9 completed, 3 terminated, 2 recruiting, 2 unknown. 10 Not applicable, 4 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 5, Recruiting 2, Suspended 1, Terminated 1, Unknown 1 |
| Phase 1 | 4 | Completed 2, Terminated 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 2, Not yet recruiting 1, Terminated 1 |
Follow Wheat Hypersensitivity: new trials by email Literature Review of Wheat Hypersensitivity trials Research Report on Wheat Hypersensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Safety, Efficacy, Pharmacokinetic and Pharmacodynamic Characteristics of LP-003 Injection in Participants With Wheat Allergy LP-003 Injection - Food Allergy, Wheat Hypersensitivity | Phase 2 | Not yet recruiting | Longbio Pharma (Suzhou) Co., Ltd. | 12 | 2026-09-04 | 2026-09-11 |
| A Phase 1 Study of Cizutamig in IgE Mediated Diseases Cizutamig - IgE-Mediated Hypersensitivity, IgE Mediated Food Allergy | Phase 1 | Withdrawn | Candid Therapeutics | 2026-04-01 | 2026-07-22 | |
| Human Breast Milk's Role in Food Allergy Development Open Ended Oral Food Challenge, Early Introduction - Food Allergy in Infants, Food Allergen Sensitisation | Withdrawn | The University of Texas Medical Branch, Galveston | 2024-03-08 | 2026-02-24 | ||
| Randomized Controlled Trial for Wheat Oral Immunotherapy Wheat-containing food - Allergy;Food, Wheat Allergy | Not applicable | Recruiting | Chinese University of Hong Kong | 72 | 2023-11-01 | 2024-02-08 |
| Comparison Efficacy Between Two Different Frequency of Maintenance Dose Oral Immunotherapy Wheat (Four times per week) - Wheat Hypersensitivity, Immunotherapy | Not applicable | Recruiting | Mahidol University | 64 | 2023-07-01 | 2025-05-09 |
| Wheat Bread Study: Comparison of the Tolerance of Different Wheat Breads Wheat bread - Non-celiac Gluten Sensitivity, Wheat Hypersensitivity | Not applicable | Unknown | University of Hohenheim | 64 | 2023-04-19 | 2024-05-17 |
| Open-label Extension Study of ADP101 ADP101 - Food Allergy | Phase 1 / Phase 2 | Terminated | Alladapt Immunotherapeutics, Inc. | 45 | 2022-03-14 | 2024-03-26 |
| ADP101 for Oral Immunotherapy in Food-Allergic Children and Adults Low dose ADP101, High dose ADP101, Pooled Placebo - Food Allergy | Phase 1 / Phase 2 | Completed | Alladapt Immunotherapeutics, Inc. | 73 | 2021-04-20 | 2024-05-16 |
| Luminex-based Assay to Identify Major IgE-binding Episode Among IgE-mediated Wheat-allergic Patient Blood drawing - Wheat Allergy | Completed | Mahidol University | 100 | 2019-09-13 | 2023-05-06 | |
| Outcome of Specific IgE Level in Children With IgE-mediated Wheat Allergy After Stop Using Wheat Containing Skin Care wheat containing skin care products - Wheat Allergy, Children | Not applicable | Terminated | Mahidol University | 7 | 2019-07-01 | 2022-04-08 |
| Specific Oral Tolerance Induction (SOTI) to Children With IgE-mediated Wheat Allergy Wheat spaghetti - Wheat Allergy | Unknown | Athens General Children's Hospital "Pan. & Aglaia Kyriakou" | 15 | 2018-01-08 | 2024-07-30 | |
| Food Challenge With Barley Starch as Active Comparator Barley starch, Maize starch - Allergy;Food, Allergy Wheat | Not applicable | Suspended | Lyckeby Starch AB | 40 | 2017-10-13 | 2019-03-05 |
| Changes in Intestinal Permeability 4 Hours After Gluten Challenge Gluten, Placebo - Celiac Disease, Wheat Hypersensitivity | Not applicable | Completed | Mayo Clinic | 60 | 2017-10-10 | 2019-06-07 |
| Major Allergen in Wheat Anaphylaxis in Thai Population immunoblot - Wheat Allergy, Anaphylaxis Food | Not applicable | Completed | Mahidol University | 36 | 2017-04-05 | 2018-04-04 |
| Self-reported Non-celiac Wheat Sensitivity (NCWS) in Patients Undergoing Digestive Endoscopy Questionnaire - Non-celiac Wheat Sensitivity | Completed | University of Palermo | 500 | 2017-01-01 | 2020-01-18 | |
| Evaluation of Potential Allergenicity of New Wheat Varieties Food Allergy, Wheat Allergy | Terminated | University of Colorado, Denver | 5 | 2014-11-01 | 2018-05-21 | |
| Oral Immunotherapy for Wheat Allergy Wheat OIT - Wheat Allergy | Phase 1 / Phase 2 | Completed | Hugh A Sampson, MD | 46 | 2013-10-01 | 2020-08-14 |
| The Natural History of Wheat Hypersensitivity in Thai Children oral wheat challenge - Wheat Allergy, Child | Not applicable | Completed | Mahidol University | 43 | 2012-11-01 | 2015-04-09 |
| Oral Desensitization to Wheat in School Aged Children Wheat oral immunotherapy - Wheat Allergy | Not applicable | Completed | Helsinki University Central Hospital | 100 | 2009-08-01 | 2015-03-20 |
| Accuracy Of Skin Prick Test Using In-house Wheat Extract For The Diagnosis Of IgE-mediated Wheat Allergy: A Pilot Study Commercial extract and in-house wheat extract - Wheat Allergy | Not applicable | Completed | Mahidol University | 30 | 2009-06-01 | 2013-02-28 |
Food Hypersensitivity (10) · Egg Hypersensitivity (4) · Milk Hypersensitivity (4) · Hypersensitivity, Immediate (3) · Nut Hypersensitivity (3) · Peanut Hypersensitivity (3) · Celiac Disease (2) · Hypersensitivity (2) · Immune System Diseases (2) · Shellfish Hypersensitivity (2) · Asthma (1) · Breast Feeding (1) · Breast Milk Expression (1) · Dermatitis, Atopic (1)
Hypersensitivity (18) · Immune System Diseases (18) · Hypersensitivity, Immediate (17) · Food Hypersensitivity (10) · Nut and Peanut Hypersensitivity (3) · Digestive System Diseases (2) · Gastrointestinal Diseases (2) · Intestinal Diseases (2) · Malabsorption Syndromes (2) · Metabolic Diseases (2) · Nutritional and Metabolic Diseases (2) · Behavior (1) · Bronchial Diseases (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Dermatitis (1)
Blood Specimen Collection (1) · Flour (1) · Glutens (1) · Starch (1) · Surveys and Questionnaires (1)
Mahidol University (6) · Alladapt Immunotherapeutics, Inc. (2) · Athens General Children's Hospital "Pan. & Aglaia Kyriakou" (1) · Candid Therapeutics (1) · Chinese University of Hong Kong (1) · Helsinki University Central Hospital (1) · Hugh A Sampson, MD (1) · Longbio Pharma (Suzhou) Co., Ltd. (1) · Lyckeby Starch AB (1) · Mayo Clinic (1) · The University of Texas Medical Branch, Galveston (1) · University of Colorado, Denver (1) · University of Hohenheim (1) · University of Palermo (1)
Thailand (6) · United States (5) · Finland (2) · Australia (1) · China (1) · Germany (1) · Greece (1) · Hong Kong (1) · Italy (1)
Punchama Pacharn, MD (4) · Mei-Lun Wang, MD (2) · Antonio Carroccio, PHD (1) · David Fleischer, MD (1) · Hugh A Sampson, MD (1) · Joseph A. Murray, M.D. (1) · Kai Guan (1) · Marita Paassilta, MD, Docent (1) · Nikolaos Kitsioulis, MD (1) · Nikolaos Papadopoulos, MD, PhD (1) · Ting Fan Leung, MBChB, MD (1)
PMID 12655262, PMID 22825366, PMID 24216570, PMID 24275240, PMID 24533607, PMID 24759554, PMID 25430806, PMID 25601168, PMID 25625764, PMID 25694210, PMID 30528770, PMID 34334709, PMID 34797778, PMID 7910231
UL1TR001082 (1)