80 completed, 48 unknown, 35 recruiting, 19 not yet recruiting. 71 Not applicable, 41 Phase 2, 18 Phase 1, 15 Phase 3, 7 Phase 4.
Follow Morphological and Microscopic Findings: new trials by email Literature Review of Morphological and Microscopic Findings trials Research Report on Morphological and Microscopic Findings
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Papilozumib Vaginal Gel for Exocervical Mucosal Restoration in Women With Human Papillomavirus (HPV) Papilozumib vaginal gel, Papilozumib oral supplement - Human Papillomavirus Infection, Human Papillomavirus Infections | Not applicable | Not yet recruiting | Hifas da Terra S.L. | 81 | 2027-07-01 | 2026-10-05 |
| Biomechanical Characterization of Skin Properties Using Impact Based-Analysis Method (IBAM) Melanoma (Skin Cancer), Skin Carcinoma | Not yet recruiting | Centre Hospitalier Universitaire Henri Mondor, Assistance Publique Hôpitaux de Paris | 10 | 2026-12-03 | 2026-10-06 | |
| Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV Dose Level 1 ACU-D1 ointment, Dose Level 2 ACU-D1 ointment, Dose Level 3 ACU-D1 ointment - Human Papilloma Virus, Human Immunodeficiency Virus | Phase 1 | Not yet recruiting | Emory University | 9 | 2026-12-01 | 2026-08-18 |
| PIRe 2.0: A Stepped-Care Model for Involving Relatives Across Sectors Supportive Care - Brain Injuries, Acute, Brain Tumor Adult | Not applicable | Not yet recruiting | Copenhagen University Hospital, Rigshospitalet | 160 | 2026-10-01 | 2026-05-19 |
| Efficacy and Safety of Topical Timolol in Secondary Intention Surgical Wounds Healing Timolol 0.5% Ophthalmic Solution, Hydrogel of placebo - Mohs Micrographic Surgery, Excision Margin | Phase 2 | Not yet recruiting | University of California, Davis | 220 | 2026-10-01 | 2026-08-18 |
| Predictive Biomarkers for Precision Management of Pre-cancerous Cervical Neoplasia DNA methylation - HSIL, High Grade Squamous Intraepithelial Lesion, DNA Methylation | Active not recruiting | Lund University | 199 | 2026-09-19 | 2026-10-26 | |
| CASCADE 2002: PROTECT Study, "PRObiotics to TrEat Anal preCancer Trial EXE-346 Probiotic, Placebo, Usual Care High Resolution Anoscopy (HRA) - HSIL, High Grade Squamous Intraepithelial Lesion, HPV-Related Squamous Cell Carcinoma | Phase 2 | Recruiting | University of California, San Francisco | 90 | 2026-09-04 | 2026-10-29 |
| Ultrasound-Guided Versus Standard Margin Selection in Ileocecal Resection of Terminal Ileal CD IOUS-guided margin selection - Crohn's Disease (CD) | Not applicable | Recruiting | The Cleveland Clinic | 22 | 2026-09-01 | 2026-08-27 |
| HISMAR: Intraoperative Margin Assessment Using the Histolog® Scanner to Reduce Reoperation in Breast-Conserving Surgery Histolog® Scanner - Breast Cancer, Ductal Carcinoma In Situ | Not applicable | Not yet recruiting | Hôpital du Valais | 228 | 2026-09-01 | 2026-04-14 |
| Hair Regrowth Following Partial Thickness Removal of SSCIS Partial Thickness Excision - Squamous Cell Carcinoma (Skin), Squamous Cell Carcinoma in Situ | Not applicable | Not yet recruiting | The Cooper Health System | 15 | 2026-09-01 | 2026-09-09 |
| SPECTRA: Intraoperative Hyperspectral Imaging for Prostate Cancer HyperSpectral imaging acquisition of ex-vivo prostate specimen prior formalin fixation (fresh acquisition).. - Localized Prostate Cancer, Positive Surgical Margin | Not applicable | Recruiting | Massimo Valerio | 26 | 2026-08-01 | 2026-09-17 |
| Evaluation of NWRD09 for HPV-16 Related Cervical HSIL NWRD09 Injection, NWRD09 Placebo - High-grade Squamous Intraepithelial Lesion (HSIL) | Phase 2 | Not yet recruiting | Newish Biotech (Wuxi) Co., Ltd. | 156 | 2026-08-01 | 2026-07-17 |
| Individualized Primary Clinical Target Volume Based on Margin Expansion for Nasopharyngeal Carcinoma Comprehensive Therapy Based on Tumor Stage, IMRT with Primary Clinical Target Volume Based on Margin Expansion, IMRT with Consensus Primary Clinical Target Volume - Non-metastatic Nasopharyngeal Carcinoma | Phase 3 | Recruiting | Sun Yat-sen University | 568 | 2026-07-24 | 2026-08-19 |
| Hexaminolevulinate Photodynamic Therapy (HAL-PDT) With Deferred Surgery Versus Surgery for High-grade Squamous Intraepithelial Lesions (HSIL) Loop Electrosurgical Excision Procedure (LEEP) or Cold Knife Conization (CKC), HAL 5% with illumination - Cervical Intraepithelial Neoplasia, Papillomavirus Infections | Phase 2 | Not yet recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 230 | 2026-07-01 | 2026-07-09 |
| Defining the Ablative Dose for Y-90 TARE Yttrium-90 Radiation Segmentectomy (Y90 RS) using glass microspheres - HCC - Hepatocellular Carcinoma | Phase 2 | Recruiting | Northwestern University | 30 | 2026-05-15 | 2026-09-15 |
| Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors Indocyanine Green (ICG) - Squamous Cell Carcinoma Head and Neck Cancer (HNSCC), Margin Assessment | Phase 2 | Recruiting | Medical University of South Carolina | 30 | 2026-05-04 | 2026-07-07 |
| Trial to Evaluate Nonavalent HPV Vaccine as a Secondary Prevention in Patients Treated for Human Papilloma Virus Related High-grade Squamous Intraepithelial Lesions HPV vaccine, Placebo vaccine - Patients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Vulvar Site, Patients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Vaginal Site | Phase 3 | Not yet recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 984 | 2026-05-01 | 2026-02-27 |
| Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities EGCG and Quinine Sulfate Vaginal Suppository, Placebo - High-risk HPV (Any Strain), LSIL, Low Grade Squamous Intraepithelial Lesion | Phase 2 | Recruiting | Amplexd Therapeutics, Inc. | 45 | 2026-04-30 | 2026-05-14 |
| Dual-Modality Immunotherapy for HPV Clearance (DUAL-HPV) Oral Immunomodulator, Vaginal Ovule, Standard Supportive Care - Human Papillomavirus Infection, Cervical Intraepithelial Neoplasia (CIN) | Not applicable | Active not recruiting | Dr. Lutfi Kirdar Kartal Training and Research Hospital | 76 | 2026-04-28 | 2026-07-29 |
| A Study to Evaluate the Performance of Confocal Microscopy to Detect Positive Margins During Radical Prostatectomy LaserSAFE - Prostate Cancer, Prostate Cancer (Adenocarcinoma) | Not applicable | Recruiting | University College, London | 693 | 2026-04-20 | 2026-05-18 |
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Squamous Intraepithelial Lesions (93) · Margins of Excision (92) · Uterine Cervical Dysplasia (38) · Papillomavirus Infections (34) · Uterine Cervical Neoplasms (30) · Atypical Squamous Cells of the Cervix (28) · Breast Neoplasms (17) · Anus Neoplasms (12) · Carcinoma, Squamous Cell (12) · Adenocarcinoma in Situ (11) · Precancerous Conditions (11) · Recurrence (10) · Neoplasms (9) · Prostatic Neoplasms (8) · Acquired Immunodeficiency Syndrome (6)
Pathological Conditions, Signs and Symptoms (214) · Neoplasms (149) · Neoplasms by Site (113) · Urogenital Diseases (94) · Genital Diseases (91) · Female Urogenital Diseases (68) · Female Urogenital Diseases and Pregnancy Complications (68) · Genital Diseases, Female (64) · Uterine Diseases (62) · Uterine Cervical Diseases (61) · Pathologic Processes (54) · Neoplasms by Histologic Type (49) · Precancerous Conditions (48) · Disease Attributes (45)
Biopsy (4) · Colposcopy (4) · DNA Methylation (4) · Imiquimod (4) · VGX-3100 (4) · Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18 (3) · Laser Therapy (3) · Light Coagulation (3) · Observation (3) · Watchful Waiting (3) · 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone (2) · Aminolevulinic Acid (2) · Cidofovir (2) · Conization (2) · Dermoscopy (2)
AIDS Malignancy Consortium (8) · Fujian Maternity and Child Health Hospital (5) · Antiva Biosciences (4) · Lei Li (4) · Inovio Pharmaceuticals (3) · National Cancer Institute (NCI) (3) · Newish Biotech (Wuxi) Co., Ltd. (3) · Peking University People's Hospital (3) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (3) · Aarhus University Hospital (2) · Centre Hospitalier Universitaire, Amiens (2) · Copenhagen University Hospital, Rigshospitalet (2) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (2) · GlaxoSmithKline (2) · Gynecologic Oncology Group (2)
United States (67) · China (41) · Spain (13) · France (10) · Belgium (9) · Puerto Rico (9) · United Kingdom (9) · Canada (8) · Germany (7) · South Korea (7) · Italy (6) · Mexico (5) · South Africa (5) · Sweden (5) · Brazil (4)
Joel Palefsky, MD (5) · Jeffrey Skolnik, MD (3) · Cynthia J Goldberg, MD (2) · Elizabeth Stier, MD (2) · Keith A Aqua, MD (2) · Lei Li, M.D. (2) · Leopoldo E Gatica-Galina, MD in OB/GY & Gynecol Oncol (2) · Mark H Einstein, MD (2) · Mark S Nestor, MD, PhD (2) · Pengming Sun (2) · Pengming Sun, PhD (2) · Robert Pfeffer, MD (2)
PMID 33538338, PMID 35288319, PMID 14575828, PMID 16982773, PMID 17960012, PMID 18630456, PMID 18784101, PMID 19524035, PMID 19672942, PMID 20812850, PMID 20852198, PMID 21233014, PMID 21437225, PMID 21714641, PMID 22026481, PMID 22072149, PMID 22298678, PMID 22327172, PMID 22791786, PMID 23032420, PMID 23110817, PMID 23618600, PMID 23914987, PMID 24118526, PMID 24458427, PMID 24780112, PMID 25049329, PMID 25528723, PMID 25851632, PMID 26083247, PMID 26178760, PMID 26687616, PMID 26991020, PMID 27526956, PMID 27588192, PMID 27843625, PMID 28189914, PMID 28332888, PMID 28490940, PMID 28533474, PMID 28857936, PMID 29304768, PMID 29658848, PMID 29658856, PMID 29851256, PMID 30048762, PMID 30060087, PMID 30098677, PMID 30122563, PMID 30171396
U01CA121947 (6), 2008 (2), 2025 (2), UM1CA121947 (2), 2009 (1), 2014 (1), 2015 (1), 2016 (1), 2017 (1), 2018 (1), 2019 (1), P01CA082710 (1), P30CA015704 (1), P30CA060553 (1), R01CA111187 (1)