delgocitinib: Clinical Trials

7 completed, 2 not yet recruiting, 2 recruiting. 5 Phase 3, 3 Phase 2, 2 Phase 1, 1 Early Phase 1.

By phase and status

Phase	Trials	Status
Phase 3	5	Completed 4, Recruiting 1
Phase 2	3	Not yet recruiting 2, Recruiting 1
Phase 1	2	Completed 2
Early Phase 1	1	Completed 1

Follow delgocitinib: new trials by email Literature Review of delgocitinib trials Research Report on delgocitinib

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Trial of Delgocitinib 20 mg/g Cream in Subjects With Frontal Fibrosing Alopecia (FFA) Delgocitinib - Frontal Fibrosing Alopecia	Phase 2	Not yet recruiting	Maryanne Makredes Senna	30	2026-09-10	2026-08-26
Topical JAK-Inhibition of Early-Stage CTCL delgocitinib - Mycosis Fungoides, Cutaneous T-cell Lymphoma	Phase 2	Not yet recruiting	Aarhus University Hospital	15	2026-09-01	2026-08-26
Safety and Biomarker Responses of Delgocitinib (JAK1,2,3/TYK2 Inhibitor) in Central Centrifugal Cicatricial Alopecia and Lichen Planopilaris Delgocitinib - Central Centrifugal Cicatricial Alopecia, Lichen Planopilaris	Phase 2	Recruiting	Icahn School of Medicine at Mount Sinai	30	2026-05-19	2026-07-10
A 52-Week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream in Adult Participants With Lichen Sclerosus Delgocitinib, Cream Vehicle - Lichen Sclerosus	Phase 3	Recruiting	LEO Pharma	652	2026-05-01	2026-10-13
A Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Delgocitinib Cream in Chinese Adults and Adolescents With Moderate to Severe Chronic Hand Eczema Delgocitinib, Vehicle cream - Chronic Hand Eczema	Phase 3	Completed	LEO Pharma	362	2023-09-05	2025-09-25
Pharmacokinetics of Delgocitinib 20 mg/g Cream in Subjects With Chronic Hand Eczema Delgocitinib - Chronic Hand Eczema	Phase 1	Completed	LEO Pharma	15	2022-09-06	2025-04-04
Efficacy and Safety of Delgocitinib Cream in Adolescents 12-17 Years of Age With Moderate to Severe Chronic Hand Eczema Delgocitinib, Cream vehicle - Chronic Hand Eczema	Phase 3	Completed	LEO Pharma	98	2022-07-14	2026-08-21
A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand Eczema Delgocitinib, Toctino - Chronic Hand Eczema	Phase 3	Completed	LEO Pharma	513	2022-06-15	2025-05-09
A Trial to Evaluate the Effect of Delgocitinib on the Heart Rhythm of Healthy People Delgocitinib capsule, Placebo capsule - Healthy	Early Phase 1	Completed	LEO Pharma	40	2021-09-29	2026-04-28
Open-label Multi-site Extension Trial in Subjects Who Completed the DELTA 1 or DELTA 2 Trials Delgocitinib - Chronic Hand Eczema	Phase 3	Completed	LEO Pharma	801	2021-08-23	2025-04-08
Delgocitinib Cream for the Treatment of Moderate to Severe Atopic Dermatitis During 8 Weeks in Adults, Adolescents, and Children delgocitinib - Atopic Dermatitis	Phase 1	Completed	LEO Pharma	46	2019-02-20	2025-02-24

Conditions studied

Alopecia (1)  ·  Dermatitis, Atopic (1)  ·  Eczema (1)  ·  Lichen Planus (1)  ·  Lichen Sclerosus et Atrophicus (1)  ·  Lymphoma, T-Cell, Cutaneous (1)  ·  Mycosis Fungoides (1)  ·  Skin Diseases (1)

Sponsors

LEO Pharma (8)  ·  Aarhus University Hospital (1)  ·  Icahn School of Medicine at Mount Sinai (1)  ·  Maryanne Makredes Senna (1)

Countries

Canada (5)  ·  United Kingdom (5)  ·  United States (4)  ·  France (3)  ·  Germany (3)  ·  Poland (3)  ·  Spain (3)  ·  Belgium (2)  ·  Italy (2)  ·  Australia (1)  ·  Austria (1)  ·  China (1)  ·  Denmark (1)  ·  Netherlands (1)  ·  Norway (1)

Top investigators

Benjamin Ungar, MD (1)  ·  Elisabeth Linde Grove, MD (1)  ·  Rikke Bech, MD, PhD (1)

Results publications

PMID 40525591, PMID 40081663, PMID 40252681, PMID 42143645, PMID 42235562

NIH funding

2025 (2)