87 completed, 12 terminated, 8 withdrawn, 4 unknown. 119 Phase 2, 22 Phase 1, 11 Phase 3.
Follow HIV Infection: new trials by email Literature Review of HIV Infection trials Research Report on HIV Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DOR/ISL in Pediatric Participants With HIV-1, <18 Years of Age and ≥ 35 kg DOR/ISL - HIV-1, HIV Infection | Phase 2 | Not yet recruiting | Merck Sharp & Dohme LLC | 45 | 2026-12-23 | 2026-10-07 |
| Baricitinib Curative Repression of HIV-1 Antiretroviral Therapy (ART), Baricitinib (LY3009104) 2 mg, Baricitinib (LY3009104) 4 mg - HIV Infection, HIV | Phase 2 | Not yet recruiting | Emory University | 35 | 2026-10-01 | 2026-08-17 |
| Colchicine to Reduce Coronary Artery Inflammation in People With HIV Colchicine 0.5 mg, Placebo - HIV Infection, Cardiovascular Diseases (CVD) | Phase 2 | Recruiting | Instituto de Investigación Hospital Universitario La Paz | 90 | 2026-06-01 | 2026-07-15 |
| UNIVERSAL 1: Pharmacokinetic Study of a Novel DTG/FTC/TAF Dose Ratio for Children dolutegravir (DTG)/emtricitabine (FTC)/tenofovir alafenamide (TAF) regimen, Dolutegravir (DTG)/ Emtricitabine (FTC)/tenofovir alafenamide (TAF) - HIV Infection | Phase 2 | Completed | PENTA Foundation | 53 | 2024-12-11 | 2026-03-04 |
| Effectivity of Protein Purified Derivative Treatment for Anogenital Warts in HIV Patient Injection of protein purified derivative - Anogenital Warts, HIV Infection | Phase 2 / Phase 3 | Unknown | Universitas Padjadjaran | 30 | 2024-09-15 | 2024-09-19 |
| Clinical Trial to Evaluate the Efficacy and Safety of Codivir® in Addition to Standard Antiretroviral Treatment for HIV Infection in Antiretroviral-naïve Participants ICF, Eligibility Assessment, Demographic data - HIV, HIV Infection | Phase 2 | Recruiting | Code Pharma | 40 | 2023-07-20 | 2024-11-06 |
| Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancers Fludarabine, Cyclophosphamide, Thiotepa - Acute Erythroid Leukemia, Acute Lymphoblastic Leukemia | Phase 2 | Terminated | Fred Hutchinson Cancer Center | 1 | 2022-10-06 | 2025-01-01 |
| Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer Anoscopy, Biospecimen Collection, Capecitabine - AIDS-Related Anal Carcinoma, Anal Margin Squamous Cell Carcinoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 40 | 2022-08-09 | 2026-10-05 |
| Immunomodulation Using VB-201 to Reduce Arterial Inflammation in Treated HIV - VITAL HIV Trial VB-201, Placebo - Inflammation, HIV Infection | Phase 1 / Phase 2 | Withdrawn | Priscilla Hsue, MD | 2022-07-01 | 2022-09-15 | |
| Testing the Addition of Paclitaxel and Carboplatin Given After Standard Chemotherapy and Radiation for Cervical Cancer in HIV-positive Women Carboplatin, Cisplatin, Paclitaxel - Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma | Phase 2 | Withdrawn | AIDS Malignancy Consortium | 2022-05-31 | 2022-06-21 | |
| Immune Therapy and Analytical Treatment Interruption in HIV+ Participants Who Received an Allogeneic Stem Cell Transplantation Analytical Treatment Interruption + bNAbs infusion - HIV Infection | Phase 2 | Withdrawn | IrsiCaixa | 2021-02-28 | 2022-08-03 | |
| Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals Dolutegravir (DTG), Isoniazid (INH), Rifapentine (RPT) - HIV Infection, LTBI | Phase 2 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 37 | 2021-02-27 | 2024-09-19 |
| Glecaprevir/Pibrentasvir Fixed-dose Combination Treatment for Acute Hepatitis C Virus Infection Glecaprevir/Pibrentasvir (G/P) - Hepatitis C Infection, HIV Infection | Phase 2 | Completed | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 45 | 2019-11-20 | 2024-07-11 |
| Dual bNAb Treatment in Children ART, VRC01LS, 10-1074 - HIV Infection | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 30 | 2019-06-17 | 2026-05-04 |
| HIV Reservoir Reduction With Interleukin-2 Recombinant Interleukin-2 - HIV Infection | Phase 2 | Terminated | Case Western Reserve University | 9 | 2019-04-01 | 2022-09-28 |
| St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Nalmefene Low dose naltrexone, Nalmefene - HIV Infection, Alcohol Use | Phase 1 / Phase 2 | Completed | Boston Medical Center | 11 | 2018-07-03 | 2020-08-24 |
| Studying Partial-agonists for Ethanol and Tobacco Elimination in Russians With HIV (St PETER HIV) Varenicline, Cytisine, Nicotine Replacement Therapy - HIV Infection, Alcohol Use | Phase 2 / Phase 3 | Completed | Boston Medical Center | 400 | 2017-07-19 | 2020-12-17 |
| Microbiota Restoration Therapy in HIV With Repeated Low-Dose Interventions FMT, Placebo - HIV Infection | Phase 1 / Phase 2 | Completed | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 30 | 2017-01-01 | 2018-10-30 |
| High Intensity Lipid Lowering Following Acute Coronary Syndromes for Persons Living With HIV Pravastatin, Rosuvastatin - HIV Infection, Coronary Heart Disease | Phase 2 | Completed | Matthew Feinstein | 10 | 2016-11-01 | 2022-10-18 |
| ODYSSEY (PENTA 20) Dolutegravir, Standard of Care - HIV Infection | Phase 2 / Phase 3 | Completed | PENTA Foundation | 792 | 2016-09-20 | 2025-07-29 |
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HIV Infections (119) · Acquired Immunodeficiency Syndrome (12) · Hepatitis C (8) · Inflammation (6) · Infections (4) · Cardiovascular Diseases (3) · AIDS-related Kaposi sarcoma (2) · Alcohol Drinking (2) · Anus Neoplasms (2) · Coronary Disease (2) · Fibrosis (2) · HIV Seropositivity (2) · Hematologic Neoplasms (2) · Hepatitis B (2) · Lymphoma, Follicular (2)
Blood-Borne Infections (119) · Communicable Diseases (119) · Genital Diseases (119) · Urogenital Diseases (119) · Immune System Diseases (118) · Immunologic Deficiency Syndromes (118) · Lentivirus Infections (118) · RNA Virus Infections (118) · Retroviridae Infections (118) · Sexually Transmitted Diseases, Viral (118) · Virus Diseases (118) · Sexually Transmitted Diseases (117) · Infections (115) · Pathological Conditions, Signs and Symptoms (16) · Pathologic Processes (15)
Tenofovir (7) · Emtricitabine (6) · Interleukin-2 (6) · Raltegravir Potassium (6) · Ritonavir (6) · Ribavirin (5) · Lopinavir (4) · dolutegravir (4) · etravirine (4) · peginterferon alfa-2a (4) · Antiretroviral Therapy, Highly Active (3) · Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (3) · Isoniazid (3) · Maraviroc (3) · efavirenz (3)
National Institute of Allergy and Infectious Diseases (NIAID) (16) · ANRS, Emerging Infectious Diseases (6) · National Cancer Institute (NCI) (6) · AIDS Malignancy Consortium (4) · French National Agency for Research on AIDS and Viral Hepatitis (4) · Tibotec Pharmaceuticals, Ireland (4) · ViiV Healthcare (4) · PENTA Foundation (3) · University of North Carolina, Chapel Hill (3) · AIM ImmunoTech Inc. (2) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (2) · Boston Medical Center (2) · Centers for Disease Control and Prevention (2) · Emory University (2) · Fred Hutchinson Cancer Center (2)
United States (63) · France (16) · Spain (15) · Germany (9) · South Africa (9) · Brazil (7) · Canada (6) · Portugal (6) · United Kingdom (6) · Zimbabwe (6) · Botswana (5) · Italy (5) · Puerto Rico (5) · Thailand (5) · Uganda (5)
David R Strayer, MD (2) · Jason V Baker, MD, MS (2) · Mathias Lichterfeld, MD, PhD (2) · Sybil Hosek, PhD (2) · Alberto JS Duarte, Professor (1) · Alessandra Bandera (1) · Anatoli Kamali, MD (1) · Andrew H Miller, MD (1) · Ann Woolfrey (1) · Annemarie Wensing (1) · Anthony Podany, PharmD (1) · Antonio Rivero, MD, PhD (1)
PMID 31179503, PMID 16044019, PMID 17314338, PMID 17434849, PMID 17621237, PMID 17919105, PMID 18230259, PMID 18580611, PMID 18593294, PMID 18596069, PMID 18795960, PMID 18987623, PMID 19104016, PMID 19114852, PMID 19307941, PMID 20607114, PMID 21150563, PMID 21732834, PMID 21881478, PMID 21897852, PMID 21951596, PMID 22210755, PMID 22258265, PMID 22261571, PMID 22525109, PMID 22761759, PMID 22820809, PMID 23299011, PMID 23506243, PMID 23516440, PMID 23667266, PMID 24086333, PMID 24476350, PMID 25108027, PMID 25139963, PMID 25296098, PMID 25398137, PMID 25545673, PMID 26259542, PMID 26423811, PMID 26424549, PMID 26640956, PMID 26696749, PMID 26872154, PMID 27193748, PMID 27439433, PMID 27572401, PMID 27662551, PMID 27811319, PMID 28405623
UM1CA121947 (4), 2014 (3), U01CA121947 (3), 2009 (2), 2008 (1), P01CA018029 (1), P30CA015704 (1), R01DA035054 (1), R01MH090899 (1), R34HL142322 (1), U01AA020780 (1), U01AI068632 (1), U01AI068636 (1), U01AI105872 (1), U01AI110410 (1)