4 unknown, 3 completed, 2 withdrawn, 1 not yet recruiting. 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1 | Withdrawn 1 |
Follow Malignant Hyperthermia: new trials by email Literature Review of Malignant Hyperthermia trials Research Report on Malignant Hyperthermia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Prevalence of RYR1-related Disease Neuromuscular Disease, Malignant Hyperthermia | Not yet recruiting | King's College London | 2000 | 2025-02-01 | 2025-01-24 | |
| A Case Control Study of Patients With Diagnosis of Malignant Hyperthermia Malignant Hyperthermia | Withdrawn | Children's Hospital Medical Center, Cincinnati | 2023-05-01 | 2022-12-15 | ||
| Inadvertent Hypothermia or Hyperthermia in Pediatric Radiotherapy Practices Under Anesthesia radiotherapy under anesthesia - Hypothermia; Anesthesia, Hyperthermia, Anesthesia Related | Completed | Ankara City Hospital Bilkent | 152 | 2022-08-01 | 2022-10-13 | |
| Screening of Malignant Hyperthermia Susceptible Individuals Malignant Hyperthermia | Recruiting | Peking University Third Hospital | 50 | 2022-02-22 | 2022-06-02 | |
| Malignant Hyperthermia in Czech Republic: Description of the Biggest Slavonic Group of Patients Investigated for Risk of Malignant Hyperthermia Data analysis - Malignant Hyperthermia | Completed | Brno University Hospital | 286 | 2021-09-01 | 2022-04-15 | |
| Multisystem Features of Malignant Hyperthermia or Rhabdomyolysis Related to RYR1 Variants Immunological challenge - Malignant Hyperthermia, Rhabdomyolysis | Unknown | Radboud University Medical Center | 40 | 2020-08-19 | 2021-07-28 | |
| Population at Risk of Malignant Hyperthermia: Ambispective Cohort. In vitro contracture test (IVCT), In vitro test of hypermetabolism in B lymphocytes, Genetic test - Hyperthermia, Malignant | Unknown | Instituto de Investigación Hospital Universitario La Paz | 90 | 2020-02-26 | 2022-01-13 | |
| Gene Mutation Spectrum of Malignant Hyperthermia in China gene sequencing - Malignant Hyperthermia | Unknown | West China Hospital | 200 | 2019-01-15 | 2021-11-10 | |
| Spanish Registry of RYR1 and CACNA1S Polymorphisms Diagnostic of polymorphisms in malignant hyperthermia - Malignant Hyperthermia, Polymorphisms in Genes RYR1 and CACNAS1S | Unknown | Hospital Universitario La Fe | 5000 | 2018-12-05 | 2019-05-29 | |
| Malignant Hyperthermia Registry and Genetic Testing Whole exome sequencing - Malignant Hyperthermia | Terminated | Children's Hospital Medical Center, Cincinnati | 64 | 2015-08-18 | 2020-09-03 | |
| Effectiveness of Carbon Filters to Reduce the Anesthetic Gas Concentration in an Anesthetized Patient In-line Carbon filter (Vapor-Clean) - Malignant Hyperthermia | Not applicable | Withdrawn | Johns Hopkins University | 2012-07-01 | 2014-09-11 | |
| Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies Sepsis, Primary Myopathies | Completed | University Hospital, Basel, Switzerland | 22 | 2006-09-01 | 2021-11-29 |
Critical Illness (1) · Hyperthermia (1) · Hypothermia (1) · Minicore Myopathy with External Ophthalmoplegia (1) · Muscular Atrophy (1) · Muscular Diseases (1) · Myopathies, Nemaline (1) · Myopathies, Structural, Congenital (1) · Myopathy, Central Core (1) · Myotonia Congenita (1) · Neoplasms (1) · Neuromuscular Diseases (1) · Radiation Injuries (1) · Rhabdomyolysis (1)
Body Temperature Changes (12) · Intraoperative Complications (12) · Pathologic Processes (12) · Pathological Conditions, Signs and Symptoms (12) · Postoperative Complications (12) · Signs and Symptoms (12) · Hyperthermia (11) · Musculoskeletal Diseases (3) · Muscular Diseases (2) · Nervous System Diseases (2) · Wounds and Injuries (2) · Atrophy (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Disease Attributes (1) · Genetic Diseases, Inborn (1)
Base Sequence (1) · Exome Sequencing (1) · Genetic Testing (1)
Children's Hospital Medical Center, Cincinnati (2) · Ankara City Hospital Bilkent (1) · Brno University Hospital (1) · Hospital Universitario La Fe (1) · Instituto de Investigación Hospital Universitario La Paz (1) · Johns Hopkins University (1) · King's College London (1) · Peking University Third Hospital (1) · Radboud University Medical Center (1) · University Hospital, Basel, Switzerland (1) · West China Hospital (1)
China (2) · Spain (2) · United States (2) · Czechia (1) · Netherlands (1) · Switzerland (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Albert Urwyler, Professor MD (1) · Bin Liu, MD (1) · John McAuliffe, MD (1) · Petr Stourac, prof. MD., Ph.D. (1) · Robert S Greenberg, MD (1) · Yunxia Zuo, MD (1)
PMID 17714574, PMID 20649524, PMID 24758395, PMID 26506402, PMID 31559918, PMID 34414986, PMID 38763619, PMID 41913278