2 completed, 2 terminated, 1 recruiting, 1 unknown. 7 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 2, Terminated 2, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 4 | Terminated 2, Recruiting 1, Unknown 1 |
Follow Ileitis: new trials by email Literature Review of Ileitis trials Research Report on Ileitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF) EXE-346, Placebo - Ileal Pouch | Phase 1 / Phase 2 | Recruiting | Exegi Pharma, LLC | 50 | 2023-11-06 | 2026-05-28 |
| Stem Cells for the Treatment of Pouchitis Mesenchymal Stem Cells (MSCs) - Pouchitis, Crohn's Disease | Phase 1 | Withdrawn | The Cleveland Clinic | 2022-04-01 | 2026-04-16 | |
| GM-CSF, Fosfomycin and Metronidazole for Pouchitis in Ulcerative Colitis Patients After Restorative IPAA Surgery GM-CSF, fosfomycin and metronidazole - Pouchitis | Phase 1 / Phase 2 | Unknown | Zealand University Hospital | 18 | 2021-09-06 | 2023-01-26 |
| Safety and Efficacy of Fecal Microbiome Transplantation (FMT) in the Treatment of Antibiotic Dependent Pouchitis (ADP) Active FMT, then open label FMT, Placebo FMT, then open label FMT - Pouchitis | Phase 1 / Phase 2 | Terminated | University of North Carolina, Chapel Hill | 6 | 2017-06-01 | 2019-05-14 |
| Study of Sc-FOS for Pouchitis Prevention Short-Chain Fructooligosaccharide, Maltodextrin - Pouchitis | Phase 1 | Completed | Mayo Clinic | 13 | 2014-08-01 | 2020-02-24 |
| Evaluate PF-00547659 On Cerebrospinal Fluid Lymphocytes In Volunteers With Crohn's Disease Or Ulcerative Colitis Who Failed Or Did Not Tolerate Anti-TNFs lumbar puncture - Crohn's Disease, Ileitis | Phase 1 | Completed | Shire | 49 | 2012-05-03 | 2021-06-03 |
| Clotrimazole Enemas for Pouchitis in Children and Adults Clotrimazole - Ulcerative Colitis, Pouchitis | Phase 1 / Phase 2 | Terminated | Web | 11 | 2002-09-30 | 2022-12-09 |
Pouchitis (6) · Colitis, Ulcerative (3) · Crohn Disease (2) · Inflammatory Bowel Diseases (2) · Colitis (1)
Digestive System Diseases (7) · Enteritis (7) · Gastroenteritis (7) · Gastrointestinal Diseases (7) · Ileal Diseases (7) · Intestinal Diseases (7) · Colonic Diseases (3) · Colitis (2) · Inflammatory Bowel Diseases (1)
Clotrimazole (1) · Fosfomycin (1) · Granulocyte-Macrophage Colony-Stimulating Factor (1) · Metronidazole (1) · Spinal Puncture (1) · maltodextrin (1)
Exegi Pharma, LLC (1) · Mayo Clinic (1) · Shire (1) · The Cleveland Clinic (1) · University of North Carolina, Chapel Hill (1) · Web (1) · Zealand University Hospital (1)
United States (5) · Austria (1) · Belgium (1) · Denmark (1) · France (1) · Germany (1) · Netherlands (1)
Amy L Lightner, MD (1) · Hans Herfarth, MD, PhD (1) · Julia Collins, MS (1) · Laura Raffals, MD (1) · Paul A. Rufo, MD, MMSc (1)