11 completed, 3 recruiting, 2 withdrawn. 7 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 6, Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Hypertensive Urgency: new trials by email Literature Review of Hypertensive Urgency trials Research Report on Hypertensive Urgency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension Tonlamarsen, Placebo - Hypertension, Acute Severe Hypertension | Phase 2 | Recruiting | Kardigan, Inc. | 140 | 2026-06-23 | 2026-10-15 |
| HYPERTENSIVE CRISIS AND ATMOSPHERIC PRESSURE RELATIONSHIP Hypertensive Urgency, Weather | Recruiting | Saglik Bilimleri Universitesi | 350 | 2024-09-15 | 2024-10-10 | |
| The Use of Virtual Reality and Music Therapy for Hypertensive Urgency Captopril 25Mg Tab, Virtual Reality Exposure, Classic Music Therapy - Hypertensive Urgency, Primary Hypertension | Not applicable | Completed | Ankara City Hospital Bilkent | 130 | 2024-08-01 | 2026-05-07 |
| Rural Hospital-Level Care at Home for Acutely Ill Adults Home Hospital care, Traditional Hospital care - Infections, Heart Failure | Not applicable | Completed | Brigham and Women's Hospital | 160 | 2022-02-16 | 2025-11-12 |
| Prediction of Patient Deterioration Using Machine Learning Traditional vital sign alarms versus the BioVitals Index vs the National Early Warning Score 2 - Infection, Heart Failure | Completed | Brigham and Women's Hospital | 526 | 2021-03-20 | 2026-03-17 | |
| Serum Potassium Prediction Using Machine Learning and Single-lead ECG Potassium estimation algorithm - Infection, Heart Failure | Withdrawn | Brigham and Women's Hospital | 2021-03-20 | 2026-03-25 | ||
| Prediction of Expected Length of Hospital Stay Using Machine Learning Infection, Heart Failure | Withdrawn | Brigham and Women's Hospital | 2021-03-20 | 2026-03-17 | ||
| Rural Home Hospital: Proof of Concept Home hospital care - Infection, Heart Failure | Not applicable | Completed | Brigham and Women's Hospital | 7 | 2021-02-18 | 2025-01-30 |
| Effect of Pursed-Lip Breathing on Blood Pressure and Heart Rate Non-pharmacologic treatment; Pursed-Lip Breathing Combined with Number Counting - Hypertensive Urgency | Not applicable | Completed | Khon Kaen University | 112 | 2019-09-01 | 2020-10-01 |
| Remote Physician Care for Home Hospital Patients Remote Visit - Infection, Heart Failure | Not applicable | Completed | Brigham and Women's Hospital | 172 | 2019-08-03 | 2020-11-30 |
| Home Hospital for Suddenly Ill Adults Home Hospitalization - Infection, Heart Failure | Not applicable | Recruiting | Brigham and Women's Hospital | 3000 | 2018-01-18 | 2026-03-17 |
| Hospital-Level Care at Home for Acutely Ill Adults Home hospitalization, Traditional inpatient hospitalization - Infection, Heart Failure | Not applicable | Completed | Brigham and Women's Hospital | 91 | 2017-06-06 | 2018-08-29 |
| Prediction of 30-Day Readmission Using Machine Learning Infection, Heart Failure | Completed | Brigham and Women's Hospital | 372 | 2017-06-01 | 2026-03-17 | |
| Telemedical Versus Conventional Emergency Care of Hypertensive Emergencies Telemedical care - Hypertensive Emergency, Hypertensive Urgency | Completed | RWTH Aachen University | 331 | 2013-11-01 | 2016-10-05 | |
| Evaluation of Intravenous Cardene(Nicardipine)and Labetalol Use in the Emergency Department nicardipine intravenous, Labetalol - Hypertensive Urgency | Phase 4 | Completed | The Cleveland Clinic | 226 | 2008-10-01 | 2015-01-06 |
| Risk Factors of Hypertensive Urgencies Hypertensive Urgency | Completed | Russian Cardiology Research and Production Center | 1200 | 2007-01-01 | 2008-12-09 |
Hypertensive Crisis (16) · Asthma (9) · Heart Failure (9) · Infections (9) · Pulmonary Disease, Chronic Obstructive (9) · Renal Insufficiency, Chronic (9) · Hypertension (4) · Emergencies (3) · Diabetes Mellitus (1) · Essential Hypertension (1) · Hypoventilation (1)
Cardiovascular Diseases (16) · Vascular Diseases (16) · Disease Attributes (12) · Hypertension (12) · Pathologic Processes (12) · Pathological Conditions, Signs and Symptoms (12) · Respiratory Tract Diseases (10) · Bronchial Diseases (9) · Chronic Disease (9) · Female Urogenital Diseases (9) · Female Urogenital Diseases and Pregnancy Complications (9) · Heart Diseases (9) · Hypersensitivity (9) · Hypersensitivity, Immediate (9) · Immune System Diseases (9)
Home Care Services, Hospital-Based (2) · Captopril (1) · Labetalol (1) · Nicardipine (1)
Brigham and Women's Hospital (9) · Ankara City Hospital Bilkent (1) · Kardigan, Inc. (1) · Khon Kaen University (1) · RWTH Aachen University (1) · Russian Cardiology Research and Production Center (1) · Saglik Bilimleri Universitesi (1) · The Cleveland Clinic (1)
United States (11) · Turkey (Türkiye) (2) · Canada (1) · Germany (1) · Russia (1) · Thailand (1)
David Levine, MD MPH MA (4) · Evgeniy I Chazov, MD (1) · Jeffrey Schnipper, MD, MPH (1) · Joseph Varon, MD (1) · W. Frank Peacock, MD (1)
PMID 12441212, PMID 21707983, PMID 23381792, PMID 23535700, PMID 25141250, PMID 27294333, PMID 31415308, PMID 31842232, PMID 32371787, PMID 33479931, PMID 33954888, PMID 34825613, PMID 36040741, PMID 36418425, PMID 37644380, PMID 38132649, PMID 41324962, PMID 42555132