1 active not recruiting, 1 completed, 1 not yet recruiting. 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Active not recruiting 1, Completed 1, Not yet recruiting 1 |
Follow Locally Advanced Gastrointestinal Stromal Tumor: new trials by email Literature Review of Locally Advanced Gastrointestinal Stromal Tumor trials Research Report on Locally Advanced Gastrointestinal Stromal Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Autologous Tumor Infiltrating Lymphocytes With Interleukin-2 for the Treatment of Locally Advanced, Recurrent or Metastatic Gastrointestinal Stromal Tumors Aldesleukin, Biospecimen Collection, Chest Radiography - Locally Advanced Gastrointestinal Stromal Tumor, Metastatic Gastrointestinal Stromal Tumor | Phase 2 | Not yet recruiting | Joal Beane | 59 | 2027-02-15 | 2026-10-13 |
| Testing the Anti-cancer Drug, Rogaratinib (BAY 1163877), for Treatment of Advanced Sarcoma With Alteration in Fibroblast Growth Factor Receptor (FGFR 1-4), and in Patients With SDH-deficient Gastrointestinal Stromal Tumor (GIST) Biopsy Procedure, Biospecimen Collection, Computed Tomography - Locally Advanced Gastrointestinal Stromal Tumor, Locally Advanced Sarcoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 48 | 2021-05-03 | 2026-07-31 |
| Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery Ipilimumab, Laboratory Biomarker Analysis, Nivolumab - Locally Advanced Bone Sarcoma, Locally Advanced Dedifferentiated Liposarcoma | Phase 2 | Completed | National Cancer Institute (NCI) | 164 | 2015-08-13 | 2023-10-17 |
Gastrointestinal Stromal Tumors (2) · Sarcoma (2) · Bone Neoplasms (1) · Histiocytoma, Malignant Fibrous (1) · Liposarcoma (1)
Neoplasms (3) · Neoplasms by Histologic Type (3) · Neoplasms, Connective Tissue (3) · Neoplasms, Connective and Soft Tissue (3) · Digestive System Diseases (2) · Digestive System Neoplasms (2) · Gastrointestinal Diseases (2) · Gastrointestinal Neoplasms (2) · Bone Diseases (1) · Histiocytoma (1) · Musculoskeletal Diseases (1) · Neoplasms by Site (1) · Neoplasms, Adipose Tissue (1) · Neoplasms, Fibrous Tissue (1)
Magnetic Resonance Spectroscopy (2) · Specimen Handling (2) · Biopsy (1) · CTLA-4 Antigen (1) · Cyclophosphamide (1) · Filgrastim (1) · Granulocyte Colony-Stimulating Factor (1) · Ipilimumab (1) · Nivolumab (1) · Rogaratinib (1) · Surgical Procedures, Operative (1) · X-Rays (1) · aldesleukin (1) · fludarabine (1)
National Cancer Institute (NCI) (2) · Joal Beane (1)
United States (3)
Joal Beane, MD (1) · Sandra P D'Angelo (1) · Suzanne George (1)
PMID 29370992, PMID 38573872, PMID 39343511, PMID 42191879
U10CA180821 (1), UM1CA186709 (1)