4 completed, 2 terminated. 6 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 4, Terminated 2 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating Clearance of High-Risk HPV and Safety After Administration of ABI-2280 Vaginal Inserts ABI-2280 - Human Papillomavirus Infection | Phase 1 / Phase 2 | Completed | Antiva Biosciences | 141 | 2024-03-27 | 2026-08-17 |
| A Study of ABI-2280 Vaginal Insert (Previously Referred to as ABI-2280 Vaginal Tablet) in Participants With Cervical Intraepithelial Neoplasia ABI-2280 Vaginal Tablet/Insert - Cervical Intraepithelial Neoplasia | Phase 1 / Phase 2 | Terminated | Antiva Biosciences | 44 | 2022-09-10 | 2026-02-19 |
| Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection. Topical ABI-1968 - HSIL of Cervix, HSIL, High Grade Squamous Intraepithelial Lesions | Phase 1 | Completed | Antiva Biosciences | 8 | 2018-12-21 | 2021-01-13 |
| Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection Topical ABI-1968 cream - HSIL, High-Grade Squamous Intraepithelial Lesions, Human Papilloma Virus Infection | Phase 1 | Terminated | Antiva Biosciences | 6 | 2018-12-17 | 2019-07-24 |
| Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection ABI-1968 - HSIL, HSIL of Cervix | Phase 1 | Completed | Antiva Biosciences | 16 | 2018-01-01 | 2019-07-10 |
| Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection ABI-1968 - HSIL, High-Grade Squamous Intraepithelial Lesions, Human Papilloma Virus Infection | Phase 1 | Completed | Antiva Biosciences | 57 | 2017-08-11 | 2019-02-07 |
Squamous Intraepithelial Lesions (4) · Papillomavirus Infections (3) · Uterine Cervical Dysplasia (3) · Anus Neoplasms (2) · HIV Infections (2) · Uterine Cervical Neoplasms (2) · Sexually Transmitted Diseases (1)
Australia (5) · United States (3) · South Africa (2) · Kenya (1) · Mexico (1) · New Zealand (1) · Peru (1)