5 completed. 5 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 5 |
| Phase 2 | 1 | Completed 1 |
Follow Liver Failure, Acute: new trials by email Literature Review of Liver Failure, Acute trials Research Report on Liver Failure, Acute
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF 13C-Methacetin - Acute Liver Failure | Phase 2 / Phase 3 | Completed | University of Texas Southwestern Medical Center | 76 | 2016-06-10 | 2020-12-22 |
| Efficacy of Granulocyte Colony-stimulating Factor and Erythropoetin for Patients With Acute-on-chronic Liver Failure Granulocyte Colony-stimulating Factor (G-CSF) and Erythropoetin (EPO), Placebo - Acute on Chronic Hepatic Failure | Phase 3 | Completed | Institute of Liver and Biliary Sciences, India | 55 | 2011-07-01 | 2016-12-06 |
| The MARS® Albumin Dialysis System in Patients With Fulminant and Subfulminant Hepatic Failure Molecular Adsorbent Recirculating System (MARS®) - Hepatitis | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 110 | 2004-08-01 | 2011-02-17 |
| N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver Failure N-acetylcysteine, Placebo - Acute Liver Failure, Hepatic Encephalopathy | Phase 3 | Completed | University of Pittsburgh | 184 | 2000-01-01 | 2016-07-28 |
| Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen N-acetylcysteine (NAC), Placebo - Acute Liver Failure | Phase 3 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 173 | 1998-06-01 | 2017-10-13 |
Hepatic Encephalopathy (2) · Acute-On-Chronic Liver Failure (1) · Fibrosis (1) · Gastrointestinal Diseases (1) · Hepatitis (1) · Massive Hepatic Necrosis (1) · Rare Diseases (1)
Digestive System Diseases (5) · Hepatic Insufficiency (5) · Liver Diseases (5) · Liver Failure (5) · Brain Diseases (2) · Brain Diseases, Metabolic (2) · Central Nervous System Diseases (2) · Metabolic Diseases (2) · Nervous System Diseases (2) · Nutritional and Metabolic Diseases (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Chemical and Drug Induced Liver Injury (1) · Disease Attributes (1)
Acetylcysteine (2) · Glucose (1) · Granulocyte Colony-Stimulating Factor (1) · Water (1)
Assistance Publique - Hôpitaux de Paris (1) · Institute of Liver and Biliary Sciences, India (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · University of Pittsburgh (1) · University of Texas Southwestern Medical Center (1)
United States (3) · Canada (1) · France (1) · India (1) · United Kingdom (1)
Robert H Squires, M.D. (1) · Robert J. Fontana, MD (1) · Shiv Kumar Sarin, MD, DM (1) · William M. Lee, MD (1)
PMID 37183883, PMID 19524577, PMID 24126646, PMID 31421008
U01DK058369 (2), R01DK058369 (1), R03DK052827 (1), U01DK072146 (1)