8 completed, 1 recruiting, 1 terminated, 1 unknown. 11 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 11 | Completed 8, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Migraine without Aura: new trials by email Literature Review of Migraine without Aura trials Research Report on Migraine without Aura
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of EVO756 in Adults With Migraine EVO756, Dose 1, EVO756, Dose 2, Placebo - Migraine | Phase 2 | Recruiting | Evommune, Inc. | 330 | 2026-07-29 | 2026-11-13 |
| Can DFN-15 Terminate Migraine With Allodynia? DFN-15, Placebo - Migraine With Aura, Migraine Without Aura | Phase 2 | Completed | Hartford Hospital | 51 | 2018-05-09 | 2019-04-16 |
| Low-Dose Naltrexone and Acetaminophen Combination and Its Components in the Acute Treatment of Migraine Naltrexone and Acetaminophen, Naltrexone and Acetaminophen-High Dose, Naltrexone Alone (regular dose) - Migraine With or Without Aura | Phase 2 | Completed | Allodynic Therapeutics, Inc | 92 | 2017-02-18 | 2021-04-14 |
| Botox Injection in Treatment of Chronic Migraine Botulinum Toxin Type A - Migraine Disorders | Phase 1 / Phase 2 | Completed | Norwegian University of Science and Technology | 10 | 2015-02-01 | 2016-05-23 |
| Study of the Safety and Effectiveness of NXN-188 for the Treatment of Migraine Headache Without Aura NXN-188, Placebo - Migraine Without Aura | Phase 2 | Completed | NeurAxon Inc. | 195 | 2009-07-01 | 2014-07-23 |
| Candesartan Versus Propranolol for Migraine Prevention Candesartan, propranolol, placebo - Migraine Without Aura, Migraine With Aura | Phase 2 / Phase 3 | Completed | Norwegian University of Science and Technology | 72 | 2009-04-01 | 2013-12-24 |
| A Study of a Melatonin Receptor Agonist to Prevent Migraine Ramelteon, Placebo - Migraine, Migraine With Aura | Phase 2 | Terminated | Swedish Medical Center | 18 | 2008-04-01 | 2012-08-23 |
| Dose Ranging Study of the Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache Tonabersat, Placebo - Migraine Without Aura, Migraine With Aura | Phase 2 | Completed | Minster Research Ltd | 542 | 2007-10-01 | 2009-03-31 |
| Efficacy and Safety Clinical Trial of Intranasal AST-726 for the Prevention of Migraine AST-726 Low dose, AST-726 High dose, AST-726 Placebo - Migraine, Migraine Headache | Phase 2 | Unknown | Ariston Pharmaceuticals, Inc. | 198 | 2007-05-01 | 2008-02-08 |
| Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache Tonabersat, Placebo - Migraine Without Aura, Migraine With Aura | Phase 2 | Completed | Minster Research Ltd | 124 | 2006-04-01 | 2009-08-31 |
| Study to Evaluate the Efficacy and Safety of Dronabinol Metered Dose Inhaler (MDI) in Acute Treatment of Migraine Headache Dronabinol MDI - Migraine With Aura, Migraine Without Aura | Phase 2 | Completed | Solvay Pharmaceuticals | 2005-09-01 | 2015-01-16 |
Migraine with Aura (10) · Migraine Disorders (7) · Headache Disorders (2) · Headache (1) · Hyperalgesia (1)
Brain Diseases (11) · Central Nervous System Diseases (11) · Headache Disorders, Primary (11) · Nervous System Diseases (11) · Headache Disorders (9) · Migraine Disorders (4) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Pain (1) · Sensation Disorders (1) · Somatosensory Disorders (1)
tonabersat (2) · Acetaminophen (1) · Botulinum Toxins, Type A (1) · Celecoxib (1) · Naltrexone (1) · Propranolol (1) · candesartan (1) · ramelteon (1)
Minster Research Ltd (2) · Norwegian University of Science and Technology (2) · Allodynic Therapeutics, Inc (1) · Ariston Pharmaceuticals, Inc. (1) · Evommune, Inc. (1) · Hartford Hospital (1) · NeurAxon Inc. (1) · Solvay Pharmaceuticals (1) · Swedish Medical Center (1)
United States (6) · Norway (2) · United Kingdom (2) · Australia (1) · Canada (1) · Denmark (1) · Finland (1) · Hungary (1) · Netherlands (1) · New Zealand (1) · South Africa (1)
Annette C Toledano, M.D. (1) · Erling A Tronvik, PhD, MD (1) · Guy Boudreau, MD (1) · Lars J Stovner, Ph.D. (1) · Peter Goadsby, MD (1) · Richard Lipton, MD (1) · Sheena K Aurora, MD (1) · W. M. Mulleners (1)
PMID 11112243, PMID 16135345, PMID 17175134, PMID 18662331, PMID 19222510, PMID 19453963, PMID 20548058, PMID 22520687, PMID 24335848, PMID 25744676, PMID 26603732, PMID 27154997, PMID 28322750, PMID 29310498
2008 (1), 2014 (1)