12 completed, 4 terminated, 4 unknown, 3 recruiting. 9 Not applicable, 8 Phase 2, 3 Phase 1, 1 Phase 3, 1 Phase 4.
Follow Atypical Squamous Cells of the Cervix: new trials by email Literature Review of Atypical Squamous Cells of the Cervix trials Research Report on Atypical Squamous Cells of the Cervix
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Papilozumib Vaginal Gel for Exocervical Mucosal Restoration in Women With Human Papillomavirus (HPV) Papilozumib vaginal gel, Papilozumib oral supplement - Human Papillomavirus Infection, Human Papillomavirus Infections | Not applicable | Not yet recruiting | Hifas da Terra S.L. | 81 | 2027-07-01 | 2026-10-05 |
| Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities EGCG and Quinine Sulfate Vaginal Suppository, Placebo - High-risk HPV (Any Strain), LSIL, Low Grade Squamous Intraepithelial Lesion | Phase 2 | Recruiting | Amplexd Therapeutics, Inc. | 45 | 2026-04-30 | 2026-05-14 |
| Dual-Modality Immunotherapy for HPV Clearance (DUAL-HPV) Oral Immunomodulator, Vaginal Ovule, Standard Supportive Care - Human Papillomavirus Infection, Cervical Intraepithelial Neoplasia (CIN) | Not applicable | Active not recruiting | Dr. Lutfi Kirdar Kartal Training and Research Hospital | 76 | 2026-04-28 | 2026-07-29 |
| Comparison Of Cytology And Molecular Screening For Detecting Cervical Reactive Cellular Changes In General Population Physical examination, Liquid-based cytology, Molecular screening - Atypical Squamous Cell of Undetermined Significance, ASC-US | Not applicable | Withdrawn | Timser SAPI de CV | 2026-02-27 | 2026-03-03 | |
| Comparison Between Liquid-Based Cytology And Molecular Screening For Detecting Precursor Lesions and Cervical Cancer Physical examination, Liquid-based cytology, Molecular screening - I) Atypical Squamous Cells of Undetermined Significance (ASC-US), II) Atypical Glandular Cells of Uncertain Significance (AGUS) | Not applicable | Recruiting | Timser SAPI de CV | 558 | 2026-02-03 | 2026-03-18 |
| Study of Treatment for HPV16+ ASC-US or LSIL pNGVL4aCRTE6E7L2, TA-CIN - ASC-US, LSIL | Phase 1 | Recruiting | University of Alabama at Birmingham | 30 | 2023-07-10 | 2026-05-15 |
| Primary Cervical Cancer Screening by Self-sampling HPV Test Human Papillomavirus Infection, Cervical Cancer | Active not recruiting | Peking University People's Hospital | 17875 | 2022-11-19 | 2023-12-21 | |
| Clinical Evaluation of Detection of High Risk HPV in Urine Human Papillomavirus Infection, Cervical Cancer | Unknown | Peking University People's Hospital | 1000 | 2021-09-15 | 2022-01-27 | |
| "Lactobacillus Crispatus M247, LSIL and Microbiota" Lactobacillus Crispatus M247 - Vaginal Flora Imbalance, ASC-US | Phase 4 | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 90 | 2021-06-16 | 2023-04-11 |
| Phase II Study of Treatment for HPV16+ ASC-US, ASC-H and LSIL PVX-2, Placebo - ASC-US, ASC-H | Phase 2 | Terminated | PapiVax Biotech, Inc. | 16 | 2019-05-22 | 2024-06-17 |
| HPV Test of Urine and Self Collected Vaginal Samples for Cervical Cancer Screening Study Flocked Swab, Cervical Brush, HPV assay - ASC-US, LSIL | Unknown | Korea University Guro Hospital | 300 | 2018-05-04 | 2018-08-24 | |
| Zinc Sulfate for Human Papillomavirus (HPV) Zinc Sulfate, Placebo (Gelatin Tablet) - Human Papilloma Virus | Not applicable | Terminated | Corewell Health West | 21 | 2017-10-24 | 2023-09-22 |
| Safety, Tolerability, and Immunogenicity of GTL001 Vaccine Adjuvanted With Imiquimod Cream in HPV 16- and/or HPV 18-Infected Women Aged 25 to 65 Years, With Normal Cytology, ASCUS, or LSIL GTL001+, Aldara - HPV 16- and/or HPV 18-Infected Women With Normal Cytology, ASCUS, or LSIL | Phase 1 | Terminated | Genticel | 13 | 2015-08-01 | 2016-12-02 |
| Probiotic Implementation as Help in Solving Vaginal Infections Lactobacillus rhamnosus BMX 54 - Vaginal Infection, ASC-US | Phase 2 | Completed | University of Roma La Sapienza | 117 | 2015-02-01 | 2017-12-13 |
| Can B12 and Folate Levels Predict HPV Penetration in Patients With ASCUS? Vitamin B12 and folate - ASC-US, Human Papilloma Virus | Not applicable | Completed | Sanliurfa Mehmet Akif Inan Education and Research Hospital | 200 | 2014-05-01 | 2019-04-05 |
| Home-Based or Clinic-Based Human Papillomavirus (HPV) Screening Cervical Papanicolaou Test, Cytology Specimen Collection Procedure, Questionnaire Administration - Atypical Squamous Cell of Undetermined Significance, Cervical Carcinoma | Not applicable | Completed | University of Washington | 1335 | 2012-03-01 | 2020-07-31 |
| Evaluation of a New Vaccine Treatment for Patients With Metastatic Skin Cancer Immunotherapeutic GSK2302025A, different formulations - Melanoma | Phase 1 | Completed | GlaxoSmithKline | 107 | 2010-07-02 | 2020-11-20 |
| Study of GSK2132231A Antigen-Specific Cancer Immunotherapeutic in Patients With Inoperable Metastatic Cutaneous Melanoma Immunotherapeutic GSK2132231A - Melanoma | Phase 2 | Completed | GlaxoSmithKline | 24 | 2009-05-19 | 2021-04-08 |
| Clinical Evaluation of the APTIMA® HPV Assay Using the TIGRIS® System APTIMA HPV Assay, FDA-Approved HPV DNA Test - Human Papillomavirus Infection | Phase 3 | Completed | Gen-Probe, Incorporated | 12896 | 2008-03-01 | 2017-01-06 |
| Study of Pap Smears From Patients Enrolled on Clinical Trial GOG-171 Papanicolaou test, laboratory biomarker analysis - Cervical Cancer, Precancerous Condition | Unknown | Gynecologic Oncology Group | 55 | 2008-02-01 | 2010-11-08 |
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Uterine Cervical Dysplasia (14) · Papillomavirus Infections (13) · Uterine Cervical Neoplasms (13) · Squamous Intraepithelial Lesions (11) · Precancerous Conditions (6) · Adenocarcinoma in Situ (2) · Melanoma (2) · Candidiasis, Vulvovaginal (1) · Infections (1) · Neoplasms (1) · Vaginal Diseases (1) · Vaginitis (1)
Female Urogenital Diseases (28) · Female Urogenital Diseases and Pregnancy Complications (28) · Genital Diseases (28) · Genital Diseases, Female (28) · Morphological and Microscopic Findings (28) · Pathological Conditions, Signs and Symptoms (28) · Urogenital Diseases (28) · Uterine Cervical Diseases (28) · Uterine Diseases (28) · Neoplasms (27) · Precancerous Conditions (22) · Neoplasms by Site (15) · Uterine Cervical Dysplasia (14) · Communicable Diseases (13) · DNA Virus Infections (13)
Colposcopy (2) · Folic Acid (2) · Human Papillomavirus DNA Tests (2) · Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18 (2) · Restraint, Physical (2) · Biopsy (1) · Gelatin (1) · High-Throughput Screening Assays (1) · Imiquimod (1) · Immunologic Factors (1) · Mindfulness-Based Stress Reduction (1) · Papanicolaou Test (1) · Vaginal Smears (1) · Vitamin B 12 (1) · Zinc Sulfate (1)
GlaxoSmithKline (2) · Peking University People's Hospital (2) · Timser SAPI de CV (2) · University of Alabama at Birmingham (2) · University of Washington (2) · AIDS Malignancy Consortium (1) · Amplexd Therapeutics, Inc. (1) · Corewell Health West (1) · Dr. Lutfi Kirdar Kartal Training and Research Hospital (1) · Eisenhower Army Medical Center (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Fox Chase Cancer Center (1) · Gen-Probe, Incorporated (1) · Genticel (1) · Gynecologic Oncology Group (1)
United States (13) · China (2) · France (2) · Italy (2) · Mexico (2) · Belgium (1) · Canada (1) · Czechia (1) · Germany (1) · Hong Kong (1) · Poland (1) · Puerto Rico (1) · Russia (1) · Senegal (1) · South Korea (1)
Leopoldo E Gatica-Galina, MD in OB/GY & Gynecol Oncol (2) · Bonnie Spring, PhD (1) · Carolyn Fang, PhD (1) · Chandrika J. Piyathilake, PhD, MPH (1) · Dean A. Seehusen, MD, MPH (1) · Frank Meyskens (1) · Jae Kwan Lee, MD, Ph.D. (1) · Jennifer L Reid, PhD (1) · Joel Palefsky, MD (1) · Kar Kei Yung, MBBS (HK), MRCOG, FHKCOG, FHKA (1) · Keiichi Fujiwara, MD, PhD (1) · Mark Einstein, MD, MS (1) · Nancy B. Kiviat, MD (1)
PMID 20812850, PMID 27843625, PMID 28332888, PMID 29304768, PMID 31264912, PMID 34907980, PMID 36607735
2008 (1), 2009 (1), P30CA015704 (1), P30CA060553 (1), R01CA111187 (1), R01CA125069 (1), R01CA157469 (1), R21CA126450 (1), U01CA121947 (1)