6 completed, 4 recruiting, 3 active not recruiting, 3 unknown. 15 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 5, Recruiting 4, Active not recruiting 3, Unknown 3 |
| Early Phase 1 | 1 | Completed 1 |
Follow Lower Limb Amputation Knee: new trials by email Literature Review of Lower Limb Amputation Knee trials Research Report on Lower Limb Amputation Knee
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prosthetic Performance Enhancement Trial Flat terrain locomotor training, Uneven terrain locomotor training - Amputation, Lower Limb Amputation Below Knee (Injury) | Not applicable | Recruiting | University of Nevada, Las Vegas | 35 | 2025-06-26 | 2026-06-23 |
| Clinical Application Observation on the Evaluation of Phantom Limb Pain With the Suralis System Vibrotactile sensory feedback - Phantom Limb Pain After Amputation, Lower Limb Amputation Above Knee | Not applicable | Recruiting | Median | 20 | 2025-04-01 | 2026-01-07 |
| Clinical and Functional Assessment of Patients With Transfemoral Amputation Treated With Osteointegrated Implant osseointegrated surgery for transfemoral amputation - Prosthesis, Lower Limb Amputation Knee | Not applicable | Recruiting | Istituto Ortopedico Rizzoli | 15 | 2025-01-31 | 2026-11-10 |
| Promoting Physical Activity Following Dysvascular Amputation IMPACT-L3 - Amputation, Lower Limb Amputation Knee | Not applicable | Recruiting | West Park Healthcare Centre | 40 | 2025-01-23 | 2025-02-24 |
| Virtual Reality Rehabilitation to Promote Motor Recovery in Amputees Virtual environment practiced on the Caren, Conventional physiotherapy - Lower Limb Amputation Knee, Injuries | Not applicable | Unknown | IRCCS Centro Neurolesi Bonino Pulejo | 24 | 2024-03-01 | 2024-03-06 |
| Self-Management for Amputee Rehabilitation Using Technology. SMART, Control - Behavior, Amputation | Not applicable | Unknown | University of British Columbia | 82 | 2022-10-14 | 2024-07-23 |
| The Effect of Ischemic Conditioning on Strength and Ambulation in Subjects with PAD Ischemic Conditioning Low - Sham Comparator, Ischemic Conditioning High - Active Comparator - Peripheral Arterial Disease, Peripheral Vascular Disease | Not applicable | Completed | University of Illinois at Chicago | 21 | 2022-07-01 | 2025-02-27 |
| Validity and Reliability of The 3-Meter Backward Walk Test in Individuals With Lower Limb Amputation 3 meter backward walk test - Lower Limb Amputation Knee, Lower Limb Amputation Below Knee (Injury) | Not applicable | Completed | Tezel Yıldırım Şahan | 30 | 2021-08-05 | 2022-03-16 |
| Assessing Outcomes With Microprocessor Knee Utilization in a K2 Population Kenevo or C-Leg 4, Non microprocessor controlled knee (NMPK) - Lower Limb Amputation Above Knee (Injury), Congenital Amputation of Lower Limb | Not applicable | Active not recruiting | Otto Bock Healthcare Products GmbH | 107 | 2021-06-11 | 2024-02-09 |
| VR to Evaluate Phantom Limb Pain Coapt Phantom Limb Pain Management System - Phantom Limb Pain, Phantom Pain | Not applicable | Active not recruiting | Shirley Ryan AbilityLab | 48 | 2020-10-01 | 2025-03-14 |
| Feasibility Study to Evaluate a New Energy Storage and Return Prosthetic Foot Revo-M, Taleo, Proflex XC - Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Above Knee (Injury) | Not applicable | Completed | Otto Bock Healthcare Products GmbH | 27 | 2020-03-10 | 2024-09-23 |
| TeleEducation for Implementing a Clinical Practice Guideline For Amputees Telehealth-based strategy - Clinical Practice Guidelines, Lower Limb Amputation Above Knee (Injury) | Not applicable | Completed | Grupo Rehabilitacion en Salud | 7 | 2020-01-01 | 2022-11-07 |
| Enhancing Abilities in Amputees and Patients With Peripheral Neuropathy Through Restoration of Sensory Feedback Sensory Feedback - Lower Limb Amputation Knee, Lower Limb Amputation Above Knee (Injury) | Not applicable | Unknown | ETH Zurich | 20 | 2019-12-13 | 2024-02-20 |
| Reverse Innovation in Western Health Care: the ReMotion Prosthetic Knee. ReMotion Knee - Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Knee | Not applicable | Completed | Sint Maartenskliniek | 9 | 2019-02-27 | 2021-01-07 |
| Wearable Airbag Technology to Mitigate Falls in Individuals With High Fall Risk Airbag Belt Fall Protection System - Stroke, Parkinson Disease | Not applicable | Active not recruiting | Shirley Ryan AbilityLab | 200 | 2018-01-14 | 2025-12-29 |
| N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes Active Arm N-acetyl cysteine (NAC), Placebo Arm - Diabetes Mellitus, Critical Limb Ischemia | Early Phase 1 | Completed | Washington University School of Medicine | 33 | 2017-03-01 | 2024-08-16 |
Wounds and Injuries (11) · Diabetes Mellitus (2) · Peripheral Arterial Disease (2) · Phantom Limb (2) · Agnosia (1) · Behavior (1) · Chronic Limb-Threatening Ischemia (1) · Motor Activity (1) · Parkinson Disease (1) · Peripheral Vascular Diseases (1) · Stroke (1)
Cardiovascular Diseases (3) · Nervous System Diseases (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Vascular Diseases (3) · Arterial Occlusive Diseases (2) · Arteriosclerosis (2) · Atherosclerosis (2) · Endocrine System Diseases (2) · Glucose Metabolism Disorders (2) · Metabolic Diseases (2) · Neurobehavioral Manifestations (2) · Neurologic Manifestations (2) · Nutritional and Metabolic Diseases (2) · Pain (2)
Acetylcysteine (1)
Otto Bock Healthcare Products GmbH (2) · Shirley Ryan AbilityLab (2) · ETH Zurich (1) · Grupo Rehabilitacion en Salud (1) · IRCCS Centro Neurolesi Bonino Pulejo (1) · Istituto Ortopedico Rizzoli (1) · Median (1) · Sint Maartenskliniek (1) · Tezel Yıldırım Şahan (1) · University of British Columbia (1) · University of Illinois at Chicago (1) · University of Nevada, Las Vegas (1) · Washington University School of Medicine (1) · West Park Healthcare Centre (1)
United States (7) · Canada (2) · Italy (2) · Colombia (1) · Germany (1) · Netherlands (1) · Switzerland (1) · Turkey (Türkiye) (1)
Andreas Kannenberg, MD, PhD (1) · Arun Jayaraman, PT, PhD (1) · Crystal MacKay, PhD (1) · Giuseppe Paladina, PT (1) · Jenny A Kent, PhD, CSci (1) · Levi Hargrove, PhD (1) · Lindsay Slater, PhD (1) · Mohamed Zayed, MD (1) · Shane Wurdeman, PhD (1) · William C Miller, PhD (1)