3 completed, 2 withdrawn, 1 active not recruiting. 6 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 3, Withdrawn 2, Active not recruiting 1 |
| Phase 2 | 3 | Active not recruiting 1, Completed 1, Withdrawn 1 |
Follow Hypertrophic Scar: new trials by email Literature Review of Hypertrophic Scar trials Research Report on Hypertrophic Scar
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intra-lesional ACE Inhibitor for Treatment of Hypertrophic Scars Intralesional enalaprilat injection - Hypertrophic Scar | Phase 2 / Phase 3 | Withdrawn | Nova Scotia Health Authority | 2024-08-01 | 2025-02-17 | |
| Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization Botulinum Toxin, Normal saline - Scar, Hypertrophic Scar | Phase 2 / Phase 3 | Active not recruiting | Henry Ford Health System | 12 | 2022-06-01 | 2026-01-15 |
| The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar Formation Botulinum Toxins, Normal saline - Scar, Hypertrophic Scar | Phase 2 / Phase 3 | Completed | Henry Ford Health System | 22 | 2019-06-10 | 2025-06-15 |
| Silicone vs Pirfenidone in the Treatment of Hypertrophic Scars and Keloids pirfenidone 8% gel, silicon gel - Scars, Keloids | Phase 3 | Completed | Fundación Nacional para la Enseñanza y la Investigación de la Dermatología A.C. | 40 | 2015-07-14 | 2025-04-04 |
| Role of Topical Putrescine (Fibrostat) for Prevention of Hypertrophic Scars in Mammoplasty Patients 1,4-Diaminobutane, 10% Urea cream - Hypertrophic Scar | Phase 3 | Completed | University of Manitoba | 56 | 2011-09-02 | 2017-12-20 |
| Intron A for the Treatment of Hypertrophic Scar interferon alpha 2b - Burn, Hypertrophic Scar | Phase 3 | Withdrawn | University of Alberta | 2014-01-30 |
Cicatrix, Hypertrophic (6) · Cicatrix (4) · Keloid (2) · Breast Diseases (1) · Burns (1) · Gigantomastia (1) · Hypertrophy (1)
Fibrosis (6) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Skin and Connective Tissue Diseases (3) · Cicatrix (2) · Collagen Diseases (2) · Connective Tissue Diseases (2) · Pathological Conditions, Anatomical (1) · Skin Diseases (1) · Wounds and Injuries (1)
Botulinum Toxins (2) · Saline Solution (2) · abobotulinumtoxinA (2) · Enalaprilat (1) · Gels (1) · Interferon alpha-2 (1) · Introns (1) · Putrescine (1) · pirfenidone (1)
Henry Ford Health System (2) · Fundación Nacional para la Enseñanza y la Investigación de la Dermatología A.C. (1) · Nova Scotia Health Authority (1) · University of Alberta (1) · University of Manitoba (1)
United States (2) · Canada (1) · Mexico (1)
David Ozog, MD (2) · Edward E Tredget, MD MSc FRCSC (1) · Jose Contreras-Ruiz (1) · Michael Bezuhly, MD, MSc (1)
PMID 10077078, PMID 11242330, PMID 11348456, PMID 12845617, PMID 15253184, PMID 16079683, PMID 18534768, PMID 18555763, PMID 18843115, PMID 19215252, PMID 19341651, PMID 19621835, PMID 19802513, PMID 20009818, PMID 20440184, PMID 21332916, PMID 22090252, PMID 22177632, PMID 22907286, PMID 23027220, PMID 23102873, PMID 24501476, PMID 24898579, PMID 27639820, PMID 28539239, PMID 28654594, PMID 29401161, PMID 30087573, PMID 30548742, PMID 31155638, PMID 31164358, PMID 31385893, PMID 31513335, PMID 31881614, PMID 32813130, PMID 7917152