12 completed, 4 unknown, 1 not yet recruiting, 1 recruiting. 11 Phase 3, 7 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 9, Suspended 1, Unknown 1 |
| Phase 2 | 7 | Completed 3, Unknown 3, Recruiting 1 |
| Not applicable | 1 | Not yet recruiting 1 |
Follow CMF regimen: new trials by email Literature Review of CMF regimen trials Research Report on CMF regimen
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Cyclophosphamide, Methotrexate, Fluorouracil (CMF) for People With Breast Cancer CMF Regimen, Paclitaxel - Adenocarcinoma of the Breast, Breast Cancer | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 76 | 2026-08-11 | 2026-08-17 |
| Early Supplementation for Cow's Milk Allergy Prevention Cow's milk formula [CMF], Amino-acid formula [AAF], Donor human milk [DHM] - Food Allergy, Cow's Milk Allergy | Not applicable | Not yet recruiting | Medical University of Warsaw | 1000 | 2025-07-01 | 2025-07-17 |
| Combination Chemotherapy With Trastuzumab in Treating Women With Metastatic Breast Cancer trastuzumab, CMF regimen, cyclophosphamide - Breast Cancer | Phase 2 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 90 | 2002-02-01 | 2024-03-08 |
| Combination Chemotherapy in Treating Women With Resected Breast Cancer CMF regimen, cyclophosphamide, docetaxel - Breast Cancer | Phase 2 | Unknown | Institute of Cancer Research, United Kingdom | 2001-02-01 | 2009-02-09 | |
| Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Chemotherapy Alone in Treating Women With Stage IV Breast Cancer filgrastim, CMF regimen, carboplatin - Breast Cancer | Phase 2 | Unknown | Herbert Irving Comprehensive Cancer Center | 2000-01-01 | 2014-01-06 | |
| Chemotherapy Followed by Surgery in Treating Women With Stage II or Stage III Breast Cancer filgrastim, CMF regimen, docetaxel - Breast Cancer | Phase 2 | Completed | Case Comprehensive Cancer Center | 39 | 1999-02-01 | 2013-01-28 |
| Standard Chemotherapy Compared With High-Dose Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Women With Advanced or Inflammatory Breast Cancer CMF regimen, cyclophosphamide, fluorouracil - Breast Cancer | Phase 3 | Unknown | Scottish Cancer Therapy Network | 300 | 1998-11-01 | 2013-11-06 |
| S9716: Combination Chemotherapy in Treating Patients With Merkel Cell Cancer CMF regimen, cyclophosphamide, fluorouracil - Neuroendocrine Carcinoma of the Skin | Phase 2 | Completed | SWOG Cancer Research Network | 80 | 1998-10-01 | 2012-10-08 |
| Adjuvant Chemotherapy Plus Radiation Therapy in Treating Women With Early-Stage Breast Cancer CMF regimen, cyclophosphamide, doxorubicin hydrochloride - Breast Cancer | Phase 3 | Completed | University Hospital Birmingham | 2250 | 1998-07-01 | 2013-12-19 |
| Combination Chemotherapy Following Surgery in Treating Women With Early Stage Breast Cancer CMF regimen, cyclophosphamide, epirubicin hydrochloride - Breast Cancer | Phase 3 | Completed | Scottish Cancer Therapy Network | 1000 | 1996-10-01 | 2013-11-06 |
| Chemotherapy Plus Surgery in Treating Women With Breast Cancer CMF regimen, cyclophosphamide, doxorubicin hydrochloride - Breast Cancer | Phase 3 | Completed | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 450 | 1996-10-01 | 2013-09-17 |
| High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Combination Chemotherapy in Treating Women With High-Risk Breast Cancer filgrastim, CMF regimen, cyclophosphamide - Breast Cancer | Phase 3 | Completed | ETOP IBCSG Partners Foundation | 344 | 1996-06-01 | 2013-04-04 |
| Combination Chemotherapy With or Without Epirubicin in Treating Women With Stage I or Stage II Breast Cancer CMF regimen, cyclophosphamide, epirubicin hydrochloride - Breast Cancer | Phase 3 | Completed | University Hospital Birmingham | 2000 | 1996-03-01 | 2013-12-19 |
| Standard Chemotherapy Compared With High-Dose Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer filgrastim, CMF regimen, cyclophosphamide - Breast Cancer | Phase 3 | Completed | Scottish Cancer Therapy Network | 600 | 1995-11-01 | 2013-11-06 |
| Combination Chemotherapy in Treating Women With Stage III Breast Cancer CAF regimen, CMF regimen, cyclophosphamide - Breast Cancer | Phase 3 | Suspended | Grupo Oncologico Cooperativo del Sur | 1995-10-01 | 2013-08-02 | |
| Tamoxifen in Treating Women With High-Risk Breast Cancer CMF regimen, cyclophosphamide, doxorubicin hydrochloride - Breast Cancer | Phase 3 | Completed | NCIC Clinical Trials Group | 672 | 1993-07-20 | 2020-04-01 |
| Tamoxifen, Ovarian Ablation, and/or Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA Breast Cancer CMF regimen, cyclophosphamide, doxorubicin hydrochloride - Breast Cancer | Phase 3 | Completed | Institute of Cancer Research, United Kingdom | 6000 | 1993-06-01 | 2013-08-02 |
| Tamoxifen Following Combination Chemotherapy in Treating Women With Operable Invasive Breast Cancer CMF regimen, cyclophosphamide, fluorouracil - Breast Cancer | Phase 3 | Completed | Scottish Cancer Therapy Network | 2000 | 1993-03-01 | 2013-11-06 |
| Combination Chemotherapy Compared With Mitoxantrone in Treating Older Patients With Advanced Breast Cancer CMF regimen, cyclophosphamide, fluorouracil - Breast Cancer | Phase 2 | Unknown | Leiden University Medical Center | 1992-07-01 | 2013-12-18 |
Breast Neoplasms (17) · Carcinoma, Merkel Cell (1) · Food Hypersensitivity (1) · Inflammatory Breast Neoplasms (1) · Milk Hypersensitivity (1) · Triple Negative Breast Neoplasms (1)
Scottish Cancer Therapy Network (4) · Institute of Cancer Research, United Kingdom (2) · University Hospital Birmingham (2) · Case Comprehensive Cancer Center (1) · ETOP IBCSG Partners Foundation (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano (1) · Grupo Oncologico Cooperativo del Sur (1) · Herbert Irving Comprehensive Cancer Center (1) · Leiden University Medical Center (1) · Medical University of Warsaw (1) · Memorial Sloan Kettering Cancer Center (1) · NCIC Clinical Trials Group (1) · SWOG Cancer Research Network (1)
United Kingdom (9) · United States (4) · Poland (3) · Belgium (2) · Netherlands (2) · Argentina (1) · Australia (1) · Austria (1) · Canada (1) · Czechia (1) · Denmark (1) · Egypt (1) · Estonia (1) · France (1) · Germany (1)
Helena Earl, MBBS, PhD, FRCP (2) · Andrea Horvath, Assoc Prof, MD (1) · Bernardo A. Leone, MD (1) · Brenda W. Cooper, MD (1) · Chris Twelves, MD, BMedSci, FRCP (1) · David Cameron (1) · Gianni Bonadonna, MD (1) · Hanna Szajewska, Prof, MD (1) · Indy Fernando, MD (1) · Jane Banerji (1) · John R. Yarnold, MD, FRCR (1) · Linda T. Vahdat, MD (1) · Marianne A. Nooij, MD (1) · Pamela Drullinsky, MD (1)
PMID 10076722, PMID 10458221, PMID 16421418, PMID 17405995, PMID 17405996, PMID 18768436, PMID 18797468, PMID 19332727, PMID 19468030, PMID 24915873, PMID 25897014, PMID 26852132, PMID 28324265, PMID 29179731, PMID 31785830, PMID 37012180, PMID 40764079, PMID 9816037
P30CA043703 (1), U10CA032102 (1)