4 recruiting, 3 completed. 7 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Recruiting 4, Completed 3 |
| Phase 1 | 2 | Recruiting 2 |
Follow High Grade Gliomas: new trials by email Literature Review of High Grade Gliomas trials Research Report on High Grade Gliomas
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2 Trial of G207 + 5 Gy Radiation for Children With High-Grade Gliomas G207 - High Grade Gliomas | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 38 | 2026-10-12 | 2026-10-13 |
| Pre-Radiation Chemotherapy for Newly Diagnosed High-Grade Glioma. Pre-radiation temozolomide. - High Grade Gliomas, Glioblastoma | Phase 2 | Recruiting | The Cooper Health System | 70 | 2026-07-13 | 2026-10-09 |
| Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma TGX-007, Valaciclovir - Glioblastoma (GBM), High Grade Gliomas | Phase 1 / Phase 2 | Recruiting | Trogenix ltd | 68 | 2026-04-21 | 2026-10-23 |
| Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). Olaparib; 177Lu-DOTATATE - Solid Tumor Cancer, Medulloblastoma | Phase 1 / Phase 2 | Recruiting | Fundación de investigación HM | 25 | 2024-09-20 | 2026-06-04 |
| Reproducibility of 18F Uptake by Solid Tumors Using PET Imaging Following Intravenous Administration of (18F) Injection Fluciclatide Injection - Solid Tumors, High Grade Gliomas | Phase 2 | Completed | GE Healthcare | 70 | 2009-06-01 | 2014-06-09 |
| Short Course of Radiation for Gliomas in Elderly Patients CyberKnife - High Grade Gliomas | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 26 | 2006-04-01 | 2017-01-27 |
| Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors adjuvant therapy, Temozolomide, Valproic Acid - High Grade Gliomas, Brain Tumors | Phase 2 | Completed | National Cancer Institute (NCI) | 43 | 2006-03-01 | 2016-08-18 |
Glioblastoma (4) · Brain Neoplasms (2) · Glioma (2) · Adrenal Cortex Neoplasms (1) · Adrenal Gland Neoplasms (1) · Astrocytoma (1) · Breast Neoplasms (1) · Carcinoma, Renal Cell (1) · Ependymoma (1) · Esthesioneuroblastoma, Olfactory (1) · Head and Neck Neoplasms (1) · Lung Neoplasms (1) · Medulloblastoma (1) · Meningioma (1) · Neuroblastoma (1)
Neoplasms (5) · Neoplasms by Histologic Type (5) · Neoplasms, Glandular and Epithelial (5) · Neoplasms by Site (4) · Neoplasms, Germ Cell and Embryonal (4) · Neoplasms, Nerve Tissue (4) · Neoplasms, Neuroepithelial (4) · Neuroectodermal Tumors (4) · Astrocytoma (3) · Central Nervous System Neoplasms (3) · Nervous System Diseases (3) · Nervous System Neoplasms (3) · Brain Diseases (2) · Central Nervous System Diseases (2) · Glioma (2)
AH 111585 (1) · Chemotherapy, Adjuvant (1) · Injections (1) · Radiosurgery (1) · Radiotherapy (1) · Temozolomide (1) · Valacyclovir (1) · Valproic Acid (1) · lutetium Lu 177 dotatate (1) · olaparib (1)
Beth Israel Deaconess Medical Center (1) · Fundación de investigación HM (1) · GE Healthcare (1) · M.D. Anderson Cancer Center (1) · National Cancer Institute (NCI) (1) · The Cooper Health System (1) · Trogenix ltd (1)
United States (6) · Spain (1) · United Kingdom (1)
Anand Mahadevan, MD (1) · Gregory Friedman, MD (1) · Jeffrey Winick, Ph.D. (1) · Kevin A Camphausen, M.D. (1) · Marta Osuna Marco, PhD (1)