admin Claims Data Algorithm to identify patients experiencing opioid abuse/addiction - Opioid-Related Disorders, Opiate Addiction | Completed | Member Companies of the Opioid PMR Consortium | 1667 | 2015-05-20 | 2020-04-15 | |
| Study to Validate Coded Medical Terms Used to Identify Opioid-Related Overdose in Databases Used for PMR Study 1B Algorithm to determine overdose from opioid abuse - Opioid-Related Disorders, Opiate Addiction | Completed | Member Companies of the Opioid PMR Consortium | 2701 | 2015-04-07 | 2020-04-15 | |
| A Quantitative Study to Assess the Construct Validity of the Prescription Opioid Misuse and Abuse Questionnaire Prescription Opioid Misuse and Abuse Questionnaire (POMAQ) - Opioid-Related Disorders, Opiate Addiction | Completed | Member Companies of the Opioid PMR Consortium | 800 | 2015-04-07 | 2020-04-15 | |
| Cross-Sectional Study to Define and Validate "Doctor/Pharmacy Shopping" as Outcomes Suggestive of Abuse and/or Addiction DB review for Doctor/Pharmacy Shopping Behavior - Opioid-Related Disorders, Opiate Addiction | Completed | Member Companies of the Opioid PMR Consortium | 164923 | 2015-02-05 | 2020-04-15 | |
| A Qualitative Study to Assess the Content Validity of the Prescription Opioid Misuse and Abuse Questionnaire Prescription Opioid Misuse and Abuse Questionnaire (POMAQ) - Opioid-Related Disorders, Opiate Addiction | Completed | Member Companies of the Opioid PMR Consortium | 54 | 2015-01-02 | 2020-04-15 | |
| A Survey to Eval the Relation Between Doctor/Pharmacy Shopping and Outcomes Suggestive of Misuse, Abuse and/or Diversion Survey to Eval Relation between Shopping and Misuse, Abuse - Opioid-Related Disorders, Opiate Addiction | Completed | Member Companies of the Opioid PMR Consortium | 1085 | 2014-11-07 | 2020-04-15 | |
| Study to Eval Relation Btw Doctor/Pharmacy Shopping & Outcomes of Misuse, Diversion, Abuse, Addiction by Med Rec Review Medical Record Review - Opioid-Related Disorders, Opiate Addiction | Completed | Member Companies of the Opioid PMR Consortium | 590 | 2014-11-06 | 2020-04-15 | |
| Abuse Potential Assessment of Intranasally Administered EMBEDA Compared To Morphine Sulfate Controlled Release And Placebo Placebo, EMBEDA - morphine sulfate/ naltrexone hydrochloride, morphine sulfate CR crushed. - Narcotic Abuse, Opioid-related Disorders | Phase 1 | Completed | Pfizer | 33 | 2010-08-01 | 2012-06-08 |
| A Clinical Study To Characterize The Pharmacokinetics And The Effects Of Food On Oxycodone In Healthy Volunteers oxycodone hydrochloride, marketed oxycodone hydrochloride - Analgesia, Acute Pain | Phase 1 | Completed | Pfizer | 35 | 2010-07-01 | 2012-02-24 |
| Aprepitant Effects on Oxycodone Response Aprepitant 0mg, Aprepitant 40mg, Aprepitant 200mg - Narcotic Abuse | Not applicable | Completed | Sharon Walsh | 9 | 2009-10-01 | 2017-09-01 |
| Evaluation of Drug Utilization Patterns for Extended Release/Long Acting Opioids and Comparator Products Non-interventional study - retrospective database review - Opioid Related Disorders, Opiate Addiction | Unknown | ER/LA Opioid REMS Program Companies (RPC) | 5575834 | 2016-10-06 | ||
| ER/LA Opioid Surveillance for Emergency Department Visits and Hospitalizations for Overdose and Poisoning Retrospective database review - Opioid-related Disorders, Opioid Addiction | Unknown | ER/LA Opioid REMS Program Companies (RPC) | 183452 | 2016-10-05 | ||
| Monitoring Patterns of Prescribing to Identify Changes in Access to ER/LA Opioid Analgesics Non-interventional study - retrospective database review - Opioid Related Disorders, Opiate Addiction | Unknown | ER/LA Opioid REMS Program Companies (RPC) | 360000 | 2016-09-30 | ||
| Evaluation of Changes in Prescribing Behavior of ER/LA Opioid Prescribers on-interventional study - retrospective database review - Opioid Related Disorders, Opiate Addiction | Unknown | ER/LA Opioid REMS Program Companies (RPC) | 5575834 | 2016-09-30 | ||
| ER/LA Opioid Analgesics - Surveillance Monitoring of State Medical Examiner Databases Surveillance of state medical examiner databases - Opioid-related Disorders, Opioid Addiction | Unknown | ER/LA Opioid REMS Program Companies (RPC) | 13015 | 2016-09-13 | ||
| Surveillance Monitoring of Opioid Abuse in Poison and Drug Treatment Centers Researched Abuse, Diversion and Addiction-Related Surveillance (RADARS) System of post-marketing surveillance of prescription medication abuse, misuse, and diversion - Opioid-related Disorders, Opioid Addiction | Unknown | ER/LA Opioid REMS Program Companies (RPC) | 26500 | 2016-08-25 |
Narcotic-Related Disorders (20) · Opioid-Related Disorders (19) · Substance-Related Disorders (16) · Agnosia (2) · Chronic Pain (2) · Acute Pain (1) · Musculoskeletal Diseases (1) · Pain, Postoperative (1) · Recreational Drug Use (1)
Chemically-Induced Disorders (20) · Mental Disorders (20) · Substance-Related Disorders (4) · Neurologic Manifestations (3) · Pain (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2) · Behavior (1) · Pathologic Processes (1) · Postoperative Complications (1)
Oxycodone (2) · Aprepitant (1) · Naltrexone (1) · Surveys and Questionnaires (1)
Member Companies of the Opioid PMR Consortium (10) · ER/LA Opioid REMS Program Companies (RPC) (6) · Pfizer (2) · Sharon Walsh (1) · St. Louis University (1)
United States (6)
Soledad Cepeda, MD, PhD (3) · Alexandra Barsdorf, Ph.D. (2) · Kenneth R Petronis (2) · Paul Coplan, MS, ScD, MBA (2) · John M Capelle, MD (1) · Sharon L Walsh, Ph.D. (1)
PMID 22260216, PMID 22717418, PMID 23936895, PMID 27869630, PMID 31020755, PMID 31095831, PMID 31218780, PMID 31534380, PMID 32489718, PMID 35437075, PMID 35702830
R01DA027031 (1)