5 recruiting, 3 not yet recruiting, 1 completed. 4 Phase 1, 3 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Recruiting 3, Not yet recruiting 1 |
| Not applicable | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 2 | Not yet recruiting 1, Recruiting 1 |
Follow Multiple Sclerosis (MS) Secondary Progressive: new trials by email Literature Review of Multiple Sclerosis (MS) Secondary Progressive trials Research Report on Multiple Sclerosis (MS) Secondary Progressive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Remibrutinib Using MR Imaging in Relapsing or Progressive MS Remibrutinib (Open Label) - Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Secondary Progressive | Phase 2 | Not yet recruiting | Moein Amin | 20 | 2027-03-01 | 2026-08-19 |
| Acute Intermittent Hypoxia Combined With Gait Training in Multiple Sclerosis Acute Intermittent Hypoxia (AIH), Sham Acute Intermittent Hypoxia (AIH), Myoelectric Interface Neurorehabilitation Training (MINT) - Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting | Not applicable | Not yet recruiting | Shirley Ryan AbilityLab | 35 | 2026-06-15 | 2026-06-08 |
| Safety and Efficacy of S103 Cells in Progressive/Refractory Multiple Sclerosis S103 cells - Multiple Sclerosis (MS) Primary Progressive, Multiple Sclerosis | Phase 1 | Recruiting | Xijing Hospital | 9 | 2026-05-08 | 2026-08-05 |
| Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis TRX319, Bendamustine - Primary Progressive Multiple Sclerosis, Secondary Progressive Multiple Sclerosis (SPMS) | Phase 1 / Phase 2 | Recruiting | Tr1X, Inc. | 39 | 2026-03-01 | 2026-09-21 |
| Senolytics for Secondary Progressive MS Dasatinib and quercetin - Multiple Sclerosis (MS) Secondary Progressive | Phase 1 | Not yet recruiting | Ohio State University | 30 | 2026-01-15 | 2025-12-08 |
| Home Based Functional Balance Intervention for Multiple Sclerosis Multicomponent balance intervention consisting of four components including dual-tasking, functional strength, vestibular and dynamic balance., Stretching - Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting | Not applicable | Recruiting | University of Illinois at Chicago | 75 | 2025-11-24 | 2026-01-21 |
| "Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting | Recruiting | University of California, San Francisco | 300 | 2025-10-01 | 2025-10-31 | |
| Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases HBI0101 CART - Systemic Sclerosis (SSc), Idiopathic Inflammatory Myopathy (IIM) | Phase 1 | Recruiting | Polina Stepensky | 120 | 2024-09-01 | 2026-05-06 |
| Social Cognition in Multiple Sclerosis, From a Study of Eye Movement and Gaze Strategies Using Video-oculography Video-oculography / Social cognition tasks / Neuropsychological evaluations - Multiple Sclerosis (MS), Multiple Sclerosis (MS) Relapsing Remitting | Not applicable | Completed | Association de Recherche Bibliographique pour les Neurosciences | 76 | 2017-05-23 | 2021-01-22 |
Multiple Sclerosis (9) · Multiple Sclerosis, Chronic Progressive (9) · Multiple Sclerosis, Relapsing-Remitting (5) · Antiphospholipid Syndrome (1) · Arthritis, Rheumatoid (1) · Cognitive Dysfunction (1) · Demyelinating Diseases (1) · Hypoxia (1) · Lupus Erythematosus, Systemic (1) · Myasthenia Gravis (1) · Myositis (1) · Neuromyelitis Optica (1) · Recurrence (1) · Scleroderma, Systemic (1)
Autoimmune Diseases (9) · Autoimmune Diseases of the Nervous System (9) · Chronic Disease (9) · Demyelinating Autoimmune Diseases, CNS (9) · Disease Attributes (9) · Immune System Diseases (9) · Nervous System Diseases (9) · Pathologic Processes (9) · Pathological Conditions, Signs and Symptoms (9) · Demyelinating Diseases (8) · Arthritis (1) · Cognition Disorders (1) · Connective Tissue Diseases (1) · Cranial Nerve Diseases (1) · Eye Diseases (1)
Bendamustine Hydrochloride (1) · Dasatinib (1) · Quercetin (1) · remibrutinib (1)
Association de Recherche Bibliographique pour les Neurosciences (1) · Moein Amin (1) · Ohio State University (1) · Polina Stepensky (1) · Shirley Ryan AbilityLab (1) · Tr1X, Inc. (1) · University of California, San Francisco (1) · University of Illinois at Chicago (1) · Xijing Hospital (1)
United States (5) · China (1) · Israel (1) · Monaco (1)
Milap Sandhu, PT, PhD (1) · Moein Amin, MD, MS (1) · Riley Bove, MD (1)