5 completed, 1 recruiting, 1 withdrawn. 7 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 5, Recruiting 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 4 |
Follow Major Depressive Episode: new trials by email Literature Review of Major Depressive Episode trials Research Report on Major Depressive Episode
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Remote Medical Monitoring of Patients With Depression Use of ThIA Medical Device - Depression Chronic, Depression and Quality of Life | Phase 1 | Recruiting | ThIA Santé Mentale | 608 | 2026-04-01 | 2026-10-16 |
| Personalized Ultrasonic Brain Stimulation for Depression (R61) LTFUS to SCC, LTFUS to ALIC - Major Depressive Episode, Depression - Major Depressive Disorder | Phase 1 / Phase 2 | Completed | Brian Mickey | 39 | 2025-03-10 | 2026-11-03 |
| Personalized Ultrasonic Brain Stimulation for Depression Diadem prototype - Major Depressive Episode | Phase 1 / Phase 2 | Completed | University of Utah | 22 | 2022-07-15 | 2026-09-09 |
| Glabellar Botulinum Toxin Injections for the Treatment of Geriatric Depression botulinum toxin A, Placebos - Major Depressive Disorder, Major Depressive Episode | Phase 1 | Withdrawn | Helse Stavanger HF | 2019-05-01 | 2021-08-11 | |
| Ketamine as an Adjunctive Therapy for Major Depression Ketamine, Midazolam - Major Depressive Episode, Unipolar Depression | Phase 1 | Completed | St Patrick's Hospital, Ireland | 25 | 2017-09-07 | 2020-01-18 |
| Ketamine for Suicidality in Bipolar Depression Ketamine, Midazolam - Bipolar Disorder, Major Depressive Episode | Phase 1 / Phase 2 | Completed | New York State Psychiatric Institute | 16 | 2013-09-01 | 2020-03-11 |
| Study Comparing Magnetic Seizure Therapy (MST) to Electroconvulsive Therapy (ECT) for Depression in Older Adults MagVenture MagPro MST, RUL ECT - Depression, Major Depressive Episode | Phase 1 / Phase 2 | Completed | New York State Psychiatric Institute | 18 | 2012-08-01 | 2020-09-03 |
Depression (4) · Bipolar Disorder (3) · Depressive Disorder (1) · Depressive Disorder, Major (1) · Depressive Disorder, Treatment-Resistant (1) · Psychological Well-Being (1) · Suicidal Ideation (1) · Suicide (1)
Behavior (4) · Behavioral Symptoms (4) · Mental Disorders (4) · Mood Disorders (4) · Bipolar and Related Disorders (3) · Depressive Disorder (1) · Personal Satisfaction (1) · Self-Injurious Behavior (1)
Ketamine (2) · Midazolam (2) · Botulinum Toxins, Type A (1) · Sodium Chloride (1)
New York State Psychiatric Institute (2) · Brian Mickey (1) · Helse Stavanger HF (1) · St Patrick's Hospital, Ireland (1) · ThIA Santé Mentale (1) · University of Utah (1)
United States (4) · France (1) · Ireland (1)
Brian J Mickey (1) · Brian J Mickey, MD, PhD (1) · Declan M McLoughlin, PhD (1) · Michael F Grunebaum, M.D. (1) · Stefan B Rowny, MD, MFA (1)
PMID 34131914, PMID 35036831, PMID 37891643, PMID 39428602
2016 (1), R61MH134943 (1)