3 recruiting, 2 active not recruiting, 1 completed, 1 withdrawn. 7 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Recruiting 3, Active not recruiting 2, Completed 1, Withdrawn 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Malignant Brain Neoplasm: new trials by email Literature Review of Malignant Brain Neoplasm trials Research Report on Malignant Brain Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers Computed Tomography, Fludeoxyglucose F-18, Gallium Ga 68 FAPi-46 - Anal Carcinoma, Bladder Carcinoma | Phase 1 | Active not recruiting | Jonsson Comprehensive Cancer Center | 30 | 2025-08-01 | 2026-10-20 |
| Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors Advanced Magnetic Resonance Imaging, Brain Surgery, Electronic Health Record Review - Glioma, Malignant Brain Neoplasm | Phase 1 | Recruiting | Jonsson Comprehensive Cancer Center | 20 | 2024-12-05 | 2026-02-05 |
| Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer Etoposide, Fludarabine Phosphate, Hematopoietic Cell Transplantation - Anaplastic Ependymoma, Atypical Teratoid/Rhabdoid Tumor | Phase 1 | Withdrawn | M.D. Anderson Cancer Center | 2021-01-14 | 2024-10-26 | |
| CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children Cyclophosphamide, Fludarabine, IL13Ralpha2-specific Hinge-optimized 41BB-co-stimulatory CAR Truncated CD19-expressing Autologous T-Lymphocytes - Malignant Brain Neoplasm, Recurrent Malignant Brain Neoplasm | Phase 1 | Recruiting | City of Hope Medical Center | 18 | 2020-12-11 | 2026-10-15 |
| Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers Computed Tomography, Gallium Ga 68 FAPi-46, Positron Emission Tomography - Bladder Carcinoma, Cervical Carcinoma | Phase 1 | Active not recruiting | Jonsson Comprehensive Cancer Center | 26 | 2020-08-27 | 2026-11-06 |
| Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study Biospecimen Collection, Genetic Counseling, Genetic Testing - Breast Carcinoma, Digestive System Neoplasm | Phase 1 | Completed | Mayo Clinic | 230 | 2020-06-29 | 2023-07-24 |
| Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery Near-Infrared Fluorescence Imaging, Panitumumab, Panitumumab-IRDye800 - Malignant Brain Neoplasm, Malignant Glioma | Phase 1 / Phase 2 | Recruiting | Stanford University | 46 | 2018-05-16 | 2026-06-29 |
Brain Neoplasms (7) · Glioma (3) · Adrenal Gland Neoplasms (2) · Breast Neoplasms (2) · Carcinoma, Hepatocellular (2) · Carcinoma, Transitional Cell (2) · Cholangiocarcinoma (2) · Neoplasms, Unknown Primary (2) · Neuroendocrine Tumors (2) · Testicular Neoplasms (2) · Thyroid Neoplasms (2) · Urinary Bladder Neoplasms (2) · Uterine Cervical Neoplasms (2) · Anus Neoplasms (1) · Carcinoma, Medullary (1)
Brain Diseases (7) · Central Nervous System Diseases (7) · Neoplasms (7) · Neoplasms by Site (7) · Nervous System Diseases (7) · Nervous System Neoplasms (7) · Central Nervous System Neoplasms (6) · Neoplasms by Histologic Type (5) · Neoplasms, Germ Cell and Embryonal (5) · Neoplasms, Glandular and Epithelial (5) · Neoplasms, Nerve Tissue (5) · Neuroectodermal Tumors (5) · Digestive System Diseases (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3)
Magnetic Resonance Spectroscopy (3) · FAPI-46 (2) · Fluorodeoxyglucose F18 (2) · Antilymphocyte Serum (1) · Cyclophosphamide (1) · Etoposide (1) · Genetic Counseling (1) · Genetic Testing (1) · Hematopoietic Stem Cell Transplantation (1) · Melphalan (1) · Mycophenolic Acid (1) · Panitumumab (1) · Stem Cell Transplantation (1) · Tacrolimus (1) · Thiotepa (1)
Jonsson Comprehensive Cancer Center (3) · City of Hope Medical Center (1) · M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · Stanford University (1)
United States (6)
Jeremie Calais (2) · Kris M Mahadeo, MD (1) · Leo D Wang (1) · Lindsay Moore, MD (1) · Niloy J Samadder (1) · Robert M Prins (1)
P30CA016042 (1), P30CA033572 (1), P50CA211015 (1), R01CA190306 (1), R01CA267726 (1)