5 completed, 2 terminated, 1 active not recruiting, 1 recruiting. 10 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 5, Terminated 2, Active not recruiting 1, Recruiting 1, Unknown 1 |
Follow Hypothalamic Neoplasms: new trials by email Literature Review of Hypothalamic Neoplasms trials Research Report on Hypothalamic Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Use of [18F] Fluoroethyl-L-tyrosine PET/MRI for Identifying Small Functional Pituitary Adenomas FET-PET/MRI - Pituitary Adenoma | Phase 1 | Recruiting | Mayo Clinic | 5 | 2026-01-08 | 2026-03-09 |
| Detection of PitNET Tissue During TSS Using Bevacizumab-800CW Bevacizumab-IRDye800CW, Molecular Fluorescence Endoscopy platform - Pituitary Tumor, Pituitary Adenoma | Phase 1 | Completed | University Medical Center Groningen | 20 | 2020-10-28 | 2023-04-14 |
| A First in Human Study Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers for Malignant Brain Tumors 89Zr-DFO-cRGDY-PEG-Cy5-C' dots PET Imaging, Blood and Urine samples - Brain Cancer, Pituitary Adenoma | Phase 1 | Active not recruiting | Memorial Sloan Kettering Cancer Center | 17 | 2018-03-07 | 2026-05-01 |
| Intraoperative Imaging of Pituitary Adenomas by OTL OTL38 - Neoplasms, Pituitary Neoplasms | Phase 1 | Terminated | University of Pennsylvania | 33 | 2015-10-01 | 2019-08-06 |
| Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors Photofrin (porfimer sodium) & photodynamic therapy. - Brain Tumor, Recurrent | Phase 1 | Completed | Harry T Whelan, MD | 5 | 2013-03-01 | 2019-02-25 |
| Detection of Functioning Pituitary Microadenoma: PET/MRI Versus PET/CT 18F-FDG - Pituitary Adenoma | Phase 1 | Unknown | Peking Union Medical College Hospital | 100 | 2013-02-01 | 2018-01-19 |
| Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia gamma-secretase/Notch signalling pathway inhibitor RO4929097, diagnostic laboratory biomarker analysis, pharmacological study - Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Choriocarcinoma | Phase 1 | Terminated | National Cancer Institute (NCI) | 129 | 2010-03-01 | 2014-11-05 |
| Fluorescence Guided Resection of Brain Tumors 5-aminolevulinic acid - Brain Tumors | Phase 1 | Completed | David W. Roberts | 105 | 2007-05-01 | 2019-06-14 |
| MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma entinostat - Cancer | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 75 | 2001-03-01 | 2012-03-15 |
| Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer yttrium Y 90-edotreotide - Brain and Central Nervous System Tumors, Breast Cancer | Phase 1 | Completed | Novartis Pharmaceuticals | 60 | 1998-01-01 | 2013-05-01 |
Pituitary Neoplasms (10) · Brain Neoplasms (5) · Astrocytoma (4) · Medulloblastoma (4) · Meningioma (4) · Oligodendroglioma (4) · Burkitt Lymphoma (3) · Choroid Plexus Neoplasms (3) · Craniopharyngioma (3) · Ependymoma (3) · Glioma (3) · Glioma, Subependymal (3) · Neoplasms (3) · Neuroectodermal Tumors, Primitive (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3)
Brain Diseases (10) · Central Nervous System Diseases (10) · Endocrine Gland Neoplasms (10) · Endocrine System Diseases (10) · Hypothalamic Diseases (10) · Neoplasms by Site (10) · Nervous System Diseases (10) · Nervous System Neoplasms (10) · Pituitary Diseases (10) · Supratentorial Neoplasms (10) · Central Nervous System Neoplasms (9) · Neoplasms (7) · Brain Neoplasms (5) · Neoplasms by Histologic Type (5)
2,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide (1) · 90Y-octreotide, DOTA-Tyr(3)- (1) · Aminolevulinic Acid (1) · Blood Specimen Collection (1) · Calcium Dobesilate (1) · Dexamethasone (1) · Dihematoporphyrin Ether (1) · Fluorodeoxyglucose F18 (1) · Pafolacianine (1) · Photochemotherapy (1) · entinostat (1)
David W. Roberts (1) · Harry T Whelan, MD (1) · Mayo Clinic (1) · Memorial Sloan Kettering Cancer Center (1) · National Cancer Institute (NCI) (1) · National Institutes of Health Clinical Center (CC) (1) · Novartis Pharmaceuticals (1) · Peking Union Medical College Hospital (1) · University Medical Center Groningen (1) · University of Pennsylvania (1)
United States (8) · Canada (1) · China (1) · Netherlands (1)
David W Roberts, MD (1) · Harry T Whelan, MD (1) · Jeff Knipstein, MD (1) · Keith Paulsen, PhD (1) · Larry K. Kvols, MD (1) · Najat Daw (1) · Neetu Soni, MBBS, MD (1) · Nelson Moss, MD (1) · Shivaani Kummar, MD (1) · Zhaohui Zhu, M.D.,PhD (1)
R01NS052274 (1), U01CA097452 (1)