10 recruiting, 4 active not recruiting, 3 completed, 2 withdrawn. 7 Phase 1, 6 Not applicable, 5 Phase 2, 2 Early Phase 1.
Follow Malignant Brain Neoplasm: new trials by email Literature Review of Malignant Brain Neoplasm trials Research Report on Malignant Brain Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors Computed Tomography, Fluorodopa F 18, Positron Emission Tomography - Malignant Brain Neoplasm | Phase 2 | Recruiting | Mayo Clinic | 47 | 2026-03-24 | 2026-04-28 |
| Educational Tools for the Improvement of Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors Advance Care Planning, Educational Intervention, Electronic Health Record Review - Advanced Malignant Solid Neoplasm, Malignant Brain Neoplasm | Not applicable | Recruiting | Mayo Clinic | 50 | 2025-09-02 | 2026-07-08 |
| Advanced Magnetic Resonance Imaging for the Identification of Recurrent Brain Tumors and Radiation Necrosis Advanced Magnetic Resonance Imaging, Biospecimen Collection, Magnetic Resonance Imaging - Malignant Brain Neoplasm, Metastatic Malignant Neoplasm in the Brain | Not applicable | Recruiting | Jonsson Comprehensive Cancer Center | 42 | 2025-08-28 | 2026-01-15 |
| Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers Computed Tomography, Fludeoxyglucose F-18, Gallium Ga 68 FAPi-46 - Anal Carcinoma, Bladder Carcinoma | Phase 1 | Active not recruiting | Jonsson Comprehensive Cancer Center | 30 | 2025-08-01 | 2026-10-20 |
| Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases Biospecimen Collection, Exercise Intervention, Magnetic Resonance Imaging - Malignant Brain Neoplasm, Malignant Solid Neoplasm | Not applicable | Recruiting | Mayo Clinic | 147 | 2025-02-05 | 2026-06-10 |
| Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial Biospecimen Collection, Computed Tomography, Dexamethasone - Low Grade Glioma, Malignant Brain Glioma | Phase 2 | Recruiting | Emory University | 200 | 2025-01-09 | 2026-02-10 |
| Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors Advanced Magnetic Resonance Imaging, Brain Surgery, Electronic Health Record Review - Glioma, Malignant Brain Neoplasm | Phase 1 | Recruiting | Jonsson Comprehensive Cancer Center | 20 | 2024-12-05 | 2026-02-05 |
| Defining Musical Toxicity and Its Effect on Patient Well-being Non-Interventional Study - Breast Carcinoma, Esophageal Carcinoma | Withdrawn | Mayo Clinic | 2024-08-15 | 2025-06-04 | ||
| Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy Best Practice, Medical Device Usage and Evaluation, Metformin - Malignant Brain Neoplasm | Phase 2 | Active not recruiting | Mayo Clinic | 100 | 2024-05-31 | 2026-10-02 |
| Low Dose Versus Standard Dose Dexamethasone for Reduction of Swelling in Patients with Primary or Metastatic Brain Tumors Dexamethasone - Malignant Brain Neoplasm, Metastatic Malignant Neoplasm in the Brain | Phase 2 | Unknown | City of Hope Medical Center | 26 | 2022-04-09 | 2024-09-19 |
| Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors Medical Device Usage and Evaluation, Quality-of-Life Assessment, Survey Administration - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8 | Active not recruiting | University of Southern California | 173 | 2021-11-24 | 2026-10-05 | |
| 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases Computed Tomography, 18F-FMAU, Multiparametric Magnetic Resonance Imaging - Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8 | Early Phase 1 | Completed | University of Southern California | 10 | 2021-02-15 | 2024-05-24 |
| Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer Etoposide, Fludarabine Phosphate, Hematopoietic Cell Transplantation - Anaplastic Ependymoma, Atypical Teratoid/Rhabdoid Tumor | Phase 1 | Withdrawn | M.D. Anderson Cancer Center | 2021-01-14 | 2024-10-26 | |
| CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children Cyclophosphamide, Fludarabine, IL13Ralpha2-specific Hinge-optimized 41BB-co-stimulatory CAR Truncated CD19-expressing Autologous T-Lymphocytes - Malignant Brain Neoplasm, Recurrent Malignant Brain Neoplasm | Phase 1 | Recruiting | City of Hope Medical Center | 18 | 2020-12-11 | 2026-10-15 |
| Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers Computed Tomography, Gallium Ga 68 FAPi-46, Positron Emission Tomography - Bladder Carcinoma, Cervical Carcinoma | Phase 1 | Active not recruiting | Jonsson Comprehensive Cancer Center | 26 | 2020-08-27 | 2026-02-05 |
| Quantifying Oxygen Utilization of Tumors Using Oxygen-Enhanced Molecular MRI Arterial Spin Labeling Magnetic Resonance Imaging, pH-Weighted amine CEST, Oxygen-weighted SAGE-EPI - Malignant Brain Neoplasm | Not applicable | Terminated | Jonsson Comprehensive Cancer Center | 8 | 2020-07-07 | 2022-05-10 |
| Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study Biospecimen Collection, Genetic Counseling, Genetic Testing - Breast Carcinoma, Digestive System Neoplasm | Phase 1 | Completed | Mayo Clinic | 230 | 2020-06-29 | 2023-07-24 |
| Cancer Genetic Testing in Ethnic Populations Biospecimen Collection, Genetic Testing - Breast Carcinoma, Carcinoma of Unknown Primary | Not applicable | Recruiting | Mayo Clinic | 1800 | 2020-01-13 | 2026-04-02 |
| Pharmacogenomics Testing in the Optimal Use of Supportive Care Medications in Stage III-IV Cancer Biospecimen Collection, Genetic Testing, Quality-of-Life Assessment - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | Early Phase 1 | Completed | Mayo Clinic | 197 | 2019-06-06 | 2024-08-14 |
| Intravital Microscopy in Human Solid Tumors Diagnostic Microscopy, Fluorescein Sodium Injection - Solid Tumor, Adult, Clinical Stage IV Gastric Cancer AJCC v8 | Not applicable | Recruiting | Mayo Clinic | 85 | 2019-02-28 | 2026-06-02 |
Showing 20 of 21. Sign in to see all of them.
Brain Neoplasms (21) · Breast Neoplasms (6) · Colorectal Neoplasms (4) · Glioma (4) · Carcinoma, Hepatocellular (3) · Cholangiocarcinoma (3) · Lung Neoplasms (3) · Neoplasms, Unknown Primary (3) · Neuroendocrine Tumors (3) · Ovarian Neoplasms (3) · Pancreatic Neoplasms (3) · Prostatic Neoplasms (3) · Testicular Neoplasms (3) · Uterine Cervical Neoplasms (3) · Adrenal Gland Neoplasms (2)
Brain Diseases (21) · Central Nervous System Diseases (21) · Neoplasms (21) · Neoplasms by Site (21) · Nervous System Diseases (21) · Nervous System Neoplasms (21) · Central Nervous System Neoplasms (19) · Neoplasms by Histologic Type (10) · Neoplasms, Nerve Tissue (9) · Digestive System Diseases (8) · Neoplasms, Germ Cell and Embryonal (8) · Neoplasms, Glandular and Epithelial (8) · Neuroectodermal Tumors (8) · Digestive System Neoplasms (7) · Male Urogenital Diseases (7)
Magnetic Resonance Spectroscopy (8) · Specimen Handling (5) · Genetic Testing (3) · Calcium Dobesilate (2) · Dexamethasone (2) · FAPI-46 (2) · Fluorodeoxyglucose F18 (2) · auricularum (2) · dexamethasone 21-phosphate (2) · dexamethasone acetate (2) · Advance Care Planning (1) · Antilymphocyte Serum (1) · Cyclophosphamide (1) · Early Intervention, Educational (1) · Educational Status (1)
Mayo Clinic (9) · Jonsson Comprehensive Cancer Center (5) · City of Hope Medical Center (2) · University of Southern California (2) · Emory University (1) · M.D. Anderson Cancer Center (1) · Stanford University (1)
United States (20)
Jeremie Calais (2) · Jewel Samadder, M.D. (2) · Allison C. Rosenthal, DO (1) · Benjamin M Ellingson (1) · Dean A. Shumway, M.D. (1) · Derek R. Johnson, MD (1) · Emmanuel M Gabriel, M.D., Ph.D. (1) · Hossein Jadvar, MD (1) · Jana L Portnow, MD (1) · Jingwen Yao (1) · Kimberly Hoang, MD (1) · Kimberly Miller, PhD (1) · Kris M Mahadeo, MD (1) · Leo D Wang (1) · Lindsay Moore, MD (1)
PMID 12001988, PMID 17704903, PMID 19906081, PMID 19917863, PMID 20061178, PMID 20233873, PMID 20336386, PMID 20374484, PMID 20490982, PMID 20737573, PMID 21153378, PMID 21909917, PMID 21926464, PMID 22162570, PMID 23456602, PMID 24956510, PMID 25013744, PMID 26883450, PMID 2801858, PMID 33654117, PMID 37124504, PMID 3808620, PMID 42211793
P30CA014089 (2), P30CA016042 (2), P30CA033572 (2), P30CA138292 (1), P50CA211015 (1), R01CA190306 (1), R01CA267726 (1), R21CA303383 (1), R37CA256867 (1)