5 completed, 2 withdrawn, 1 recruiting, 1 unknown. 9 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 5, Withdrawn 2, Recruiting 1, Unknown 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Melasma: new trials by email Literature Review of Melasma trials Research Report on Melasma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral Metformin for Treating Melasma in Latin American Women Metformin - Melasma | Phase 1 / Phase 2 | Recruiting | University of Puerto Rico | 30 | 2025-02-20 | 2025-02-25 |
| Oral Isotretinoin in Melasma a Randomized Controlled Trial Isotretinoin, Triple combination formula - Melasma | Phase 1 | Unknown | Zagazig University | 40 | 2023-03-01 | 2024-01-11 |
| Comparison of Azelaic Acid 20 % Cream Versus Hydroquinone 4% Cream as an Adjuvant to Oral Tranexamic Acid in Melasma Group A 4 % Hydroquinone Cream Topically and Oral Tranexamic Acid, Group B Azelaic Acid 20 % Cream for 6 months - Melasma | Phase 1 | Completed | Combined Military Hospital Abbottabad | 50 | 2022-11-01 | 2023-06-02 |
| Comparison of Intralesional Tranexamic Acid and Platelets Rich Plasma in the Treatment of Melasma Tranexamic acid, Platelets rich plasma - Melasma | Phase 1 | Completed | Combined Military Hospital Abbottabad | 60 | 2022-11-01 | 2023-06-01 |
| Green Banana Peel Extract for Melasma Treatment SPF 30 sunscreen plus pharmaceutical formulation without green banana peel extract, SPF 30 sunscreen and pharmaceutical formulation containing green banana peel extract - Melasma | Phase 1 | Completed | Universidade do Vale do Sapucai | 74 | 2021-06-30 | 2021-09-02 |
| Comparison of Chemical Peeling Agent With Transamine for Treatment of Melasma Glycolic Acid 70%, Tranexamic acid injection - Melasma | Phase 1 | Completed | Combined Military Hospital Abbottabad | 54 | 2021-06-01 | 2022-05-05 |
| Tri-split Face Study of Skin Resurfacing Modalities for the Treatment of Melasma 22% TCA peel, CO2 laser, Qs-NdYag laser - Melasma | Phase 1 | Withdrawn | SUZAN OBAGI | 2020-12-01 | 2020-03-25 | |
| Spironolactone for the Treatment of Melasma Spironolactone 50Mg Tablet, Spironolactone 100Mg Tablet, Spironolactone 200Mg - Melasma | Phase 1 | Withdrawn | Medical University of South Carolina | 2020-03-05 | 2024-09-04 | |
| Comparative Study of mMASI Before and After Hyperthyroid Therapy in Hyperthyroid Subjects With Melasma Thiamazol - Melasma, Hyperthyroidism | Phase 1 | Completed | Dr.dr.Irma Bernadette, SpKK (K) | 23 | 2019-08-01 | 2020-05-06 |
Melanosis (9) · Hyperthyroidism (1)
Hyperpigmentation (9) · Pigmentation Disorders (9) · Skin Diseases (9) · Skin and Connective Tissue Diseases (9) · Endocrine System Diseases (1) · Thyroid Diseases (1)
Tranexamic Acid (3) · Canrenoic Acid (1) · Drug Compounding (1) · Isotretinoin (1) · Lasers, Gas (1) · Metformin (1) · Methimazole (1) · Spironolactone (1) · Tablets (1) · Tranylcypromine (1)
Combined Military Hospital Abbottabad (3) · Dr.dr.Irma Bernadette, SpKK (K) (1) · Medical University of South Carolina (1) · SUZAN OBAGI (1) · Universidade do Vale do Sapucai (1) · University of Puerto Rico (1) · Zagazig University (1)
Pakistan (3) · Brazil (1) · Egypt (1) · Indonesia (1) · Puerto Rico (1) · United States (1)
Cristina Brau (1) · Dirk Elston, MD (1) · Irma B Sitohang, MD, PhD (1) · Naheed Khan (1) · Suzan Obagi, MD (1)