5 completed, 4 unknown, 3 not yet recruiting, 1 enrolling by invitation. 6 Phase 4, 3 Phase 2, 3 Phase 3, 1 Early Phase 1, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 3, Not yet recruiting 3 |
| Phase 2 | 3 | Unknown 2, Completed 1 |
| Phase 3 | 3 | Unknown 2, Enrolling by invitation 1 |
| Early Phase 1 | 1 | Unknown 1 |
| Not applicable | 1 | Unknown 1 |
Follow Methylprednisolone: new trials by email Literature Review of Methylprednisolone trials Research Report on Methylprednisolone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Methylprednisolone After Flow-Diverter Stent Implantation in Unruptured Intracranial Aneurysms Methylprednisolone (Injectable Form), Placebo Injection - Unruptured Intracranial Aneurysms, Cerebrovascular Event | Phase 4 | Not yet recruiting | Duan Chuanzhi | 864 | 2026-11-30 | 2026-10-26 |
| Neuroendoscopic Hematoma Evacuation Combined With Methylprednisolone Sodium Succinate in the Treatment of Basal Ganglia Intracerebral Hemorrhage at the Early Stage Simple neuroendoscopic hematoma evacuation, Neuroendoscopic hematoma evacuation combined with sodium methylprednisolone succinate - Stroke, Intracerebral Hemorrhage Basal Ganglia | Phase 4 | Not yet recruiting | Yong Jiang | 100 | 2025-05-01 | 2025-04-13 |
| Neuroendoscopic Hematoma Evacuation Combined With Methylprednisolone Sodium Succinate in the Treatment of Lobar Intracerebral Hemorrhage at the Early Stage. Simple neuroendoscopic hematoma evacuation, Neuroendoscopic hematoma evacuation combined with sodium methylprednisolone succinate - Stroke, Intracerebral Hemorrhage Lobar | Phase 4 | Not yet recruiting | Yong Jiang | 396 | 2025-05-01 | 2025-04-13 |
| Comparing Methylprednisolone And Hyaluronic Acid To Reduce Wisdom Tooth Surgery Complications Methyl Prednisolone (MP), Hyaluronic Acid (HA) - Wisdom Tooth Removal, Post Operative Complications | Phase 3 | Enrolling by invitation | Sana'a University | 40 | 2024-06-27 | 2026-04-30 |
| PreOperative Methylprednisolone on Thoracic Endovascular Repair for Reducing Post-implantation Syndrome (POMTEVAR) methylprednisolone, physiological saline - Methylprednisolone, Thoracic Endovascular Repair | Not applicable | Unknown | Guangdong Provincial People's Hospital | 158 | 2022-05-01 | 2022-04-27 |
| Effect of Intravenous Methylprednisolone and Intravenous Erythropoietin in Toxic Optic Neuropathies: Randomized Clinical Trial. Recombinant human erythropoietin 4,000 UI and 2,000 UI, Methylprednisolone succinate 500 mg - Toxic Optic Neuropathy, Treatment | Phase 2 / Phase 3 | Unknown | Asociación para Evitar la Ceguera en México | 18 | 2022-04-05 | 2023-02-28 |
| Glucocorticoids for Post-operative Patients With Acute Type A Aortic Dissection (The GLAD Trial) Methylprednisolone Injection - Methylprednisolone, Glucocorticoid | Phase 4 | Completed | Shanghai Zhongshan Hospital | 212 | 2022-02-07 | 2023-12-26 |
| Retrobulbar Methylprednisolone as Adjunctive Treatment in Optic Neuritis Trial Methylprednisolone Acetate 40 MG/ML [Depo-Medrol], Placebo Comparator: Standard treatment + placebo - Optic Neuritis, Treatment | Phase 2 / Phase 3 | Unknown | Asociación para Evitar la Ceguera en México | 50 | 2021-06-15 | 2021-06-28 |
| Corticosteroid Effects on Asymptomatic Gadolinium-enhancing Lesions in Multiple Sclerosis Methylprednisolone succinate, Normal saline - Multiple Sclerosis, Relapsing-Remitting, Magnetic Resonance Imaging | Phase 2 | Completed | Mazandaran University of Medical Sciences | 102 | 2021-05-22 | 2025-07-15 |
| Investigation of Hospitalisation Times and Mortality According to Drug Dose in Patients Given Systemic Methylprednisolone With a Pre-diagnosis of Covid-19 Pneumonia; Retrospective Study methylprednisolone - COVID-19, Methylprednisolone | Completed | Bursa Yuksek Ihtisas Training and Research Hospital | 300 | 2021-03-01 | 2021-04-19 | |
| Histopathological, Biochemical And Electrophysiological Evaluation Of Single Or Combined Use Of Diode Laser/Steroid Treatment On Facial Nerve Injury Methyprednisolon and low level laser theraphy - Nerve Injury, Laser Therapy | Early Phase 1 | Unknown | Recep Tayyip Erdogan University | 35 | 2021-01-01 | 2024-01-03 |
| Effects of Methylprednisolone on Immunological Function and Postoperative Pain Methylprednisolone 1 mg•kg-1, isotonic saline 1mg•kg-1 - Methylprednisolone, Immunological Function | Phase 4 | Completed | Shengjing Hospital | 112 | 2015-07-01 | 2020-12-10 |
| The Effect of a Preoperative Single-dose Methylprednisolone on the Postoperative Rehabilitation After Abdominal Hysterectomy Methylprednisolone 125mg, Sodium Chloride 2 ml - Hysterectomy, Methylprednisolone | Phase 4 | Completed | Holbaek Sygehus | 55 | 2009-08-01 | 2011-10-13 |
Pain, Postoperative (2) · Stroke (2) · Aortic Dissection (1) · COVID-19 (1) · Facial Nerve Injuries (1) · Hemorrhagic Stroke (1) · Intracranial Aneurysm (1) · Multiple Sclerosis (1) · Multiple Sclerosis, Relapsing-Remitting (1) · Optic Neuritis (1) · Pneumonia (1) · Toxic Optic Neuropathy (1)
Nervous System Diseases (7) · Cardiovascular Diseases (4) · Vascular Diseases (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Cerebrovascular Disorders (3) · Cranial Nerve Diseases (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Aneurysm (2) · Cranial Nerve Injuries (2) · Craniocerebral Trauma (2) · Eye Diseases (2) · Neurologic Manifestations (2) · Optic Nerve Diseases (2)
Methylprednisolone Hemisuccinate (6) · Methylprednisolone (5) · Control Groups (1) · Exercise (1) · Hyaluronic Acid (1) · Methods (1) · Methylprednisolone Acetate (1) · Saline Solution (1) · Sodium Chloride (1)
Asociación para Evitar la Ceguera en México (2) · Yong Jiang (2) · Bursa Yuksek Ihtisas Training and Research Hospital (1) · Duan Chuanzhi (1) · Guangdong Provincial People's Hospital (1) · Holbaek Sygehus (1) · Mazandaran University of Medical Sciences (1) · Recep Tayyip Erdogan University (1) · Sana'a University (1) · Shanghai Zhongshan Hospital (1) · Shengjing Hospital (1)
China (5) · Mexico (2) · Turkey (Türkiye) (2) · Denmark (1) · Iran (1) · Yemen (1)
Amal Y Al-Eryani (1) · Chuanzhi Duan (1) · Jianfang Luo, MD (1) · Junchao Zhu, doctor (1) · Karen Flores-Guevara, MD (1) · Octavio Turcio-Aceves, MD (1) · Seyed Mohammad Baghbanian, Dr. (1) · Zhe Luo, MD, PhD (1)