3 completed, 1 recruiting, 1 unknown, 1 withdrawn. 6 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 3, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
Follow Heart Septal Defects: new trials by email Literature Review of Heart Septal Defects trials Research Report on Heart Septal Defects
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Beta-blocker Administration for Cardiomyocyte Division N-thymidine, Urine Collection, Echocardiogram - Tetralogy of Fallot, Double Outlet Right Ventricle | Phase 1 | Recruiting | Weill Medical College of Cornell University | 40 | 2022-12-16 | 2026-10-26 |
| Utilization of Confocal Microscopy During Cardiac Surgery Fluorescite, Cellvizio 100 Series System with Confocal Miniprobes - Atrial Septal Defect | Phase 1 | Completed | Aditya Kaza | 6 | 2018-04-02 | 2020-07-07 |
| Mesoblast Stem Cell Therapy for Patients With Single Ventricle and Borderline Left Ventricle MPC; rexlemestrocel-L - Hypoplastic Left Heart Syndrome, Atrioventricular Canal | Phase 1 / Phase 2 | Unknown | Boston Children's Hospital | 19 | 2017-11-27 | 2023-04-21 |
| Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood Flow IV L-carnitine - Heart Septal Defects, Ventricular, Atrioventricular Septal Defect | Phase 1 | Withdrawn | University of California, San Francisco | 2014-12-01 | 2020-05-06 | |
| A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and Pharmacokinetics Dexmedetomidine - Transposition of the Great Arteries, Tetralogy of Fallot | Phase 1 | Completed | Carelon Research | 119 | 2014-04-02 | 2018-03-23 |
| Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised Protocol Intravenous L-Citrulline, Placebo of Intravenous L-Citrulline - Atrial Septal Defect, Ventricular Septal Defect | Phase 1 / Phase 2 | Completed | Asklepion Pharmaceuticals, LLC | 22 | 2010-09-01 | 2022-07-27 |
Heart Septal Defects, Ventricular (3) · Atrioventricular Septal Defect (2) · Heart Septal Defects, Atrial (2) · Tetralogy of Fallot (2) · Double Outlet Right Ventricle (1) · Endocardial Cushion Defects (1) · Heart Defects, Congenital (1) · Hypoplastic Left Heart Syndrome (1) · Transposition of Great Vessels (1)
Cardiovascular Abnormalities (6) · Cardiovascular Diseases (6) · Congenital Abnormalities (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Heart Diseases (6) · Heart Defects, Congenital (5) · Heart Septal Defects, Ventricular (1) · Transposition of Great Vessels (1)
Carnitine (1) · Dexmedetomidine (1) · Fluorescein (1) · Propranolol (1) · Restraint, Physical (1) · Specimen Handling (1) · Thymidine (1) · Urine Specimen Collection (1)
Aditya Kaza (1) · Asklepion Pharmaceuticals, LLC (1) · Boston Children's Hospital (1) · Carelon Research (1) · University of California, San Francisco (1) · Weill Medical College of Cornell University (1)
United States (6)
Aditya K Kaza (1) · Allan Doctor, MD (1) · Bernhard Kuhn, MD (1) · Catherine Krawczeski, MD (1) · Frederick E Barr, MD (1) · Jeffrey Fineman, MD (1) · Sitaram M Emani, MD (1)
PMID 31623840, PMID 32083653, PMID 34265312
R01HL155597 (1), R56HL128813 (1)