9 completed, 2 terminated, 1 unknown. 12 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 9, Terminated 2, Unknown 1 |
Follow Hemoglobin SC Disease: new trials by email Literature Review of Hemoglobin SC Disease trials Research Report on Hemoglobin SC Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD. HU-Go app - Sickle Cell Disease, Sickle B+ Thalassemia | Not applicable | Completed | Ann & Robert H Lurie Children's Hospital of Chicago | 68 | 2021-03-02 | 2026-07-31 |
| An mHealth Strategy to Improve Medication Adherence in Adolescents With Sickle Cell Disease MED-Go App - Sickle Cell Disease, Sickle Beta Zero Thalassemia | Not applicable | Completed | Ann & Robert H Lurie Children's Hospital of Chicago | 36 | 2020-09-28 | 2026-07-31 |
| Role of Ajwa Derived Polyphenols in Dyslipidaemias Ajwa Date (phoenix dactylifera) - Dyslipidemias, Hyperglycemia | Not applicable | Unknown | Aga Khan University | 60 | 2019-03-20 | 2019-11-12 |
| Adherence to HU and HRQOL in Patients With Sickle Cell Disease: An Intervention Study Using HU-Go App HU-Go app - Sickle Cell Disease, Sickle B+ Thalassemia | Not applicable | Completed | Ann & Robert H Lurie Children's Hospital of Chicago | 33 | 2018-05-15 | 2021-07-29 |
| Home-based Assessment of PRO Measures in SCD Using A Smartphone App Platform: A Feasibility Study PROs assessment using sickle cell disease mobile app (SCD-app) - Sickle Cell Disease, Sickle Cell Hemoglobin C | Not applicable | Completed | Ann & Robert H Lurie Children's Hospital of Chicago | 40 | 2017-04-04 | 2020-12-21 |
| Effect of Walking on Sand With Dietary Intervention in Overweight Type 2 Diabetes Mellitus Patients. Walking on soft-sand, Walking on Levelled Surface - Walking, Difficulty, Diabetes Mellitus, Type 2 | Not applicable | Completed | Majmaah University | 66 | 2017-01-25 | 2020-09-16 |
| Decision Aid for Therapeutic Options In Sickle Cell Disease Decision Aid Tool, Standard Practice - Sickle Cell Disease, Sickle Cell Anemia | Not applicable | Completed | Emory University | 134 | 2015-01-01 | 2018-10-09 |
| Evaluation of a Training Program for Homozygous Sickle Cell Disease Patients Training Program - Sickle Cell Hemoglobin C Disease, Hemoglobin S Disease | Not applicable | Completed | Centre Hospitalier Universitaire de Saint Etienne | 40 | 2014-09-01 | 2021-09-13 |
| Treatment of Sickle Cell Anemia With Stem Cell Transplant Fludarabine, Cytarabine, Cellular Infusions - Sickle Cell Anemia, Sickle Cell-hemoglobin C Disease | Not applicable | Terminated | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 2 | 2009-09-01 | 2025-05-16 |
| Parent Educational Program for Children With Sickle Cell Disease Parent Educational Support - Hemoglobin SC Disease, Anemia, Sickle Cell | Not applicable | Completed | University of Miami | 73 | 2008-08-01 | 2021-08-02 |
| Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease PAINReportIt (Phase 1 + 2), PAINUCope (Phase 1), PAINConsultN (Phase 2) - Anemia, Sickle Cell, Hemoglobin SC Disease | Not applicable | Completed | University of Illinois at Chicago | 279 | 2007-02-01 | 2026-08-04 |
| Bone Marrow Transplantation, Hemoglobinopathies, SCALLOP Busulfan, Campath 1H, Cyclophosphamide and MESNA - Sickle Cell Disease, Hemoglobin SC | Not applicable | Terminated | Tami D. John | 8 | 2005-07-01 | 2020-07-31 |
Anemia, Sickle Cell (10) · Anemia (3) · Diabetes Mellitus, Type 2 (1) · Dyslipidemias (1) · Hemoglobinopathies (1) · Hyperglycemia (1) · Liver Diseases (1) · Mobility Limitation (1)
Anemia, Hemolytic (12) · Anemia, Hemolytic, Congenital (12) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (12) · Genetic Diseases, Inborn (12) · Hematologic Diseases (12) · Hemic and Lymphatic Diseases (12) · Hemoglobinopathies (11) · Anemia (9) · Anemia, Sickle Cell (2) · Glucose Metabolism Disorders (2) · Metabolic Diseases (2) · Nutritional and Metabolic Diseases (2) · Diabetes Mellitus (1) · Digestive System Diseases (1) · Endocrine System Diseases (1)
Cyclophosphamide (2) · Alemtuzumab (1) · Bortezomib (1) · Busulfan (1) · Clinical Trials, Phase I as Topic (1) · Clinical Trials, Phase II as Topic (1) · Cytarabine (1) · Mesna (1) · Plasma Exchange (1) · Plasmapheresis (1) · Rituximab (1) · Whole-Body Irradiation (1) · fludarabine (1) · fludarabine phosphate (1)
Ann & Robert H Lurie Children's Hospital of Chicago (4) · Aga Khan University (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Emory University (1) · Majmaah University (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1) · Tami D. John (1) · University of Illinois at Chicago (1) · University of Miami (1)
United States (9) · France (1) · Pakistan (1) · Saudi Arabia (1)
Sherif M. Badawy, MD, MS (3) · Daniel Armstrong, PhD (1) · Diana J. Wilkie, PhD (1) · Joanne Filicko-O'Hara, MD (1) · Lakshmanan Krishnamurti, MD (1) · Sherif M Badawy, MD, MS (1) · Tami John, MD (1)
PMID 20158132, PMID 30389037, PMID 31742587, PMID 31799940, PMID 32681734
K23HL150232 (2), 1RC2HL101496 (1), R01HL078536 (1), U54HL090569 (1)