5 completed, 1 recruiting, 1 terminated, 1 unknown. 3 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow Endocardial Cushion Defects: new trials by email Literature Review of Endocardial Cushion Defects trials Research Report on Endocardial Cushion Defects
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NIRS in Congenital Heart Defects - Correlation With Echocardiography NIRS evaluation - Congenital Heart Defect, Single-ventricle | Recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 100 | 2019-10-11 | 2025-06-17 | |
| Mesoblast Stem Cell Therapy for Patients With Single Ventricle and Borderline Left Ventricle MPC; rexlemestrocel-L - Hypoplastic Left Heart Syndrome, Atrioventricular Canal | Phase 1 / Phase 2 | Unknown | Boston Children's Hospital | 19 | 2017-11-27 | 2023-04-21 |
| Measures to Lower the Stress Response in Pediatric Cardiac Surgery Fentanyl (High Dose), Fentanyl (Low Dose), Fentanyl (Low Dose) + Dexmedetomidine - Tetralogy of Fallot (TOF), Ventricular Septal Defects (VSD) | Phase 2 | Completed | Nationwide Children's Hospital | 52 | 2008-11-01 | 2018-07-27 |
| Optimal Timing for Repair of Left to Right Shunt Lesions Ventricular Septal Defects, Persistent Common Atrioventricular Canal | Terminated | Children's Healthcare of Atlanta | 200 | 2005-05-01 | 2012-03-16 | |
| Hypertonic Saline Dextran in Pediatric Cardiac Surgery 7.5% NaCl in 6% dextran 70 solution - Heart Defects, Congenital, Transposition of Great Vessels | Phase 2 | Completed | Oslo University Hospital | 14 | 2003-06-01 | 2011-07-01 |
| Study of Triostat in Infants During Heart Surgery Liothyronine sodium/triiodothyronine, Cardiopulmonary bypass and cardiac surgery - Heart Defects, Congenital | Phase 3 | Completed | Michael Portman | 195 | 2001-04-01 | 2013-08-05 |
| Molecular Genetic Epidemiology of Three Cardiac Defects -SCOR in Pediatric Cardiovascular Disease Cardiovascular Diseases, Heart Diseases | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 1999-01-01 | 2016-05-13 | ||
| Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease Cardiovascular Diseases, Heart Diseases | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 1990-01-01 | 2016-09-28 |
Heart Defects, Congenital (5) · Heart Septal Defects, Ventricular (5) · Hypoplastic Left Heart Syndrome (3) · Cardiovascular Diseases (2) · Heart Diseases (2) · Heart Septal Defects, Atrial (2) · Tetralogy of Fallot (2) · Transposition of Great Vessels (2) · Aortic Coarctation (1) · Atrioventricular Septal Defect (1) · Fractures, Stress (1) · Pulmonary Atresia (1) · Tricuspid Atresia (1) · Univentricular Heart (1)
Cardiovascular Abnormalities (8) · Congenital Abnormalities (8) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (8) · Heart Septal Defects (8) · Cardiovascular Diseases (6) · Heart Diseases (6) · Heart Defects, Congenital (3) · Fractures, Bone (1) · Heart Valve Diseases (1) · Vascular Malformations (1) · Wounds and Injuries (1)
Cardiac Surgical Procedures (1) · Cardiopulmonary Bypass (1) · Dexmedetomidine (1) · Fentanyl (1) · Triiodothyronine (1)
National Heart, Lung, and Blood Institute (NHLBI) (2) · Boston Children's Hospital (1) · Children's Healthcare of Atlanta (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Michael Portman (1) · Nationwide Children's Hospital (1) · Oslo University Hospital (1)
United States (4) · Canada (1)
Ronald Lauer (2) · Aymen N Naguib, MD (1) · Brian Kogon, MD (1) · Gabriel Altit (1) · Gunnar Bentsen, MD (1) · Michael Portman, MD (1) · Sitaram M Emani, MD (1)
P50HL042266 (1), P50HL062178 (1)