7 active not recruiting, 1 recruiting, 1 terminated. 4 Phase 1, 3 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Active not recruiting 4 |
| Phase 2 | 3 | Active not recruiting 2, Recruiting 1 |
| Phase 3 | 2 | Active not recruiting 1, Terminated 1 |
Follow Metastatic Lung Small Cell Carcinoma: new trials by email Literature Review of Metastatic Lung Small Cell Carcinoma trials Research Report on Metastatic Lung Small Cell Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer Atezolizumab, Temozolomide - Extensive Stage Lung Small Cell Carcinoma, Metastatic Lung Small Cell Carcinoma | Phase 2 | Recruiting | Dwight Owen | 56 | 2022-01-26 | 2026-04-08 |
| Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV Biospecimen Collection, Cabozantinib S-malate, Computed Tomography - Advanced Differentiated Thyroid Gland Carcinoma, Advanced Head and Neck Carcinoma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 8 | 2021-11-22 | 2026-05-28 |
| Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer Biopsy Procedure, Biospecimen Collection, Computed Tomography - Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Solid Neoplasm | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 29 | 2021-10-20 | 2026-09-10 |
| Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Lung Non-Small Cell Carcinoma | Phase 3 | Terminated | NRG Oncology | 19 | 2021-08-05 | 2026-05-20 |
| Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability Biospecimen Collection, Magnetic Resonance Imaging, Memantine Hydrochloride - Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain | Phase 3 | Active not recruiting | NRG Oncology | 152 | 2021-06-08 | 2026-09-14 |
| Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis Questionnaire Administration, Stereotactic Radiosurgery - Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 55 | 2020-08-28 | 2026-09-14 |
| Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors Berzosertib, Quality-of-Life Assessment, Therapeutic Conventional Surgery - Metastatic Lung Neuroendocrine Neoplasm, Metastatic Lung Non-Small Cell Carcinoma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 15 | 2017-05-22 | 2026-10-14 |
| A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors 18F-Fluoromisonidazole, Cediranib Maleate, Laboratory Biomarker Analysis - Advanced Malignant Solid Neoplasm, Metastatic Lung Non-Small Cell Carcinoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 122 | 2016-08-31 | 2026-09-25 |
| M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery Berzosertib, Biopsy Specimen, Biospecimen Collection - Metastatic Colorectal Carcinoma, Metastatic Lung Small Cell Carcinoma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 66 | 2016-07-22 | 2026-09-25 |
Small Cell Lung Carcinoma (9) · Lung Neoplasms (8) · Brain Neoplasms (4) · Carcinoma, Non-Small-Cell Lung (4) · Neoplasm Metastasis (4) · Breast Neoplasms (2) · Carcinoma, Renal Cell (2) · Melanoma (2) · Pancreatic Neoplasms (2) · Triple Negative Breast Neoplasms (2) · Carcinoma, Hepatocellular (1) · Carcinoma, Medullary (1) · Carcinoma, Neuroendocrine (1) · Carcinoma, Transitional Cell (1) · Colorectal Neoplasms (1)
Bronchial Neoplasms (9) · Carcinoma, Bronchogenic (9) · Lung Diseases (9) · Neoplasms (9) · Neoplasms by Site (9) · Respiratory Tract Diseases (9) · Respiratory Tract Neoplasms (9) · Thoracic Neoplasms (9) · Brain Diseases (4) · Central Nervous System Diseases (4) · Central Nervous System Neoplasms (4) · Digestive System Diseases (4) · Digestive System Neoplasms (4) · Neoplastic Processes (4) · Nervous System Diseases (4)
Magnetic Resonance Spectroscopy (5) · Specimen Handling (5) · Radiosurgery (3) · Irinotecan (2) · Memantine (2) · berzosertib (2) · BAY 1895344 (1) · Biopsy (1) · Mental Status and Dementia Tests (1) · Nivolumab (1) · Temozolomide (1) · Topotecan (1) · atezolizumab (1) · cabozantinib (1) · cediranib (1)
National Cancer Institute (NCI) (5) · NRG Oncology (2) · Dwight Owen (1) · M.D. Anderson Cancer Center (1)
United States (9) · Canada (3) · Hong Kong (1)
Vinai Gondi (2) · Dwight Owen (1) · Haiying Cheng (1) · Jing Li (1) · Joseph W Kim (1) · Liza C Villaruz (1) · Pranshu Mohindra (1) · Thatcher Heumann (1)
UM1CA186689 (3), UM1CA186644 (2), UM1CA186690 (2), U10CA180868 (1), UG1CA189867 (1), UM1CA186686 (1), UM1CA186691 (1), UM1CA186704 (1), UM1CA186717 (1)