10 unknown, 9 completed, 2 not yet recruiting, 2 terminated. 27 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 27 | Unknown 10, Completed 9, Not yet recruiting 2, Terminated 2, Withdrawn 2, Active not recruiting 1, Recruiting 1 |
Follow Hepatocellular Carcinoma: new trials by email Literature Review of Hepatocellular Carcinoma trials Research Report on Hepatocellular Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or Hepatocellular Cancer GLP1-RA (semaglutide) - Pancreatic Cancer, Colorectal Cancer | Early Phase 1 | Recruiting | University of Arizona | 30 | 2026-10-10 | 2026-09-18 |
| Efficacy and Safety of Pegylated Interferon Alpha-2β in Patients With Hepatitis B-related Hepatocellular Carcinoma After Radical Resection Peginterferon alfa-2b, TDF, TAF - Hepatocellular Carcinoma, HEPATITIS B CHRONIC | Early Phase 1 | Not yet recruiting | Ningbo No.2 Hospital | 156 | 2026-03-31 | 2026-04-28 |
| Study on the Safety and Efficacy of BST06 Injection in the Treatment of Advanced Hepatocellular Carcinoma Group A, Group B - Hepatocellular Carcinoma | Early Phase 1 | Not yet recruiting | BioSyngen Pte Ltd | 16 | 2024-11-30 | 2024-10-16 |
| Allogeneic Gamma-delta T Cells Combined With Targeted Therapy and Immunotherapy in a Phase 1 Clinical Trial of Hepatocellular Carcinoma Resistant to PD-1 Monoclonal Antibody γδ T cells, PD-1 monoclonal antibody, targeted drugs - Hepatocellular Carcinoma | Early Phase 1 | Unknown | Beijing 302 Hospital | 18 | 2024-04-26 | 2024-04-15 |
| BOLD MRI and FMISO PET for the Assessment of Hypoxic Tumor Microenvironment in Patients with Oligometastatic Liver Cancer Undergoing Yttirum-90 Selective Internal Radiation Therapy 18F-Fluoromisonidazole, Biopsy, Dynamic Contrast-Enhanced Magnetic Resonance Imaging - BCLC Stage a Hepatocellular Carcinoma, BCLC Stage B Hepatocellular Carcinoma | Early Phase 1 | Completed | Emory University | 9 | 2022-04-28 | 2025-03-13 |
| Comparison of Hepatic Intraarterial Versus Systemic Intravenous 68Ga-PSMA PET/CT for Detection of Hepatocellular Carcinoma Gallium Ga 68 Gozetotide, Hepatic Artery Embolization, Positron Emission Tomography and Computed Tomography Scan - Hepatocellular Carcinoma | Early Phase 1 | Withdrawn | Mayo Clinic | 2022-02-11 | 2023-11-07 | |
| Role of DEB-TACE Versus c-TACE in Treatment of HCC Doxorubicin-Eluting Beads - Hepatocellular Carcinoma | Early Phase 1 | Unknown | Sohag University | 30 | 2022-01-01 | 2023-04-12 |
| Safety and Efficacy of Autoimmune Cell Therapy for Patients With Hepatocellular Carcinoma IPM001 - Hepatocellular Carcinoma | Early Phase 1 | Unknown | Huashan Hospital | 23 | 2021-12-31 | 2021-11-03 |
| SBRT + Atezolizumab + Bevacizumab in Resectable HCC Atezolizumab, Bevacizumab, Stereotactic Beam Radiation Therapy (SBRT) - Hepatocellular Carcinoma, Resectable Hepatocellular Carcinoma | Early Phase 1 | Active not recruiting | Massachusetts General Hospital | 20 | 2021-06-18 | 2026-10-20 |
| PD-1 Antibody and Lenvatinib Plus TACE on Downstaging BCLC B/C HCC PD-1 and Lenvatinib Plus TACE - Hepatocellular Carcinoma | Early Phase 1 | Unknown | Fudan University | 50 | 2021-01-01 | 2022-08-18 |
| Fu Zheng Jie Du Hua Yu Principle For Treatment Of Severe HBV Related Hepatocellular Carcinoma (FZJDHYPFTOSHBVHCC) Fu Zheng Jie Du Hua Yu therapy - Hepatocellular Carcinoma | Early Phase 1 | Unknown | Beijing Ditan Hospital | 142 | 2021-01-01 | 2021-12-09 |
| Yang Yin Fu Zheng Jie Du Therapy in HBV Associated Hepatocellular Carcinoma Based on the Platelet Count/Splenic Length-Diameter Ratio Yang Yin Fu Zheng Jie Du therapy, Routine medical care - Hepatocellular Carcinoma | Early Phase 1 | Unknown | Beijing Ditan Hospital | 108 | 2020-10-01 | 2021-12-13 |
| Allogeneic "Gammadelta T Cells (γδ T Cells)" Cell Immunotherapy in Phase 1 Hepatocellular Carcinoma Clinical Trial Ex-vivo expanded allogeneic γδT cells - Hepatocellular Carcinoma | Early Phase 1 | Unknown | Beijing 302 Hospital | 8 | 2020-08-15 | 2020-08-19 |
| Yang Yin Fu Zheng Jie Du Therapy in HBV Related Hepatocellular Carcinoma Induced Anemia (YYFZJDTIHBVRHCIA) Yang Yin Fu Zheng Jie Du therapy, Routine medical care - Hepatocellular Carcinoma | Early Phase 1 | Unknown | Beijing Ditan Hospital | 120 | 2020-07-01 | 2021-11-19 |
| PSMA PET/MRI or PSMA PET/CT for Evaluation of Liver Cancer Biopsy, Computed Tomography, Gallium Ga 68 Gozetotide - Hepatocellular Carcinoma | Early Phase 1 | Completed | Mayo Clinic | 42 | 2020-06-05 | 2024-09-19 |
| Contrast-Enhanced Ultrasound for the Evaluation of Changes in Tumor Blood Flow Surrounding HAE Lumason® - Hepatocellular Carcinoma, Liver Cancer | Early Phase 1 | Terminated | H. Lee Moffitt Cancer Center and Research Institute | 4 | 2020-02-19 | 2023-04-10 |
| 68 Ga PSMA PET/MRI for Hepatocellular Carcinoma 68Ga-PSMA-11 PET/MRI - Hepatocellular Carcinoma | Early Phase 1 | Completed | Ajit H. Goenka, MD | 5 | 2019-06-27 | 2022-07-20 |
| ET 140202 -T Cell Combined With TAE or Sorafenib in the Treatment of Liver Cancer Sorafenib combined with ET140202-T cell, TAE combined with ET140202-T cell, ET140202-T cell - Hepatocellular Carcinoma, Liver Cancer | Early Phase 1 | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 27 | 2019-05-30 | 2019-08-08 |
| Jiu-wei-zhen-xiao Granule for Advanced Hepatocellular Carcinoma Jiu-wei-zhen-xiao Granule - Hepatocellular Carcinoma | Early Phase 1 | Completed | Zhong Wang | 10 | 2019-04-07 | 2021-04-09 |
| Nivolumab and Yttrium-90 in Treating Patients With Liver Cancer Undergoing Surgical Resection Nivolumab, Yttrium Y 90 Glass Microspheres - Hepatocellular Carcinoma | Early Phase 1 | Terminated | Northwestern University | 2 | 2019-02-07 | 2024-02-21 |
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Carcinoma, Hepatocellular (27) · Liver Neoplasms (3) · Breast Neoplasms (1) · Breast Neoplasms, Male (1) · Carcinoma, Ovarian Epithelial (1) · Colorectal Neoplasms (1) · Gastrointestinal Neoplasms (1) · Hepatitis B (1) · Hepatitis B, Chronic (1) · Melanoma (1) · Pancreatic Neoplasms (1)
Adenocarcinoma (27) · Carcinoma (27) · Digestive System Diseases (27) · Digestive System Neoplasms (27) · Liver Diseases (27) · Neoplasms (27) · Neoplasms by Histologic Type (27) · Neoplasms by Site (27) · Neoplasms, Glandular and Epithelial (27) · Liver Neoplasms (24) · Endocrine Gland Neoplasms (2) · Endocrine System Diseases (2) · Adnexal Diseases (1) · Blood-Borne Infections (1) · Breast Diseases (1)
Magnetic Resonance Spectroscopy (3) · 68Ga-DKFZ-PSMA-11 (2) · Biopsy (2) · gallium 68 PSMA-11 (2) · Bevacizumab (1) · Indocyanine Green (1) · Nivolumab (1) · Propranolol (1) · Radiotherapy (1) · atezolizumab (1) · fluoromisonidazole (1) · gadolinium ethoxybenzyl DTPA (1) · lenvatinib (1) · peginterferon alfa-2b (1) · pembrolizumab (1)
Beijing Ditan Hospital (5) · Massachusetts General Hospital (3) · Beijing 302 Hospital (2) · First Affiliated Hospital Xi'an Jiaotong University (2) · Mayo Clinic (2) · Ajit H. Goenka, MD (1) · Ashwin Somasundaram (1) · BioSyngen Pte Ltd (1) · Emory University (1) · Fudan University (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Huashan Hospital (1) · Ningbo No.2 Hospital (1) · Northwestern University (1) · Sohag University (1)
China (12) · United States (12) · Egypt (1)
Aaron J Scott, MD (1) · Ahmed E Mohamed, Master (1) · Ajit H Goenka, MD (1) · Ajit H. Goenka, M.D. (1) · Ashwin Somasundaram, MD (1) · Chang Liu, PhD (1) · Jennifer Sweeney, MD (1) · Jennifer Y Wo, MD (1) · Laura Kulik, MD (1) · Lunxiu Qin, M.D (1) · Melissa McGettigan, MD (1) · Mingyong Han, PhD (1) · Mohamed Z Ali, MD (1) · Mukesh Harisinghani, MD (1) · Nima Kokabi, MD, FRCPC (1)
P30CA060553 (1), P30CA138292 (1)