4 terminated. 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Terminated 4 |
Follow Liver Failure: new trials by email Literature Review of Liver Failure trials Research Report on Liver Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5% SMT + PE-A 5%, Standard Medical Treatment - Acute-On-Chronic Liver Failure | Phase 3 | Terminated | Instituto Grifols, S.A. | 274 | 2019-06-17 | 2026-06-04 |
| To Assess Safety/Efficacy of ELAD in Subjects w/ Severe Acute Alcoholic Hepatitis (sAAH) and Lille Score Failure ELAD, Standard of Care treatment - Severe Acute Alcoholic Hepatitis | Phase 3 | Terminated | Vital Therapies, Inc. | 18 | 2014-04-01 | 2019-02-19 |
| A Pilot Trial of Pediatric Liver Transplantation Without Steroids methyl prednisolone, hydrocortisone, prednisolone, No steroids - Evidence of Liver Transplantation | Phase 3 | Terminated | Birmingham Women's and Children's NHS Foundation Trust | 15 | 2008-06-01 | 2017-01-20 |
| RICE Trial: Rifaximin In Chronic Hepatic Encephalopathy - A Randomized, Controlled Trial Rifaximin, Lactulose, Placebo - Hepatic Encephalopathy | Phase 3 | Terminated | University of Miami | 13 | 2006-08-01 | 2019-09-17 |
Acute-On-Chronic Liver Failure (1) · End Stage Liver Disease (1) · Hepatic Encephalopathy (1) · Hepatitis, Alcoholic (1)
Digestive System Diseases (4) · Hepatic Insufficiency (4) · Liver Diseases (4) · Alcohol-Induced Disorders (1) · Alcohol-Related Disorders (1) · Brain Diseases (1) · Brain Diseases, Metabolic (1) · Central Nervous System Diseases (1) · Chemically-Induced Disorders (1) · Hepatitis (1) · Liver Diseases, Alcoholic (1) · Liver Failure, Acute (1) · Metabolic Diseases (1) · Nervous System Diseases (1)
Hydrocortisone (1) · Lactulose (1) · Prednisolone (1) · Rifaximin (1)
Birmingham Women's and Children's NHS Foundation Trust (1) · Instituto Grifols, S.A. (1) · University of Miami (1) · Vital Therapies, Inc. (1)
United Kingdom (3) · United States (3) · Germany (2) · Spain (2) · Austria (1) · Belgium (1) · France (1) · Italy (1) · Portugal (1)
Alexander Kuo, MD (1) · Andres Duarte-Rojo, MD (1) · Anne M Larson, MD (1) · Anupama Duddempudi, MD (1) · Chakradhar Reddy, MD (1) · David J Kramer, MD (1) · David Reich, MD (1) · Eckart Schott, MD (1) · Jan Stange, MD (1) · Javier Crespo, MD (1) · Joanna Sayer, MD (1) · Juan Caballeria, MD (1)