5 terminated. 5 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Terminated 5 |
| Phase 1 | 2 | Terminated 2 |
| Phase 3 | 1 | Terminated 1 |
Follow Ischemic Cardiomyopathy: new trials by email Literature Review of Ischemic Cardiomyopathy trials Research Report on Ischemic Cardiomyopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1/2 Study of High-dose Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure MYDICAR Phase 1, MYDICAR Phase 2, Placebo Phase 2 only - Ischemic Cardiomyopathy, Non-ischemic Cardiomyopathy | Phase 1 / Phase 2 | Terminated | Celladon Corporation | 9 | 2015-04-01 | 2017-01-31 |
| AAV1-CMV-Serca2a GENe Therapy Trial in Heart Failure MYDICAR-single intracoronary infusion, Placebo; single intracoronary infusion - Heart Failure Congestive, Ischemic Cardiomyopathy | Phase 2 | Terminated | Assistance Publique - Hôpitaux de Paris | 10 | 2013-12-01 | 2017-08-29 |
| Left Ventricular Assist Device Combined With Allogeneic Mesenchymal Stem Cells Implantation in Patients With End-stage Heart Failure. Allogeneic stem cells implantation - Heart Failure, Ischemic Cardiomyopathy | Phase 2 / Phase 3 | Terminated | AHEPA University Hospital | 1 | 2012-10-01 | 2022-07-25 |
| Optimized Biventricular Pacing Allograft Recipients BiVP, AAI Pacing - Dilated Cardiomyopathy, Ischemic Cardiomyopathy | Phase 1 / Phase 2 | Terminated | Henry M. Spotnitz | 12 | 2007-01-01 | 2016-10-06 |
| Study to Examine the Safety and Effectiveness of Implanted Skeletal Muscle Cells (Cells Removed From the Thigh Muscle) Into Scarred Areas of Heart Muscle After Heart Attack. Cellular Therapy (Cultured Autologous Skeletal Myoblast Transplantation) - Ischemic Heart Failure, Ischemic Heart Disease | Phase 2 | Terminated | Genzyme, a Sanofi Company | 2002-11-01 | 2015-05-22 |
Heart Failure (4) · Cardiomyopathies (2) · Cardiomegaly (1) · Cardiomyopathy, Dilated (1) · Cardiovascular Diseases (1) · Coronary Artery Disease (1) · Heart Diseases (1) · Myocardial Ischemia (1)
Cardiovascular Diseases (4) · Heart Diseases (4) · Vascular Diseases (2) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Cardiomegaly (1) · Cardiomyopathies (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Coronary Disease (1) · Genetic Diseases, Inborn (1) · Hypertrophy (1) · Laminopathies (1) · Myocardial Ischemia (1) · Pathological Conditions, Anatomical (1) · Pathological Conditions, Signs and Symptoms (1)
Cardiac Resynchronization Therapy (1) · Cell- and Tissue-Based Therapy (1)
AHEPA University Hospital (1) · Assistance Publique - Hôpitaux de Paris (1) · Celladon Corporation (1) · Genzyme, a Sanofi Company (1) · Henry M. Spotnitz (1)
France (2) · United States (2) · Belgium (1) · Germany (1) · Greece (1) · Italy (1) · Switzerland (1) · United Kingdom (1)
Henry M Spotnitz, MD (1) · Kyriakos Anastasiadis, MD, PhD, FETCS (1)
R01HL080152 (1)